What causes this specific
opiate withdrawal symptom? Frequent Urination
A
withdrawal symptom which probably has nothing to do with the brain is the frequent urge to urinate during withdrawal.
During withdrawal I really often have to go to the toilet. In order to find a (herbal?) remedy, I want to understand how this happens.
Maybe it can be explained when I understand the cause of the urinary retention caused by
opioids. But I cannot find anything about this, too. Why do you have to urinate so often in withdrawal?
(Together with the sweating causes this probably a greater loss of fluid and electrolytes. What is the best way to compensate this? Drinking much water? Could cause even more sweating and cannot compensate electrolyte loss. - Drinking green tea? Good because of flavonoids? Bad because of coffeine? - Electrolyte drinks? Homemade recipe?)
As I looked up "Vasopressin" in another case, I found that it is also called "antidiuretic hormone" (ADH). I alwasy thought that it plays a role in inflammation and blood pressure.
But the first sentence in the english version of wikipedia is:
Quote:
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One of the most important roles of AVP is to regulate the body's retention of water; it is released when the body is dehydrated and causes the kidneys to conserve water, thus concentrating the urine and reducing urine volume.
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and later on I found a short remark
Quote:
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In the perioperative period, the effects of surgical stress and some commonly used medications (e.g., opiates, syntocinon, anti-emetics) lead to a similar state of excess vasopressin secretion. This may cause mild hyponatremia for several days.
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So opiates seem to be responsible for an augmented release of the antidiuretic hormone. Can this be the cause of the urinary retension? Why is is mainly a problem when somebody starts to take opioides? After a time of regularly use, it seems that nearly nobody has this problem anymore.
Does the body gets acclimated to the augmented ADH release in some way? I have no theory what happens during withdrawal but it looks like as there could be a connection between ADH secretion and the frequent urinations during withdrawal.
Maybe there are some plants that can also lead to vasopressin secretion (but in a lighter way as opioids)? That could possibly help..?
Who knows something about that?