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Benzodiazepines All about benzodiazepines (downers)

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  #1  
Old 02-03-2011, 04:26
RubyHollywood RubyHollywood is offline
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Snorting Valium?

Is this possible? Has any SWIYs tried this? My Alleycat is curious about it & if it's even worth it or is taking it orally the best way.....TIA
  #2  
Old 02-03-2011, 05:00
professor1165 professor1165 is offline
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Re: Snorting Valium?

Complete waste. The bioavailabity is so low and Valium is not water soluble, so only a minimal amount will be absorbed in the nasal cavity. You may as well flush it down the toilet. You will get some effect, with a nice punch, but it wont last and will be a minimal effect AT BEST. The most effective way to take any Benzo is sublingual. Put it under your tongue and let it dissolve (dont swallow!!) it takes practice but once you get used to it its a no-brainer. Its best for two reasons. 1). The membranes under your tongue absorb the drug much faster than having it pass through your digestive tract so it hits faster. 2). Since your bypassing the digestive tract entirely, nearly 100% of the active ingredient reaches your brain. When eaten, bits and pieces are left all over your body; in your stomach lining, in your liver; in your intestinal lining. By letting it dissolve under your tongue nearly all of the drug goes directlly to the brain, no waste. SWIM always goes sublingual, NEVER snorts or eats benzos.

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  #3  
Old 02-03-2011, 14:16
PsychoActivist PsychoActivist is offline
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Re: Snorting Valium?

Quote:
Originally Posted by professor1165 View Post
Complete waste. The bioavailabity is so low and Valium is not water soluble, so only a minimal amount will be absorbed in the nasal cavity. You may as well flush it down the toilet. You will get some effect, with a nice punch, but it wont last and will be a minimal effect AT BEST. The most effective way to take any Benzo is sublingual. Put it under your tongue and let it dissolve (dont swallow!!) it takes practice but once you get used to it its a no-brainer. Its best for two reasons. 1). The membranes under your tongue absorb the drug much faster than having it pass through your digestive tract so it hits faster. 2). Since your bypassing the digestive tract entirely, nearly 100% of the active ingredient reaches your brain. When eaten, bits and pieces are left all over your body; in your stomach lining, in your liver; in your intestinal lining. By letting it dissolve under your tongue nearly all of the drug goes directlly to the brain, no waste. SWIM always goes sublingual, NEVER snorts or eats benzos.
Sublingual for Benzo's should not be any more effective than swallowing the pill. Sublingually, drugs are absorbed through the mucous membranes, very similar to insufflation. Most benzo's, as you have already stated, have a very low bioavailability when used through the mucous membranes as they are not very soluble through this ROA. In short when you use them sublingually, the only effect you get from them is by the melted pill being swallowed through saliva. Same thing with when they are snorted... it goes into ones nose, they get the drip, swallow it, and it's digested through the stomach.
  #4  
Old 02-03-2011, 14:57
NeuroChi NeuroChi is offline
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Re: Snorting Valium?

Diazepam is a weak base, pKa of 3.0, and as a result, is highly unionized (its more lipid soluble state) in the stomach, which gives it a 100% oral bioavailablilty according to some sources. Just eat it.
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Old 02-03-2011, 17:50
Piglet Piglet is offline
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Re: Snorting Valium?

If you snort it, it just runs down your neck & gets absorbed by the stomach. Now, plugging diazepam is effective - just not classy.
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Old 02-03-2011, 18:12
Jatelka Jatelka is offline
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Re: Snorting Valium?

UTFSE

This has been covered so many times before, it's getting boring
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diazepam, drug, drugs, drugs forum, plugging, snorting, snorting drugs, solubility, valium

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