Meth and SSRI ?

[t3rror]

What are the effects of taking meth while on ssri antidepresents??
any SWIY have expeience in this?

[Ahuaeynjx]

SWIM would suggest against such a combination since it will most likely upset your dopamine/serotonin balance and turn SWIY into a wimp, sexually (and ethically about it) speaking. SWIY have to understand that you can well combine alot of drugs that play around with brain hormones (NEVER THROW A MAO-I IN THERE) but that it's a definite no-no with any form of sexuality even mentally induced.

Just SWIM's 3 cents... Be safe.

Namase,

Ahu

[~lostgurl~]

SWIM has been taking Effexor (SSNRI) for 18 months and has been taking meth most days too. SWIM hasn't noticed any obvious side affects - not to say there are none - but has found the come down from meth alot easier. The overwhelming craving for more has been significantly reduced, craving is still there but if SWIM can't afford it then SWIM goes without and it is no biggie.

[Ahuaeynjx]

Well of course it's a form of legal Extasy (SSRI), no surprise it makes SWIY feel better for a while. But thats a combo that will both drain SWIY's bioelectric capacity by draining SWIY's dopamine then keeping serotonin away from the synapses. Bee careful when playing with synthetic hormone enhancers, SWIY knowing not his body will end up as dry as a bonzai, hormonally !

Namase,

Ahu

P.S. - I always say to avoid those evil molecules ! Get natural !

Reputation Comments on this post:

SSRI's are NOT ecstacy: Legal or otherwise. Misleading (and incomprehensible) post

[Ahuaeynjx]

I even got bad comments for saying Extasy was a SSRI ! Well of course technically it isn't ; but at high dose it certainly have an SSRI (and more) effect... It makes me laugh to see people play on words to feel better about themselves.

Sceletium tortuosum at the right dosage with some st-John's wort and some herbal stimulant is definately what SWIM would be going for instead !

Namase,

Ahu

Reputation Comments on this post:

Unjustified, does not even make sense

[mick mouse]

SWIM has been taking 60 mg. of Cymbalta (duloxetine HCL), which is a re-uptake inhibitor of both serotonin and dopamine. SWIM agrees with Laura76, it seems to prolong the effects of meth somewhat, but the bodyload is far easier as it spins down and the craving is much less intense. While duloxetine is normally prescribed as a high-medium to major anti-depressent, SWIMs doctor prescribed it for pain. It actually works well for that, as SWIM's normal pain meds are morphene 30 mg for breakthrough pain as needed and MS Contin 30mg twice daily. With the Cymbalta, SWIM can hypotheticly save up the opiates for a rainy day

[ziphren]

I heard it is Very Dangerous (tm). SWIM, however, loves it, and has had no problems.

[Psych0naut]

SSRI's together with drugs that release serotonine(like MDMA) can cause serotonine syndrome which is very dangerous and can be fatal.
SWIM isn't 100% sure that Methamphetamine releases serotonine as well, but as far as he remembers it does, so combined with a SSRI it can cause serotonine syndrome.

[~lostgurl~]

Amphetamines release stores of norepinephrine from nerve endings, thus promoting nerve impulse transmission. The behavioral effects of amphetamine itself comes from its action on the monoamine transporter DAT (dopamine transporter) which leads to an increase in the amount of dopamine in the synaptic cleft. Other amphetamines may have other modes of action.