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Phenethylamines Phenethylamines and amphetamines.

 
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  #1  
Old 27-10-2010, 23:51
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25C-NBOMe (NBOMe-2C-C) Drug Info

Please post any info about 25C-NBOMe here. I will comment on swim's research with this soon.

Can anyone add information about:
names / synonyms
molecule
dose
duration
side effects
legal status
have there been any reported incidents with this compound?
since when has this research chemical been available?
stability of the molecule / compound

Names: 25C-NBOMe
Synonyms: NBOMe-2C-C
IUPAC: 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine



Experiences with 25C-NBOMe should be discussed here.
Attached Images
File Type: jpg 25c-nbome.jpg (3.0 KB, 1786 views)

Last edited by Terrapinzflyer; 28-10-2010 at 06:38. Reason: add molecule
  #2  
Old 28-10-2010, 06:48
Stephenwolf Stephenwolf is offline
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Re: 25C-NBOMe

Since when has this been available: I noticed it for the first time early September.

Oh, and Dosage: What I've read on it (not a lot) 250ug is a bit underwhelming, 300ug is decent. The experience being relayed to me soon, will be of 300ug, so I'll report back about if thats an OK standard dose. The small multitude of individuals mentioned in the anonymous letter, will probably give a good idea of how variable the effects are between people. Its also a nicely varied group, 3 males, ranging in weight at 170, 155, and 125lbs. and a female weighing 115 or so. It'll give a good idea what 300ug is for different weights, and between males and females. (or if it doesn't change anything at all)

Have read of a person who used around 325ug claiming it as a ++ occasionally flirting with a +++

Duration: the 325ug guy described it as so : lasted for around 8-10 hours. About a 2 hour long come up followed by a 3-4 hour plateau and then a gradual come down. Sleep was easily achieved ten hours later

Last edited by Stephenwolf; 28-10-2010 at 06:58. Reason: Dosage information to add.
  #3  
Old 30-11-2010, 14:39
sigmundfreuid sigmundfreuid is offline
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Re: 25C-NBOMe

What are the methods of administration ?
Vaporization
Oral
Nasal

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Please expand information on this subject, posts like this aren't too useful with out backing.
  #4  
Old 30-11-2010, 15:16
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Re: 25C-NBOMe

Same as 25D-NBOMe it is active sublingually and not orally as far as I know. Be aware. Be safe.


  #5  
Old 23-03-2011, 20:01
Internal Confusion Internal Confusion is offline
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Re: 25C-NBOMe

SWIM read on another board that sub-lingual is working but by far not be best ROA.

Sounds like liquid dosing through the Nose is the way to go.

SWIM found an assay in the Net, the guy that wrote it had the idea that this ones salt form could be used in a nasal spray for dosing..... maybe lets say 100g per spray.... anyone thinking that this may work ?

The other Idea he had, was to use the Nasal spray or an ansthma inhalter to spray it direktly into the lungs. Could that be potentially dangerous or even working ? seems like the easiest way to go he thought ?


What do SWIMMERS think ?
  #6  
Old 24-03-2011, 04:32
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Re: 25C-NBOMe

It might work transdermally. That would without a doubt be the easiest way to administer it.
  #7  
Old 19-04-2011, 19:01
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Re: 25C-NBOMe

Even in samples that have been at room temperature for months there is absolutely no sign of decreased potency. This compound is probably sustainable for a long time under the right conditions, like other phens.



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Nice data on long term 25C-NBOMe storage.
  #8  
Old 22-04-2011, 02:32
squeezix squeezix is offline
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Re: 25C-NBOMe

Come on Fatal, tell them what you told me....You know buddy, the one infraction I ever had here and will ever have was a mixed blessing as it brought us to becoming pals....

But yeah, tell them what you told me about solubility and dosing.

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Adds nothing to the thread. If you already have information why not just share it?
  #9  
Old 22-04-2011, 11:28
psychedelaholic psychedelaholic is offline
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Re: 25C-NBOMe

I've tried 25C-NBOMe twice. First time was absolutely insane and probably the scariest and one of the strongest trips I have ever had. Second time was with a much lower dose and was fairly mild but still enjoyable.

Names/synonyms Boom, C-Boom

Insufflated dose: (from my experience and others I have talked to)

Active from as little as 50ug probably even less.

Light - 50-200ug
Mild - 200-350ug
Strong - 350-800ug
Very strong - 800ug-1200ug
Insanity - 1200ug+ (I think the strong dose I took was around 1500-2000ug)

My trip report:
http://www.drugs-forum.com/forum/sho...9&postcount=28

It can be taken orally, sublingually, nasally, intramuscularly and intravenously (with increasing potency) Insufflated it is easiest to add to water and drop up the nose.

Insufflated - Come-up, duration etc:

First signs within 5mins. With my big dose first signs came on in under 60seconds. Takes 15mins to peak. Peak lasts 3 hours. Then comes down over the next 3-8hours (depending on dose) Sleep is easy once it has worn off.

Effects:

Big dose:
Ego loss, loss of self, super-imposed imagery, strong auditory effects, crazy colourful visuals, utter terror combined with beautiful insights, massive time distortion, paranoia, never-ending inescapable thought loops

I had little nausea from it which suprised me, the body load coming up was fucking intense though and pretty uncomfortable. Like having lightning bolts shoot through and out you.

Mild dose: (350-400ug)
Mild euphoria, visual disortion, softening of focus, ease of conversation, floaty body high, slight nausea (wierd)

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Concise and well written report. This substance sounds like a keeper.
New and important data, specially the tentative dosages and effect duration.

Last edited by psychedelaholic; 22-04-2011 at 11:33.
  #10  
Old 02-05-2011, 02:32
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Re: 25C-NBOMe

Quote:
Originally Posted by psychedelaholic View Post
Active from as little as 50ug probably even less.

Light - 50-200ug
Mild - 200-350ug
Strong - 350-800ug
Very strong - 800ug-1200ug
Insanity - 1200ug+ (I think the strong dose I took was around 1500-2000ug)
That is fairly accurate. It definitely gets strong at >1mg doesnt it? This of course will vary greatly with your ROA and the method by which you are ingesting the compound. Via inhalation the effects are felt very rapidly.


  #11  
Old 05-05-2011, 15:55
Rage Rage is offline
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Re: 25C-NBOMe

Ive got a sample coming and its on a blotter, im guessing this will be fine to dose with it has 350mcg on, so its a medium dose, dont wanna start to high lol,

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does not add to the thread at all
  #12  
Old 14-05-2011, 21:48
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Re: 25C-NBOMe

SWIM will be trying this next and is wondering how hard it is to fall asleep on after said peak and duration. How stimulating is it compared to 2c-c?
  #13  
Old 18-05-2011, 03:48
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Re: 25C-NBOMe

It is not very stimulating. YMMV

  #14  
Old 18-05-2011, 19:08
psychedelaholic psychedelaholic is offline
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Re: 25C-NBOMe

It is more stimulatioing than 2CC by a lot but is less stimulated then DOC. At least in my experiences
  #15  
Old 23-05-2011, 20:29
smogzahoy smogzahoy is offline
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Re: 25C-NBOMe

Quote:
Originally Posted by psychedelaholic View Post
It is more stimulatioing than 2CC by a lot but is less stimulated then DOC. At least in my experiences
Thanks a lot this is very reassuring, I will have some downers ready but I am not to worried now by excessive stimulation. I will post trip report by this weekend.
  #16  
Old 24-05-2011, 17:05
geezaman Gold member geezaman is offline
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Re: 25C-NBOMe

Does anyone have information regarding;
- Any difference in potency of the HCL salt versus the freebase form of this chemical.
- The temperature at which the freebase form degrades.
- Possibility of successfully dosing the freebase via sublingual or insufflation (from what he has read he not think this is possible.)

Snufkins current idea is to dissolve 10mg of 25C NBOMe freebase in 30ml 99.9% isopropanol and then to dry 1ml "doses" (300ug) onto plant matter to be smoked in cigarettes/spliffs/pipes.

Geezaman has been unable to locate hardly any information on the freebase form of this chemical, although a single post on another website did state "vaporisation beats insufflation by far".

Awaiting your advice


G
  #17  
Old 01-07-2011, 07:19
Stephenwolf Stephenwolf is offline
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Re: 25C-NBOMe

I'd like to know the time-frame with vaporized. If you ever hear from someone who tries this.
  #18  
Old 01-07-2011, 07:24
psychedelaholic psychedelaholic is offline
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Re: 25C-NBOMe

I have 100ug left in a vial which I could dry out and try it with. Might do it tonight since I got a half day at work
  #19  
Old 30-07-2011, 19:01
psychedelaholic psychedelaholic is offline
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Re: 25C-NBOMe

Didn't try vaporizing but do have 1000ug left which I will be taking orally tonight. Not tried oral dosing with it yet so will see how it goes. Report will be written as per usual of course. Or will try 500ug sublingual not decided yet.
  #20  
Old 02-08-2011, 13:35
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Re: 25C-NBOMe

My Alien Roger will shortly be receiving some 25C-NBOMe (355mcg) & 25D-NBOMe (850mcg) on blotters. He has read on the 25D-NBOMe threads that people have found that buccal is a more successful than sublingual.

Roger would presume that the same would apply for 25C? Or is it really just a better idea to go for liquid insufflation? If so Roger has read some methods for transferring the material into liquid from freebase or HCl, but can you do this in the same manner when the 25C-NBOMe is already on a blotter?
  #21  
Old 21-08-2011, 02:37
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Re: 25C-NBOMe

If swij had 10mg of 25c-nbome in salt form what would be the best way to go about measuring a 400microgram dose out. Swij assumes dissolving it in water would be the way to go (not sure but since its hcl form would assume so) but wonders how long this solution would last? If swij wanted to dissolve all 10mg how much water would he use to get 1ml=400mics? Sorry if this is a simple math equation but swij would suppose it depends on what youre dissolving no? At any rate swij is terrible at math and just want to be safe. Any help would be greatly appreciated!
  #22  
Old 21-08-2011, 03:48
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Re: 25C-NBOMe

Quote:
Originally Posted by Jerc View Post
If swij had 10mg of 25c-nbome in salt form
First off it's important not to make assumptions about the mass of material one is working with. Based on the tone of this post I'm going to take a wild guess that the person in question does not own a suitably sensitive scale and is assuming that they have 10mg because this is what they ordered and/or what it says on the packaging.

Would this be the case? If so then it's essential not to take such assertions on good faith. Vendors routinely send out the wrong amount and in some cases the amount they send is way more than expected. It's impossible to discern 10mg by eye so it might be substantially more than 10mg. If this were the case then the calculations would be way off and the person would overdose. When working with a drug that's active in the microgram range that overdose could easily be a fatal one.

Quote:
what would be the best way to go about measuring a 400microgram dose out. Swij assumes dissolving it in water would be the way to go (not sure but since its hcl form would assume so) but wonders how long this solution would last?
Yes volumetric measurement is certainly the way to go for handling such small quantities but to do this accurately it is still essential to weigh out the substance on an accurate scale to begin with.

Water would seem like the most suitable solvent for intranasal use. For longer term storage in water it is best to aliquot out individual doses, freeze them separately then thaw out the required doses as necessary. Freezing will slow the rate of degradation/spoiling. There are three reasons for aliquoting out individual doses rather than freezing the solution as one batch; (1) convenience, (2) it avoids repeated freeze/thaw cycles that may accelerate degradation of the drug, and (3) volumetric changes can occur even in frozen solutions (especially with small volumes) and this has a concentrating effect. By measuring out the individual doses prior to freezing one could never take more of the drug than they were expecting.

For sublingual use 40-50% ethanol (e.g. vodka) might be a better choice as the alcohol spoils less easily than water. For storage here it would be better to lay the solution onto blotter, though doing this consistently is quite an art in itself.

Quote:
If swij wanted to dissolve all 10mg how much water would he use to get 1ml=400mics?
1) Weigh out the starting material on a suitably sensitive scale. One that is accurate to 0.001g (1mg) should be suitable in this case. In my example the person in question thought they'd been sent 10mg of 25C-NBOMe but in fact the substance weighed out as 0.030g (30mg or 30000g).

2) They want a final solution of 400g/mL 25C-NBOMe. 30000g / 400g = 75. They'd therefore need 75mL solvent to make a solution with a final concentration of 400g/mL 25C-NBOMe.

3) Using suitably accurate glassware (an 100mL measuring cylinder with markings every 2mL) they measure out the appropriate volume of solvent and add it to the drug in a sealable container. They then mix thoroughly by inversion to ensure that the drug fully dissolves. It is absolutely critical that the drug dissolves completely and does not form a suspension. If the drug does not dissolve completely then the concentration of the solution will not be homogenous.

4) They measure out the volume of solvent again to check that mixing the drug into the solvent did not cause a change in volume. This would not be expected with most drugs, but in some cases a cutting agent might elicit a volume change. Had the volume doubled to 150mL after adding the drug (highly unlikely!) then the effective drug concentration would've halved from the originally calculated 400g/mL to 200g/mL, so they would now need 2mL aliquots for a dose of 400g. In this case we'll assume that there was no change in volume so they did not need to recalculate the concentration of the drug solution.

5) They aliquot out 1mL doses of the solution using a 1mL syringe and transfer them into individual containers for freezing. Each 1mL aliquot is a 400g dose of the drug. Note that had they not bothered to weigh out the drug to begin with and assumed there to be 10mg then they would not have diluted the drug so far and each aliquot would contain 1200g of the drug; much more than they anticipated and potentially dangerous if they were to take multiple doses of it.

Quote:
Sorry if this is a simple math equation but swij would suppose it depends on what youre dissolving no?
No the calculation is not heavily dependent on the substance and solvent. The math involved is indeed quite straightforward. Without wanting to sound too patronizing if a person needs to ask how to do this calculation then they should not attempt to put it into practice unless there is another person on hand that is more comfortable with the math involved to check their working. If it's not something one does routinely then it's easy to make errors, especially when interconverting units from grams to milligrams to micrograms. These errors could make the end doses out by an order of magnitude or more and that is potentially lethal. Being 'terrible at math' isn't something that is worth dying for; get a second hand and watchful eye to ensure that nothing goes wrong.

Most importantly don't cut corners. It might be tempting to skip certain steps because if the necessary equipment is not immediately available, but this sloppy attitude has resulted in a number of RC-related injuries and deaths. The drug has to be weighed out on appropriately sensitive scales. The solutions have to be measured out with suitable gradiated equipment (measuring jugs/cylinders, graduated pipettes or syringes etc.).
  #23  
Old 21-08-2011, 23:38
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Re: 25C-NBOMe

Quote:
Originally Posted by Stephenwolf View Post
I'd like to know the time-frame with vaporized. If you ever hear from someone who tries this.

Via inhalation the onset of this compound is almost immediate.
  #24  
Old 22-08-2011, 05:12
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Re: 25C-NBOMe

Thanks phenoxide! Very informative. Swij has very little exp with rc's but this chem really caught his eye. swij must admit he was hoping to avoid the purchase of a scale but after reading your posts and several others realizes how disastrous this could be. Excitement of trying something new many times makes swij throw logic out the window but he has decided to hold off on experimentation with bulk material until proper equipment is acquired. Perhaps prepared blotters would be a safer route to satisfy swijs curiosity.

On a side note Swij believes he has read reports of swimmers taking 1mg+ of this rc. As this is a research chemical swij assumes not very much information is out there on this subject..but what would be the dangers of a large dose of 25c? other than a potentially overwhelming experience. Just curious of physical effects
  #25  
Old 22-08-2011, 06:43
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Re: 25C-NBOMe

One thing to take note of is to be careful when transferring/weighing the pure material. If proper precautions are not taken it is possible to easily expose yourself to an active dose or more.

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