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Concerta & Ritalin About Methylphenidate.

 
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  #1  
Old 11-12-2010, 22:30
eddie eddie is offline
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How much Ritalin/Methylphenidate is too much?

Hello I had a dream about my friend having a dream where he was watching a movie the main character was a guy named SWIM in this movie SWIM asked his friends this question. how much do you need to snort to OD.SWIM knew he was not going to OD, but SWIM was just worried and wanted to know for the future. Before the movie SWIM said thank you to every that helps him gain the knowledge that he wants to know. Then my dream ended.

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Please try to use a more descriptive subject without slang or abbreviations next time.
  #2  
Old 11-12-2010, 22:48
Wanderer Wanderer is offline
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Re: How much Ritalin / Methylphenidate is to much?

From the Drugs Forum Wiki on Methylphenidate, the various LD50's are listed here:

Methylphenidate - Toxicity

While this doesn't list the dose for humans, it does, Mr. Hamster believes states that the LD50 for rats and mice is between 40-50mg/kg when injected IV.

Insufflation would be fairly close to IV, but a bit less efficient depending on the sinus conditions. Both routes bypass first pass metabolism by the liver.

A responsible hamster would never want to try to get anywhere near the LD50 of any substance.

However, the normal dose for the IR formulation taken orally is typically 10-20mg.

Given this, one could say that 10-20mg insufflated might be safe, but every hamster and chinchilla are different. So the best advice is to start small if taking medications in a nonprescribed manner and always remember one can always take more, but can never untake what's been taken.

Also, take a look at this thread, this is a subject which has been discussed before:

Ritalin dosage (snorted)

Be safe, be well...

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Really good info, covers a lot of bases.

Last edited by Wanderer; 11-12-2010 at 23:54. Reason: found another thread with similar subject
  #3  
Old 18-12-2010, 06:00
sadskills1987 sadskills1987 is offline
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Re: How much Ritalin/Methylphenidate is too much?

LD50's aside, SWIM's poo flinging monkey in a dream (SPFMIAD) said that the amount SWIY's nose is clogged has a whole hell lot more to do with bioavalibility. in any case, ritalin psychosis, which SWIY seems to have, according to SPFMIAD, wears off not as quick as SWIY would hope, but seeing as this post was written about week ago, please allow SWIY to look retrospectively on the whole experience and evaluate whether his/her experience was really worth the deafening paranoia. if SWIY does some soul searching, this psychotic episode must have been a pretty powerful lesson. HIGH DOSES OF METHYLPHENIDATE CAUSES PSYCHOSIS!!! (not going generally 'off the farm' but definitely paranoid thoughts).
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Old 18-12-2010, 06:18
Wanderer Wanderer is offline
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Re: How much Ritalin/Methylphenidate is too much?

What critter mentioned psychosis?

The OP was wanting to know how much was too much, and never mentioned psychosis.

Intranasal, or insufflation has many variables associated with it including viscosity of mucosa, pH, the condition of the nasal epithilium, etc.

For more information on intranasal ROA, the poo flining monkey should have a look at this thread in the Pharmacology Forum:

Nasal Drug Delivery System-Factors Affecting and Applications

It's down to more than just one's nose being clogged which can easily be remedied.

Psychosis, is a whole other story and is associated with the abuse of psychostimulants in general, but not what the OP was looking for.

Be well...
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Old 18-12-2010, 07:18
SamanthaRabbit SamanthaRabbit is offline
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Re: How much Ritalin/Methylphenidate is too much?

At doses higher than 20mg instant release my rabbit experiences anxiety, nausea, and intestinal disturbances.
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Old 18-12-2010, 07:34
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Re: How much Ritalin/Methylphenidate is too much?

Quote:
Originally Posted by SamanthaRabbit View Post
At doses higher than 20mg instant release my rabbit experiences anxiety, nausea, and intestinal disturbances.
Mr. Hamster wonders what 360mg would do to the poor bunny, he shudders to think.

The hamster is curious about the intestinal disturbances experienced with doses greater than 20mg of the IR formula, and would assume it is worse if the dose is increased?

Be interested, be well...
  #7  
Old 21-12-2010, 04:31
SamanthaRabbit SamanthaRabbit is offline
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Re: How much Ritalin/Methylphenidate is too much?

Quote:
Originally Posted by wanderer View Post
Mr. Hamster wonders what 360mg would do to the poor bunny, he shudders to think.

The hamster is curious about the intestinal disturbances experienced with doses greater than 20mg of the IR formula, and would assume it is worse if the dose is increased?

Be interested, be well...
Methylphenidate in general causes extreme intestinal disturbances for my rabbit, more so Ritalin IR than Concerta XR.

My rabbit performed a test over Thanksgiving break and didn't take her methylphenidate because she didn't have work or school responsibilities and her system kind of corrected itself.

Now that my rabbit is taking Concerta a few days a week again it is irregular again, to the point where she may have to look for another medication all together It however, isn't as severe as when she would take Concerta in the morning and Ritalin at 4pm.

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addiction, concerta, drugs-forum, ethylphenidate, insufflated, insufflation, ld50, methylphenidate, methylphenidate dose, methylphenidate insufflation, overdose, ritalin, ritalin addiction, ritalin dose, ritalin insufflation, snorting, snorting drugs, snorting methylphenidate, snorting ritalin

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