propoxyphene extraction?

[Forthesevenlakes]

After looking through the search engine, it doesnt seem like a CWE is possible on propxyphene (darvocet), but SWIM is thinking there should be a way to separate it from the acetaminophen. SWIM has heard chloroform suggested, but is wondering if there may be a more simple solvent that could work, or if some kind of A-B extraction would be possible. SWIM is going to look in the merck index later, but wants to see if anyone else has any ready-made methods.

[Ethyl]

Swie has never tried propoxyphene extraction, but he has tryed propoxyphene IV ampoules, he did told me that 75 to 175mg gives quite a rush with lots of needles in your head...

Propoxyphene hydrochloride, USP is an odorless, white crystalline powder with a bitter taste. It is freely soluble in water

It is freely soluble in water there you have it...

[Bajeda]

Take note that if you have Darvocet-N, which is comprised of Propoxyphene napsylate, a more stable form of Propoxyphene hydrochloride, you are out of luck as far as CWE goes as it isn't very water soluble.

[Ethyl]

Originally Posted by Bajeda

Take note that if you have Darvocet-N, which is comprised of Propoxyphene napsylate, a more stable form of Propoxyphene hydrochloride, you are out of luck as far as CWE goes as it isn't very water soluble.

In that case i think converting the propoxyphene to a base and then use one of this solvents to extract the base: petroleum ether, pentane, benzene. Paracetamol would not dissolve in this solvents.

[acolon_5]

SWIM has to question if an extraction is impossible. One link SWIM found say that propoxyphene hcl is freely soluble in water. Another says it is soluble in a week acid but not in water.


http://www.newton.dep.anl.gov/askasc.../chem00954.htm

http://www.patentstorm.us/patents/53...scription.html

Which is it? If it is barely soluble in water, couldn't the APAP be extracted with a hot water extraction leaving only the binders and propoxyphene?

If it IS soluble in water, wouldn't a CWE work?

Also, if it is soluble in a week acid solution, say....citric or acetic acid, couldn't a CWE be used with a little vinegar or citric acid? Would that leave behind the APAP?

SWIM has a friend, who has a pet hedgehog that is getting a few 100 of these soon (HCL, not -N), he will try some experiments and see what works and what doesn't.

[crunchyblack]

If i was SWIM. I wouldn't even waste time with propoxyphene as it's a crappy buzz and pretty toxic from what I have read.

[Ethyl]

Originally Posted by crunchyblack

If i was SWIM. I wouldn't even waste time with propoxyphene as it's a crappy buzz and pretty toxic from what I have read.

75-150mg IV use is quite a rush , for the opiate naive/no tolerance user.

[Ethyl]

Originally Posted by acolon_5

SWIM has to question if an extraction is impossible. One link SWIM found say that propoxyphene hcl is freely soluble in water. Another says it is soluble in a week acid but not in water.


http://www.newton.dep.anl.gov/askasc.../chem00954.htm

http://www.patentstorm.us/patents/53...scription.html

Which is it? If it is barely soluble in water, couldn't the APAP be extracted with a hot water extraction leaving only the binders and propoxyphene?

If it IS soluble in water, wouldn't a CWE work?

Also, if it is soluble in a week acid solution, say....citric or acetic acid, couldn't a CWE be used with a little vinegar or citric acid? Would that leave behind the APAP?

SWIM has a friend, who has a pet hedgehog that is getting a few 100 of these soon (HCL, not -N), he will try some experiments and see what works and what doesn't.

Just let SWIY try for himself and see if it works! If SWIY save the remains for the possibility of not being watersolube and you have nothing to loose.

[acolon_5]

Similar to A/B Extraction...just basify, add non polar, seperate, and evap? This I assume would also work with the HCL salt, yes? At some point SWIM is going to try a few experiments on the 175 capsules he just got. SWIM told me the buzz is pretty crappy.

[Ethyl]

Originally Posted by acolon_5

Similar to A/B Extraction...just basify, add non polar, seperate, and evap? This I assume would also work with the HCL salt, yes? At some point SWIM is going to try a few experiments on the 175 capsules he just got. SWIM told me the buzz is pretty crappy.

It will work with the HCL too, but with the HCL salt you can use a simple CWE as it is freely soluble in water.

Yeah, it's a simple A/B extraction, that would remove all impurities if done right as you might know..

If SWIY does not have any tolerance to stronger opiates and swiy are into IV use, then propoxyphene may deserve SWIY a surprise, swie has allways eard that it has a good rush when IV.

BUT REMEMBER: NEVER IV PILLS!

Originally Posted by acolon_5

Similar to A/B Extraction...just basify, add non polar, seperate, and evap? This I assume would also work with the HCL salt, yes?

If swiy want a pure product, swiy allmost certanly will need to convert the propoxy to a hcl "again" to purify even more, pills may have stuff that is soluble in non polar too.

Reputation Comments on this post:

Thanks! Helpful stuff.