LSA-huaska?

[a-SalviaLover]

Is it possible to combine safely HBWR seeds with a MAOI? Would the intensification be similar to that of shroomz?

[ChemicallyBound]

BE MOST CAREFUL!!!!!!!

I would be very hesitant of ergolines and MAOI'S!

they are both extremely potent in small doses, if you must then start out with the smallest dose and do incremental steps

Reputation Comments on this post:

good looking out ~pa

[Pinkavvy]

Swim agrees with chemically bound, maoi's can be dangerous especially when combined with something that is active in such small ammounts.

[Alfa]

I would not dare to try that.

[a-SalviaLover]

I use pharmaceutical MAOIs (moclobemide). It has the least side effects, doesn't require any special diet. Doesn't alter the trip, just cuts the dose half, sometimes even three times. I've tried it with shroomz and 5-meo-dipt. Didn't have any problems, although my girlfriend puked on 5-meo-dipt. I'll probably try this combination and post here what happened.

[Emperiorjack]

It would be interesting if someone's mouse had a go at this idea.

[Alfa]

Originally Posted by a-SalviaLover

I use pharmaceutical MAOIs (moclobemide). I've tried it with shroomz and 5-meo-dipt.

Did you try this with a oral dose of Salvia?

[raven3davis]

SWIM would recommend against this. LSA lasts a long time and it quite potent allready. Just a few seeds will significantly alter the trip so if you are looking to trip harder just increase your dose by a few seeds.

[a-SalviaLover]

MAOI is cheaper than HBWR around here. And it will reduce the nausea to some degre, if the potentiation actually works. Don't have time to try the combo, unfortunately.

I've used MAOI with Salvia once, but then I had take mushroomz, too, so I can't say how it alters the trip. It shouldn't potentiate Salvia's effects (salvinorin is not an amin compound), but many people say it actually does.

[genaro]

LSA = depressant

mixing with MAOIs will quite possibly cause acute repiratory depression which might lead to death by suffocation within a short period of time.

Of course, everything is a matter of dosage so if you do try such a dangerous combo despite my warning, then I STRONGLY suggest you take very little MAOI (like 3g harmala seeds) with very little hbwr (2 seeds no more for your first attempt)

[kemistudent]

I've used MAOI with Salvia once, but then I had take mushroomz, too, so I can't say how it alters the trip. It shouldn't potentiate Salvia's effects (salvinorin is not an amin compound), but many people say it actually does.

As Alfa asked, did you take the salvia orally with the MAOI, as one would when they want to make DMT active orally?

[fatal]

isnt it also possible that other chemicals other than the lsa in woodrose could combine negatively with the maoi? not specifically sure on their chemical makeup as far as that but it does seem to give a good amount of toxic reactions in the first place. maybe ramping that up wouldnt be so good? although swim tells me he never personally had any negative effects from the hbwr he says the character is different from morning glories... more confusing

[Nagognog2]

Ergotamine acts as a powerful vaso-constrictor - hence it's use in migraines - so it's quite possible other lysergic acid derivatives do so also. Possible. So I would suggest extreme caution with a combination with a MAOI. It may be groundbreaking research - but you don't want them doing the groundbreaking with a shovel to fit a rectangular box.

[genaro]

hbwr and mg seeds and ololiuqui contain lysergic acid amines (LSAs)...note the plural.

These are:
Ergine (aka LA-111, commonly called LSA which is somewhat eroneous as there are many LSAs)
Isoergine
Ergometrine
Lysergic alpha-OH-ethylamide
IsoLysergic alpha-OH-ethylamide

All are psychoactive but let's assume that the ones responsible for the most part of the psychedelic effect are ergine and isoergine (which are both present in much more significant quantities than the three other ones which are just adding a little effect to the whole thing)

ergine and isoergine are depressants so here there's a big risk combining these with MAOIs (respiratory depression as said)...now I don't know about the other ones excepting ergometrine which is a powerful vaso-constrictor which can also be a serious concern if combined to MAOIs. Ergometrine is almost as potently vasocontrictive as ergotamine, active in submilligram doses, and even if it's not present in big enough quantities to induce ergotism like gangrene there's still enough of it in the seeds to produce some noticeable vasoconstriction (blue lips, numbness of extremities, pain in the legs, etc have been reported, these symptoms beeing quite probably produced by this vasoconstrictive alkaloid).

So combining MAOIs to LSAs containg seeds can be very dangerous (because these contain both depressant and vasoconstrictive substances), therefore, as I suggested in my previous post, if you choose to go for it start very low and increase dosage very progressively (and no alcohol at all !!!)

[mirela]

hello, sorry to unburry this thread but i was wondering what is huaska, google it but with no results

[Alfa]

The concept discussed in this thread is a variation of ayahuacsa. Ayahuasca combines psychedelic plants (most frequently containing n,n,-DMT) with a MAOI (often harmala seeds). The MAOI enables the DMT to become an active drug. A MAOI can potentate drugs as well.

In the case of LSA there is a large risk involved because LSA has several toxicity & pharmacological issues.