Hmmm, bupropion (Wellbutrin, Zyban) is
used as a smoking cessation aid, so there is some sort of way one could imagine it to be useful in opiate withdrawal
, but... that's a very long stretch, and I would say it's probably too long. Technically it may help somewhat
, but there is a chance that you may experience side effects
that completely offset any potential benefit.
And that's not even to talk about other (possibly serious) issues that could arise. Bupropion is an inhibitor of a liver cytochrome that plays a role in the metabolization of certain drugs. (A quick Google search yields CYP2D6, but I actually think it's a different one. I'll have to look at that some more.) That means that it slows down the metabolization of other drugs that use the same enzyme, and I think that hydrocodone is one of those drugs. It may affect oxycodone as well. This all means that it would probably not be a good idea to start taking bupropion at this point in time.
More generally, I wonder why you were supposed to take bupropion, but decided not to? If whatever you were diagnosed with is still present, it might be a good idea to check that out and look at whether you may need some help with that. But that is up to you of course...