Ho-MiPT free base

[rxbandit]

SWIM was wondering how one would go about converting a freebase of HO-MiPT to a stable salt or if the basic freebase is active since it is non water soluble. SWIM also wonders the most prefered method of dosing using miprocin and if smoking, insufflation or plugging are more effective then oral dosing.

[illuminati boy]

Gonna take a guess and figure SWIRx is wondering about 4-HO-MiPT… at any rate sounds like SWIRx is asking whether the freebase is maybe orally active and if not how to make a nice little salt out of the bugger eh?

Well while not the most chemically astute chap in these parts, I would guess all that would be needed would be an acid (acetic, ascorbic, etc.) or just some HCl. I would guess the freebase compound to be active based on this quote from TiHKAL:

“In all of these studies, the acetate is the ester, and some of these are free bases, some are the hydrochloride salts and some are the fumarate salts.”

I would also guess the simplest way to put the freebase into a solution with H2O would be as suggested by this line from TiHKAL:

“I suspended the solids in water, and a drop of HCl put it into solution immediately.”

Hopefully a little help.

I B

[nostawk]

I hear 4-ho-mipt is not the most stable compound, so dissolving in liquid could be a bad idea

[radiometer]

It seems to me that the only reason to salt the material would be greater stability, yes?

A little bird told me this, I've never done it myself:

Be sure to use distilled water. Put the freebase in the water; it will not dissolve (if it dissolves, you already have a salt). Add a single drop of HCl (muriatic acid) and stir. Wait a few minutes - if stirring doesn't dissolve the material, add another drop. Mix and wait again. The material should dissolve within a few drops - be patient, stir and wait.

To obtain dry crystals, simply evaporate the solution.

[rxbandit]

would this little birdie know if its possible to use a nonpolar solvent since evaping is easier or if freezing the solution would precipitate out the chems.

[grandbaby]

From another source:

"In order to convert a freebase into an HCl salt, place chemical in distilled water and add dilute hydrochloric acid drop-wise, while stirring and waiting (may take up to a few minutes depending on graininess and other parameters) after each drop. After a few drops, the solid will have dissolved completely; you now have an HCl salt with a little bit of excess hydrochlorid acid.

If you would like to receive dry crystals, let the water and excess HCl evaporate. A few drops of pure ethanol or methanol can speed this up when material is almost dry."

[BlueMystic]

rxbandit~ Let us know what route you take and its results.

[Nagognog2]

Grandbaby: Many organic molecules do not like to be turned into an .HCl and evaporated out of the solution. They will revert and the acid will eat the desired molecule.

Personally I would suggest that the monkey attempt to return it and tell the supplier to handle this problem. Otherwise freeze it in as airless state as possible. If desired to put a bit in solution: Use lemon juice to form a .citrate.

[nostawk]

Mg scales can be found for less than 100$.



from reading a few threads here about said compound, I would be worried about its stability in alcohols and water.


Also it not being offered as a salt makes me wonder why?...



The freebase is active mmmmhmmmmmmmmmhhhhhhhhhhhhhhhhhmmmmmm

[rxbandit]

yes i figured that out from doing some research, althought SWIM is worried about it degrading over time. SWIM thinks getting some vitamin C(ascorbic acid) caps from his local health food store putting a 20 mg dose in with an excess of vitamin C and a few drops of water might help its stability and provide the stomach acidity desired for tryptamine absorption. but appreciates everyones impute greatly and would appreciate more on this approach

[snapper]

Freebase is very active orally. Though the onset is the same as oral, one can also vaporize it (maybe to bypass a full stomach ?). It cannot be insufflated in freebase form. If one is worried about stability, one should worry regardless of whether it is a salt or not. Keep it frozen, dark and dry and it will last a reasonable amount of time. Those who have a freebase have more active product by weight, anyways.
If SWIM were to convert to salt, SWIM would consider a weak acid to avoid Nagognog2's pitfall. Reaction time would be longer however, and given that this particular product polymerizes and/or degrades in solution, this could also present a problem.
Might just want to leave it alone.

Snapper

[rxbandit]

i think im just going to leave it as be as it is working out fine although i do worry about the stability in the warm summer sun when transporting it to SWIMs trip destination. 26 mgs wrecked SWIM and blew LSD away. rainbow skys, morphing starry streets, amazon rainforests forever growing foliage, exotic cars, elven houses, it was ridiculous although i want to figure out...

[snapper]

Try a gelcap.

Snapper