It's quite effective so I hear. A fading flame told me this is how she did it with 30mg XRs.
She noted: A recent bowel movement or enema are ideal.
1] Open, crush thoroughly. She used a nitrous
charger and a candle holder as an improvised mortar and pestal (and glass and steel are slick, non-porous, both pluses).
2] No really. Thoroughly. Fluffy, mostly white, and completely free of crunching sounds.
3] Add water. Less is more, but just watch it. Use as much as SWIY needs to leave the mixture completely soaked.
4] Use a filter (micron, wheel, cotton ball, cigarette filter) and using a syringe (large gauge, large cc is ideal), suck up the filtered liquid. If there is more liquid than the syringe can hold, don't sweat it.
5] Now with filtered solution, options are had.
5a] If a nose, ear syringe or some similar device, it can be filled from the syringe. Size of the end must be noted (it is going in...). Lubricate if desired, insert, empty the liquid, withdraw and ta-da.
5b] Her preferred option was out of laziness, but with a benefit. She simply pop of the needle of the hypo and insert. If using the syringe again, clean it, come on, it's gross. A potential problem she'd run into is that she has more liquid than one, two, or however many full doses; more over a syringe without a needle sucks up through a filter far less well. However, with skill, she could suck a dose, plug it, and have another read. The benefit of this is it gave time to feel the dose come on, titration.
Note: she said that lying on the side opposite of your dominant hand is good position, as well as kneeling and bent forward.
She swore by it, suffering none of the negative associated with other routes of administration
(nasal destruction, clogged veins, namely) even with prolonged use. With a bioavailibility of 95% (she said, not to be sworn on); regardless, significantly than insufflation
or oral routes.
So, I hope that helps.