Mdpv

[snapper]

What lasting consequences to cognitive function and emotional stability are you referring to, nanobrain ? Does it make you manic ? For how long (ie - a la post MDMA crankiness ?)

Snapper

[thadj]

Nostawk, PM me your email addy, i'll send you the article.

thadj

[nanobrain]

^^since it fairly obviates the need for sleep or nutrition, loss of associative memory (storage and recall) has been reported by some after a 'run', together with auditory hallucinations of a particularly catlike-mewling nature.

while others complain of comedowns lasting months from one-time admin, yet covet the microgram crumbs others claim not to note any effects, but they are deluded as motorics are exaggerated. both groups appear to covet the remaining micrograms. no dirty carpet surface was safe from the fienders fine eyetoothcombs.

i aslo feel it has an effect on some cerebellum / spatial coordination / balance-related structures as there is noted peripheral jerkiness to movements and a lesser perceived but still noted decrease in hand-eye coordination, which, if left unmitigated, with prolonged use becomes rather severe.

this raises flags of caution in re destruction of dopaminergic neurons (early Parkinsonism) probably in the substantia nigra - how lasting these consequences remains to be seen.

the potency of these compounds is high and the targeting of the molecules so specific that unless the keys are perfectly reflective of particular neuronal subsets topology, even trace impurities could prove active and neurologically damaging.

as for permanent reorientation of the reward circuitry value systems, it appearsto be self-evident among a group of subjects.

i am sure the emergency room cases will start showing up.
exercise caution with your animals.

Reputation Comments on this post:

Thanks for all your wisdom in this thread.

[fatal]

so what im hearing is that there is basically nothing good about this except the rush... ok so then lets start a forum pool... the over under for scheduling is set at 9 months. any takers?

[rodent]

SWIM hasn't any experience with it but if he were to guess it would be far more than nine months to scheduling. BZP (not making any comparisons here) made it's rounds as a stimulant for some years before it's scheduling.

The long/difficult 'come-downs' SWIM's read in this here thread don't make it sound too appealing...

[Nagognog2]

Nano, sounds like a description for the China White of the entactogenic-stimulant family. If you recall what that designer-drug of the fentanyl-family was found to do. Thanks for sounding the warning bell. Do keep us informed on this.

[snapper]

BZP is a relatively safe compound and has a track record, having been available around 8+ years and with documented human trials.
MDPV is seeming to not be safe at all, or at least suspect. There are no studies documenting side effects to speak of and only anecdotal trials. Many of the reports make this stuff sound like crack with a worse hangover. So far not very confidence inspiring. Maybe if SWIU are lucky it will go away. As SWIM understands it it is hard to make? Perhaps those distributing this should take a hint and give it up.

Snapper

[nanobrain]

well, the adage that if the only tool you have is a hammer, every job becomes a nail seems to apply.

yet as Confuse-u-is (as different from that other guy) said, one must know his true name, and the name of the pentan is not hammer - so perhaps its job is not that of a nail pounder...

[radio879]

i aslo feel it has an effect on some cerebellum / spatial coordination / balance-related structures as there is noted peripheral jerkiness to movements and a lesser perceived but still noted decrease in hand-eye coordination, which, if left unmitigated, with prolonged use becomes rather severe.

This is odd - I find it actually inproves hand/eye coordination very very much so.. my hands are VERY steady, and -- well, as nanobrain would know, its the same kind of steadyness, accuracy, fluidity of motion that a low dose of DMT gives, took a little earlier and my hands are visibilly not shaking at all (well ok, if i look hard enough its there just WAY less than sober if you know what i mean).

Moving around and doing things my coordination is greatly improved - all similar to low dose DMT - but unlike DMT, the brain is "cranked up"/overclocked to do these things.. where with DMT, (i'd expect only nanobrain to understand what i'm talking about with DMT ahem / experienced) the brain makes up for the increase in coordination/fluidity (higher "framerate" vision) by reducing energy load on other parts of the brain like certain visual details (a little more basic geometry, more is discarded in favour of increased coord/fluidity/etc).

So nanobrain, you have mixed DMT and MDPV.. how is this? very curious.. Does DMT kill some of the side effects you experience with MDPV?

Reputation Comments on this post:

self incrimination

[daeron]

what gives with that complete off topic post about DMT?

hey, forgive me if im wrong, but arent you that RC vendor wannabe guy who was spamming everywun about DOC and than passed some DOI as 2ci? Hey didnt you get like raided or something, hows that thing going? Did LE made you snitch? How come youre free?

Reputation Comments on this post:

Go Dr. D!!!

[radiometer]

^ Positive rep left for the informative post, but please peruse the rules regarding self-incrimination.

[nanobrain]

renal issues may become noted, the cases are coming in. dont forget to hydrate your rats as they may forget.

do not violate rules and do not abandon caution.

stop using now if you can.

Reputation Comments on this post:

good reminder on the hydration. bears repeating. more info on the cases mentioned would be even better!

[snapper]

Nanobrain,

Specifically what renal issues. Actually diagnosed renal issues, or subjective ones ? Does MDPV just stress kidneys by decreasing bloodflow to them, or does it do more permanent damage after the fact ?

A brief subjective report finds MDPV to be a clean, short acting stimulant in league with BZP minus the body load. No strong euphoric component, and a strong drive to re-dose when vaporized. SWIM has so far tried vaporizations from 1 - 2 mg. Combines well with kratom, each being additive to the other.

Given that it seems to have no empathogenic or psychedelic effects, SWIM feels it is limited in value unless one is a tweaker. No side effects of note at this level of dosage except sleep loss.

Snapper

[fastandbulbous]

Basically, at low doses it's ideal for getting work done without the effects of fatigue denegrating perfotmance - be warned though, the 'more is better' approach with this drug is a sure-fire route to disaster. I've found that 2-3mg rectally or IM (yes aseptic technique followed closely) is good. Exceed 5mg and your performance will suffer badly.

It's not a drug for your average speedfreak, as they seem unable to moderate intake. Basically if you find the occasional dose of methylphenidate to be of use, this will substitute admirably otherwise forget it

Reputation Comments on this post:

Good post

[nanobrain]

^precisely put

[snapper]

Well, for what it's worth, SWIM has heard oral and non-oral routes seem to have about an equal overall effect, though naturally the latter comes on much faster and is shorter acting; feels similar to ritalin, and provides little or no euphoria. Smoked doses give a rush, but not a euphoric rush, just a strong stimulant effect. MDPV has the portential, like most stimulants, to become habit forming. Though there is no empathogenic rush, it is tempting to redose on comedown (ie - methylone). SWIM has heard only 1-3 mg doses have been used for assay so far due to this molecule's rep., but the dose will be stepped up a bit a few more times before posting a report.
Note that SWIM has heard MDPV mixes with cannabis (which seems to negate a lot of MDPVs effects) and alcohol with no added side effects, and actually compliments a 6mg dose of 5meomipt quite well on the MDPV comedown. Kratom combines well in low doses (2-4 mg), but can trigger anxiety and tachycardia at higher ones, so high doses may be unpleasant.
Seems like MDPV would be a good combination with something else to minimize its negative effects and round out its effects.
This report is a bit redundant, but given the scarcity of this compound, any info is useful.
SWIM has heard that the duration of MDPV is less than was reported. SWIM heard it only lasts about 6 hours, with a good 2 hours of peak effect. Maybe at higher doses duration will increase?

[Frogster]

Originally Posted by snapper

SWIM has heard that the duration of MDPV is less than was reported. SWIM heard it only lasts about 6 hours, with a good 2 hours of peak effect. Maybe at higher doses duration will increase?

Please remember that the Dosage/Effect response of MDPV is not smooth but very drastic. Even slightly higher Doses can lead to the often mentioned bad side effects. Be very careful when SWIY increases the dose, especially when SWIY redoses.

[nanobrain]

depending on the condition and family tradition of your rats metabolic predisposition and neurotransmitter level depletion, duration varies from zero time units to 12++ hours post-admin.

[allyourbase]

no, there should be no given methods to test for this.

SWIM's experiences with this drug are as follows: 5mg insufflated is about the equivelent to a half gram of cocaine, in feeling and duration, no numbness but the same or extremely similar core CNS stimulation and mental excitation occur. SWIM finds this in no way similar, or even comperable to any amphetamine SWIM has yet tried.

SWIM has tried this compound approximately 5 times now and has never felt its effect longer than an hour and a half. SWIM's body must be cheating him.

[fastandbulbous]

Originally Posted by allyourbase

SWIM's experiences with this drug are as follows: 5mg insufflated is about the equivelent to a half gram of cocaine, in feeling and duration, no numbness but the same or extremely similar core CNS stimulation and mental excitation occur. SWIM finds this in no way similar, or even comperable to any amphetamine SWIM has yet tried.

Although it has the same mechanism of action as cocaine, I find that MDPV has only slight comparisons with cocaine. As well as turning me into a total arrogant, egotistical cunt, I've found that cocaine produces a very fuzzy, stoned type of intoxication where clear thinking is difficult; in contrast, lower doses of MDPV produces a clarity of thought far superior to just about every other stimulant I've ever tried. The only ones that have come close are fencamfamine & prolintane (although prolintane has only mild CNS locomotor stimulation in comparison with MDPV & fencamfamine) - from what I've read about it, the only one I'd expect to surpass MDPV for clarity is 4-methylaminorex

Reputation Comments on this post:

Good post

[turkeyphant]

Thank you for the valuable information, fb. In the future please try to avoid self-incrimination. Kindly edit your post.

[BIG-TRON]

For info try searchin MDPK is the same compound different name, swim just ordered it along with MET freebase & 2Ce

[fastandbulbous]

It mixes extremely well with LSD in small doses and does seem to boost the effect of the LSD. 4mg taken rectally with one good blotter caused time dilation of the order that I've very rarely had and made the blotter feel like twice the dose for about 4 hours.

Again, as long as you don't go at it like your average speedfreak (and effectively poison your body), this is a very useful, extremely efficient, clear headed stimulant. I just hope it stays below the legal radar, but all it takes is one fuckwit... and we all know how that scenario goes

Reputation Comments on this post:

Excellent synopsis.

[Nicaine]

SWIM is dying to try MDPV (being a major fan of dopamine reuptake inhibition). Sounds like it might be worth taking small doses along with other subbies as well, to add/enhance dopaminergic components of the high. In fact this latter use sounds like a better idea than trying to get high on MDPV alone, particularly if it really causes panic attacks that easily.

He thinks he'll order some & report back later. Thanks for the reports everyone, looks like this one could be worthwhile (but only if extreme caution is used).

P.S. SWIM doesn't quite get the claims there's no euphoria though. If this chem affects dopamine, there has to be some euphoria. Also, SWIM is wondering if anyone's tested its potential to improve sexual encounters/experiences.

Edit -- never mind on the sexual thing, SWIM saw that someone commented on a small injected dosage. SWIM can't wait to receive some of this stuff, his lab monkey's gonna go bananas!

[fastandbulbous]

I don't understand the 'no euphoria' either as it makes interesting tasks completely fascinating. It's also one of the best sexual stimulants you could wish for (again - not going over a certain limit is essential).

Maybe I've just got a slightly offset neurochemistry!