Dose - Benzodiazepine Equivalent Doses

[Jatelka]

Thought this might be useful.

Contributions to it have also come from darkbreed, kareena, Moda00, and WeareStardust

Brand names for these drugs can be found here...
http://www.drugs-forum.com/forum/sho...ht=brand+names

She appreciates that benzos have different sedative, anxiolytic and myorelaxant properties but this is essentially a tool for converting to diazepam (usually for withdrawal purposes)

Benzodiazepine	Half-Life (hours)	Equivalent dose (to 10mg Diazepam)	Indication
Alprazolam	6-12	0.5mg	Anxiety
Bromazepam	10-20	5-6mg	Anxiety
Brotizolam	6-7	0.25mg	Anxiety
Camazepam	6-11	? equivalence	? Indication
Chlordiazepoxide	5-30 (36-200 for active metabolite)	25mg	Anxiety, Alcohol Withdrawal
Cinolazapam	9	40mg	? equivalence
Clobazam	12-60	20mg	Anxiety, Anticonvulsant
Clonazepam	18-50	0.5mg	Anxiety (not in UK), Anticonvulsant
Chlorazepate	36-200 (including active metabolite)	15mg	Anxiety
Clotiazepam	6-7	5-10mg	? indication
Cloxazolam	55-77	1-2mg	? indication
Delorazepam	60-200	? equivalence	? Indication
Diazepam	20-100 (36-200 for active metabolite)	10mg	Anxiety, Anticonvulsant
Doxefazepam	3-4	? equivalence	? Indication
Estazolam	10-24	1-2mg	Hypnotic
Etizolam	3-15	1-2mg	? indication
Fludiazepam	23-48	? equivalence	? Indication
Flunitrazepam	18-36 (36-200 for active metabolite)	1mg	Hypnotic
Flurazepam	40-250 (including active metabolite)	15-30mg	Hypnotic
Halazepam	15-35 (15-100 for active metabolite)	40mg	Anxiety
Haloxazolam	? Half life	5mg	? indication
Ketazolam	30-100 (36-200 including active metabolite)	15-30mg	Anxiety
Loprazolam	6-12	1-2mg	Hypnotic
Lorazepam	10-20	1mg	Anxiety, Anticonvulsant
Lormetazepam	10-12	1-2mg	Hypnotic
Medazepam	36-200	10mg	Anxiety
Mexazolam	70	1mg	? indication
Midazolam	2-6	5mg	Sedation
Nimetazepam	? Half-life	? equivalence	? Indication
Nitrazepam	15-38	10mg	Hypnotic
Nordazepam	36-200	10mg	Anxiety
Oxazepam	4-15	20mg	Anxiety
Oxazolam	10-20 (36-200 for active metabolite)	60mg	? indication
Pinazepam	40-100 (36-200 for active metabolite)	20mg	? indication
Prazepam	36-200 (including active metabolite)	10-20mg	Anxiety
Quazepam	25-100	20mg	Hypnotic
Temazepam	8-22	20mg	Hypnotic
Tofisopam	6-8	100mg	? indication
Triazolam	2	0.5mg	Hypnotic

Non-benzodiazepines with similar effects

Zaleplon (Sonata) 2, 20mg
Zolpidem (Ambien) 2, 20mg
Zopiclone (Zimovane) 5-6, 15mg

Sources: Ashton, pubmed, the lovely folk from df

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