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Tryptamines Tryptamines and indoles.

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  #1  
Old 21-02-2006, 11:27
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Question AMT (alpha-methyltryptamine)

I've been researching this compound and it seems like it could be a goodie, does anyone have any experience with it?

(don't you UTFSE me!)

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Old 21-02-2006, 17:23
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Yes, I know someone who enjoyed it. He said it was like a stimulant with some euphoriant properties. The only problem, if I recall, is that it lasts a really long time for a tryptamine. Something like 10 hours.
Sorry, that's all I've got on it. It was banned in the US with BZP and Foxy.
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Old 21-02-2006, 18:07
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Thanks boss, i found plenty of stuff about it on one of the other forums anyhow. Still sounds pretty yummy to me, smoke the freebase and it'll shorten the duration. 7-8 hours sounds much more manageable.
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Old 22-02-2006, 00:53
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SWIM has been looking real deeply into AMT, experience reports seem kinda inconsistent but then again their are a few not-so smart people posting experiences online. Looks like a goodie, though
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Old 22-02-2006, 01:19
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Yeah, i agree, i'd think for me the sweet spot would be around 30/40mg not the 100/150mg's i've seen in some reports!
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Old 22-02-2006, 03:54
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From what I have read AMT sounds a little on the toxic side, so be carefull with it. It's cousin 5-meo-AMT is definitely toxic.
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Old 22-02-2006, 04:51
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There is a plethora of information on a-MT around here - UTFSE! (nyah! nyah!). Bongo laid his paws on it back around 1980 when it was legal and available from a major chemical company in the USA. He would agree that 40mg is optimal for this one - orally. He never tried to smoke it. The effects orally do last about 24 hours. It is a MAOI, so extreme caution is to be advised if your jellyfish ever runs across it. Bongo made the mistake of having a few sips of beer around the 16 hour mark once. The result was a pounding migraine for the next 8 hours.

All in all, Bongo found it to be rather unpleasant. The body load (without the sips of beer) was quite nasty. Not really worth the psychedelic effects. But it did open up a channel of telepathy between his circle of test-pilots that was quite remarkable: Able to sit in a room with his cohorts and write down each other's thoughts and images. This effect lasted well after the drug effect had worn off and carried over into dreams.

For this particular effect, Bongo and Company found it worthwhile to repeat a few times to study this phenomena further. But once the little brown bottle was empty (still sitting on a shelf washed out clean), there was no desire to re-order same.

As an aside, it took Bongo many years to gather together enough information to be certain that this was the correct compound that Bongo was looking for. The literary references that compelled Bongo to seek out this molecule all mentioned a research chemical that was called IT-290. But nothing stated what the heck IT-290 stood for. Only upon springing for the hardback edition of The Hallucinogens by Hoffer and Osmond ($$$) did Bongo finally conclude that IT-290 (mentioned by Ken Kesey et al from the Menlo Park "White Room" experiments) was, in fact, d,l-alpha-Methyltryptamine. Seemingly a Holy Grail of the early psychedelics.

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Old 22-02-2006, 10:03
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The MAOI effects i have been lead to believe are negligable (-1000x compared to harmine) in this context. I would be cautious anyway though. This compound has a rich history, It used to be known as Indopane in the USSR and was used as an aintidepressant! Lucky ruskies!
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Old 22-02-2006, 17:39
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MAOI's are to be respected. Saying something is a "negligable" MAOI is like saying something is a little bit fatal. Always follow the full set of don'ts when working with any MAOI. Bongo got off easy with an 8 hour migraine while in a highly accentuated state of awareness. NOT suggested. He also knows a chimp who mixed a benzodiazepine with a-Ethyltryptamine to help the monkey get some sleep. That chimp landed in an emergency room in a hypotensive crisis. Read: His blood pressure fell through the floorboards and the chimp passed out cold. a-ET is also reported to be a "mild" MAOI.

Consider your jellyfish warned.
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Old 22-02-2006, 22:31
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I've checked the journals and i have seen no mention about contraindictions between maoi's and benzos, quite the contrary- benzos are often given to complement maoi antidepressants.

i only wish i could read russian so i could find more refs to indopane :\ , i don't see how this could have been said chimps downfall? perhaps this silly monkey just ate too much? highly depressed from mr benzo?

Some mode of action other than related to maoi but still related to the AET was responsible methinks.

I have access to a lot of material at uni, i will have a look in the 'morrow, or day after. (if i remember past the next 5 minutes)
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Old 22-02-2006, 22:41
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150mg a-ET + 30mg flurazepam. Ambulance. Period. Got it? Or do I need to tattoo it on my forehead?
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Old 22-02-2006, 23:52
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That's a rediculous amount of both. SWIM had found that benzos accentuated AMT nicely, killing some of the jitters and that really annoying nystagmus SWIM always got if > 50mg. SWIM also tested MAOI activity with not orally active tryptamines and found them to still be not orally active. I think it is not so much an MAOI effect as the generally less predictable side effects of this compound at higher doses. SWIM eventually learned to appreciate this compound at lower doses FAR more than at high ones, particularly if combined with another tryptamine to kick into overdrive.

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Old 23-02-2006, 00:10
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Swim has had great experiences with a-MT. It was one of the first exotic chemicals swim ever tried and to this day think of it as one of the more powerful and deep psychodelics.

Swim hasn't actually used it for going on 3 years now, due to the bodyload and shere length of trip, but has a lifetimes supples sat aside for when it's time.
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Old 23-02-2006, 00:14
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Thumbs up

tattoo please.
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Old 23-02-2006, 00:24
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By the way, swim found a-MT to be one of the best anti-depresents ever used. For a year period in the mid 90's swim used 2mg of a-MT every morning as an anti-depresent and it was the best treatment for depression sysmptoms swim ever tried. to this day, daily depression hasn't been a problem either, but if it becomes a problem again swim will not hesitate to use a-Mt to treat again.
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Old 23-02-2006, 01:12
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Swimmer, Nagognog2 was referring to a-ET, not a-MT, which has a much higher dosage level. 150mg of a-ET is quite within the norm for the substance.
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Old 23-02-2006, 01:12
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whoops, meant snapper.
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Old 04-05-2006, 08:50
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Quote:
Originally Posted by Pinkavvy
By the way, swim found a-MT to be one of the best anti-depresents ever used. For a year period in the mid 90's swim used 2mg of a-MT every morning as an anti-depresent and it was the best treatment for depression sysmptoms swim ever tried. to this day, daily depression hasn't been a problem either, but if it becomes a problem again swim will not hesitate to use a-Mt to treat again.
Yeah, I've found 5mg a day to be far better than clinical dose of a tricyclic (lofepramine) for treating SAD... & it doesn't interfere with the libido like SSRI's do
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Old 04-05-2006, 20:35
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Cool

Quote:
Originally Posted by Richard_smoker
It was banned in the US with BZP and Foxy.
Actually it was AMT and 5-meo-DiPT. BZP TFMPP and 2C-T-7 were two years earlier.
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Old 05-05-2006, 18:23
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Quote:
Originally Posted by Nagognog2
MAOI's are to be respected. Saying something is a "negligable" MAOI is like saying something is a little bit fatal. Always follow the full set of don'ts when working with any MAOI. Bongo got off easy with an 8 hour migraine while in a highly accentuated state of awareness. NOT suggested. He also knows a chimp who mixed a benzodiazepine with a-Ethyltryptamine to help the monkey get some sleep. That chimp landed in an emergency room in a hypotensive crisis. Read: His blood pressure fell through the floorboards and the chimp passed out cold. a-ET is also reported to be a "mild" MAOI.

Consider your jellyfish warned.

I think that the migrane was more likely to have been due specifically to the beer alone (or in a combination with something other than AMT). It's not a fallacy to be able to classify some drugs with MAOI activities as being negligable in respect of interactions as the main factor when it comes to competetive/reversable MAOIs is the dose taken (or more accurately the plasma concentration of the drug). While a compound may show inhibition in vitro, the concentration required for inhibition (IC50 value) might be many many times that produced by an active dose of the compound. AMT is one of those as while it is an MAOI, the concentration required for 50% inhibition is so high that it would require the consumption of grams of the compound - a very unlikely situation when you consider an average dose is 20-40mg. Tecnically, amphetamine is a competetive MAOI, but before you'd get anywhere near the plasma concentration that would make it a problem, you'd have ODed and died from hyperthermia.

The above does not apply to non-competetive/irreverible MAOIs (the old MAOI drugs that used to be used as antidepressanrs, like phenelzine) as one they bind to the enzyme, it's perm. out of the game
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Old 07-05-2006, 04:04
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I havn't tried it myself but I know of quite a few people that said me they enjoyed it a lot, describing amt as a compound providing an lsd like mind opening but with no or little visuals, and very euphoriant & good mood (party drug)...probably really worth trying.

any 4-aco or 4-ho derivative for this one?
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Old 07-05-2006, 07:27
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AMT is truely unique in its effects, and is a true empathogen in league with MDMA, but with a distinctly speedier and has a more psychedelic feel. Is much more euphoric than many other psychedelics, yet its hallucinogenic and ++++ inducing effects are second rate. Those looking to nurture these effects were the ones who ended up not liking this compound. SWIM has always counted it as amongst SWIMs favorites, though long gone from the scene and likely will remain a memory at this point. Was a great compound for those long lasting parties!

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Old 09-05-2006, 01:15
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I can assure you it is most certainly still doing 'the rounds' . It just lasts too long for my liking. Up to about 8 hours is my sort of chem, anything upwards is just taking the biscuit.
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Old 20-05-2006, 05:59
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^ That's because you're in the UK, where AMT isn't a controlled compound (as of yet), so there's no laws being broken by synthesizing it, possessing it etc. It appears to be controlled in a lot of other countries (probably following the American control of it), including a lot of the ones that are still sources for RC's.

Personally, I pray that the UK government continues to overlook this compound for as long as is possible as it's absolutely marvellous
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Old 28-06-2006, 08:01
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JumpinJackFlash,

DON'T INCRIMINATE YOURSELF! Check the forum rules and edit your post.

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