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Deliriant antihistamines Diphenhydramine, cyclizine and other antihistamines.

 
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  #1  
Old 11-09-2008, 18:34
RobJaw RobJaw is offline
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Hydrocodone + Diphenhydramine

Swim found a note that said the combination hydrocodone + Diphenhydramine can cause the opiate buzz to feel stronger and better. Swim was wondering if this is true?

Thanks!
  #2  
Old 11-09-2008, 20:18
PilL FreaK PilL FreaK is offline
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Re: hydrocodone + Diphenhydramine (?)

When SWIM tried Diphenhydramine on its own it was pretty intense and he got spasms in his legs.. When he laid down his legs kept kicking up. I wouln`t try that combination.
  #3  
Old 11-09-2008, 23:58
fiveleggedrat fiveleggedrat is offline
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Re: hydrocodone + Diphenhydramine (?)

At low doses, as in, under 50mg, some have reported increased CNS sedation and similar, but decreased itching.

Anything over 100mg is asking for a delirious, lousy opiate high.

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good advice
  #4  
Old 12-09-2008, 07:08
Zaknafien Zaknafien is offline
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Re: hydrocodone + Diphenhydramine (?)

how much hydrocodene would swim have to take in combination to receive the increased high and how strong is the high? A quick answer would be appreciated as swim intends on doing this soon.
  #5  
Old 12-09-2008, 16:24
fiveleggedrat fiveleggedrat is offline
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Re: hydrocodone + Diphenhydramine (?)

Take a little less than usually. Just use common sense when dosing. If you make a dose of say, 40mg stronger, you might want to reduce it to say, 30mg. Personal preference comes in here too.
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Old 12-09-2008, 23:17
Zaknafien Zaknafien is offline
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Re: hydrocodone + Diphenhydramine (?)

haha good lord 30mg? Swims at 15mg ^.^. And is the high alot different then each by its self? cause swim don't much like diph all that much but hydrocodien he does.
  #7  
Old 13-09-2008, 00:01
RobJaw RobJaw is offline
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Re: hydrocodone + Diphenhydramine (?)

a note from ganny said this "

SWIM tripped so hard last night. SWIM did a 30 mg and about 800 diph... omg.. It was scary cause SWIMS dad was yelling at SWIM and telling SWIM to get out of the house and the ride is on its way to come pick me up! it was so freaken real... so SWIM went to my bedroom so depressed haha... and a few hours ago I found out that my dad was here a week ago... and my mom didnt even talk to me last night... but OMG They totally freakn did if you know what SWIM means. BTW Swim realized that the DRUG becomes magic at night! In the day time its not so trippy but when the sun goes down!!! OMG!! "
  #8  
Old 13-09-2008, 01:08
purplehaze Gold member purplehaze is offline
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Re: hydrocodone + Diphenhydramine (?)

Quote:
dihydromorphinones include but are not limited to:


hydrocodone


codeineone


hydrmorphone


oxycodone


oxymorphone


Diphenhydramine (Benadryl) -- This antihistamine increases the effects of opiates more or less evenly across the board, and the effect seems to be similar for all natural and semi-synthetic opiates. A normal dose of the opiate can be taken with 25 to 75 mg of diphenhydramine. This mixture should be taken with a bronchodialator/decongestant because diphenhydramine is also a cough suppressant. The green label version of Alka Seltzer cold medicine contains a sufficient dose of decongestant and sodium bicarbonate (which slows metabolism). If the diphenhydramine product contains alcohol, the loading dose of the opiate should be reduced by 30% and the any booster doses should be taken no sooner than an hour afterwards.
Those who take larger doses of antihistamines or other anticholinergics for the euphoriant properties should not take opiates along with them; needless to say, the mixing of opiates with the much higher deliriant doses of anticholinergics can be assumed to invariably have catastrophic effects because of the combination of respiratory depression and thickening of bronchial secretions caused by these drugs. It is assumed that any dose of diphenhydramine above 125 mg cannot be safely mixed with any quantity of opiate.


This is the thread you want.
http://www.drugs-forum.com/forum/sho...iating+opiates
  #9  
Old 17-09-2008, 21:13
cra$h cra$h is offline
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Re: hydrocodone + Diphenhydramine (?)

a lot of people will pop a benadryl (diphenhydramine) or 2 with opiates to get better nods, and stop the itchies. It does stop the itchies though, as long as the dose (of diphen) is low.
  #10  
Old 19-09-2008, 13:46
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Re: hydrocodone + Diphenhydramine (?)

Quote:
Originally Posted by PilL FreaK View Post
When SWIM tried Diphenhydramine on its own it was pretty intense and he got spasms in his legs.. When he laid down his legs kept kicking up. I wouln`t try that combination.
Diphenhydramine is known to cause/worsen Restless Legs Syndrome (RLS) in those who suffer from it or are prone to it. This girl I know found diphenhydramine seriously worsened her RLS but only while on it, the next day she was fine.

Combining it with hydrocodone might actually reduce or cancel out the RLS as opiates are often used to treat it.

For most people RLS is not an issue though. Pill Freak, I would suggest getting your iron/ferritin levels checked and if these are fine and you have more frequent issues with your legs then do some research into RLS as it is a complicated illness.
  #11  
Old 05-10-2008, 01:21
RobJaw RobJaw is offline
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Re: hydrocodone + Diphenhydramine (?)

Quote:
Originally Posted by ~lostgurl~ View Post
Diphenhydramine is known to cause/worsen Restless Legs Syndrome (RLS) in those who suffer from it or are prone to it. This girl I know found diphenhydramine seriously worsened her RLS but only while on it, the next day she was fine.

Combining it with hydrocodone might actually reduce or cancel out the RLS as opiates are often used to treat it.

For most people RLS is not an issue though. Pill Freak, I would suggest getting your iron/ferritin levels checked and if these are fine and you have more frequent issues with your legs then do some research into RLS as it is a complicated illness.
SWIMS has tested this and the combo does make it much Funner! and there is almost no restlessness at all!

2 x Norco 7.5 with about 800 mg diph
  #12  
Old 05-10-2008, 01:25
fiveleggedrat fiveleggedrat is offline
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Re: hydrocodone + Diphenhydramine (?)

Quote:
Originally Posted by RobJaw View Post
SWIMS has tested this and the combo does make it much Funner! and there is almost no restlessness at all!

2 x Norco 7.5 with about 800 mg diph
That has to be a joke.
  #13  
Old 05-10-2008, 01:33
RobJaw RobJaw is offline
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Re: hydrocodone + Diphenhydramine (?)

Quote:
Originally Posted by fiveleggedrat View Post
That has to be a joke.
Note from Grandma ol'roy

Negative! SWIM believes some people can do this... others can't. When SWIM first did this... SWIM did get very restless it was un-enjoyable... but over time SWIM has to make do... with what SWIM can get sadly... Especially latly because SWIM was in a horrible accident and now SWIM has 16 screws and 3 plates in SWIMS hip along with a broken lower back.
  #14  
Old 05-10-2008, 03:42
fiveleggedrat fiveleggedrat is offline
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Re: hydrocodone + Diphenhydramine (?)

Why in the world would someone take 800mg? Most people get delirious off 300mg, not to mention the unpleasant side effects of antihistamine overdose.

Anything over 75, perhaps 100mg is completely pointless for increasing the effects of the opiate.
  #15  
Old 05-10-2008, 04:17
tryptamaster tryptamaster is offline
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Re: hydrocodone + Diphenhydramine (?)

yea dude ur "trippy" effects were jsut a fucked up delerious high. thats liek drinkin 30 beers to potentiete 1mg clonazepam. ur jsut gonna be drunk haha.
  #16  
Old 22-12-2008, 06:30
spaceyjake spaceyjake is offline
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Re: hydrocodone + Diphenhydramine (?)

swim just tried out this combination and so far it is working out really well
  #17  
Old 22-12-2008, 07:39
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Re: hydrocodone + Diphenhydramine (?)

You're not tripping from the hydrocodone, you're tripping from the benadryl!!! Benadryl is a deleriant like datura!!!
  #18  
Old 27-12-2008, 09:03
RaverHippie Gold member RaverHippie is offline
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Re: Hydrocodone + Diphenhydramine

Again, this combination is meant as a recommendation for a small amount of diphenhydramine (max 50mg) to increase the potency of someone's normal opiate dose. That is the general consensus and is usually discussed in the opiate forum like the link that purplehaze mentioned.

Now, RobJaw is onto something interesting since the more awful parts of the deliriant high include the RLS-like symptoms which Lostgurl mentioned. If a recreational dosage of diphenhydramine (300mg+) is combined with an opiate of some sort, possibly the deliriant high will be even more enjoyable than it currently is for many users.
  #19  
Old 03-06-2010, 16:16
Black_glowsticks Black_glowsticks is offline
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benadryl (Diphenhydramine) + hydrocodone

So Swim is sitting in the bathroom looking for a trip, but at least 4 hours ago probably 5 swim took a normal dose of hydrocodone that was crushed and drank. Would it have any adverse affects on swim if swim took 250mg of diphenhydramine? Also swim was wondering if 250mg is to much or to little for first recreational use.


Also sorry swim is a newbie and this is swim's first post, swim has been lurking without an account for ages.

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Welcome to the forum.Good use of 'SWIM' & refers to active ingredient-important on an International forum. +1
  #20  
Old 05-06-2010, 06:30
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Re: benadryl + hydrocodone

Diphenhydramine mixed with depressants doesn't have the risks associated with stronger hypnotics, at least not that I know of. Alcohol consumption before taking diphenhydramine is reported to increase its potency, but it's probably not dangerous otherwise.
Honestly, you'll probably just fall asleep.
  #21  
Old 05-06-2010, 06:37
mokoceno mokoceno is offline
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Re: benadryl + hydrocodone

Diphenhydramine is not fun at all man, storm is right you'll probably fall asleep or just end up feeling like shit if you don't pass out. Swim is pretty sure it's a deliriant if you take it recreationally which pretty much just gives you the same feeling of being sick with the flu or something plus weird quazi-hallucinations if you take enough. Heres a quote from a kid I know who took a bunch. "Every time my heart beats it feels like my head is exploding" and he was yakking and moaning pretty much until he passed out.
  #22  
Old 05-06-2010, 10:48
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Re: benadryl + hydrocodone

Hi, glowsticks. Welcome to the forums.

1st off..... Has SWIY done a significant amount of research on the recreational use of Diphenhydramine? As Moko has said... it is generally a very unpleasant experience. If SWIY has read up on it and weighed out the pros and cons and is still set on trying it, SWIPA would say that yes, 250 mg's would be a good low dosage for a first time and yet would still produce some effects sought after in recreational use. SWIPA would suggest that SWIY has a sober person with them. The hallucinations one may experience during the trip can appear VERY real and cause one to act out in accordance with those hallucinations.

If SWIY has NOT done much research on DPH's recreational potential I would HIGHLY recommend reading some experience reports from others. There is also plenty of info on it here at DF. Typing Diphenhydramine in the search box will bring up a lot of threads.

Now... as far as your main question... SWIPA is not aware of any interactions between Diphenhydramine and Hydrocodone other than increased sedation. That certainly does not mean that there are none... especially when we are talking about non-therapeutic doses. SWIPA is just telling you what he has read and experienced.

Another thing SWIY may want to consider is that a Hydrocodone high is very pleasurable and euphoric (as I'm sure SWIY knows) and with high doses of DPH being unpleasurable and dysphoric, it seems like to do both at once would ruin the pleasure of the opiate high.

Whatever SWIY decides please be smart and do it safely. I hope this helps. Look forward to hearing back from you.

~PA~

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very helpful and informative, thank you =)
  #23  
Old 05-06-2010, 15:13
Black_glowsticks Black_glowsticks is offline
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Re: benadryl + hydrocodone

Swim thanks you all for your replys, and Swim went ahead and took the 250mg of diphenhydramine. Swim doesn't think the codone had any adverse effects, of course Swim can't really say for sure as swim fell asleep about half an hour after taking the pills, though they where interesting dreams.

Black_glowsticks added 2 Minutes and 13 Seconds later...

Sorry about the 2nd post, Swim just remembered that after taking the diphenhydramine he has been feeling sick for the past few days (diarrhea, upset stomach) so Swim doesn't plan on doing it again. Swim thinks swim should just stick to dxm. =P

Last edited by Black_glowsticks; 05-06-2010 at 15:13. Reason: Automerged Doublepost
  #24  
Old 05-06-2010, 19:56
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Re: benadryl + hydrocodone

Quote:
Originally Posted by Black_glowsticks View Post
Sorry about the 2nd post, Swim just remembered that after taking the diphenhydramine he has been feeling sick for the past few days (diarrhea, upset stomach) so Swim doesn't plan on doing it again. Swim thinks swim should just stick to dxm. =P
DXM, when used in moderation, can be a very beautiful drug. SWIPA really enjoys 1st and 2nd plateau doses. He usually will use about 450 mg's and feels thats all he needs. He also noticed that when in this state any cravings for other drugs and/or alcohol are almost completely nullified. He feels at completely at peace with just the DXM, whereas the majority of other drugs make him fiend for more. This is the opposite with DXM.

I will forewarn you however, SWIPA had an experience recently where his stomach got really messed up for 2 or 3 days due to combining opiods with DXM. He didn't even really do them at the same time, he just had gone through a good amount of oxycodone and hydrocodone within a 2 day span and when he ran out, that is when he did the DXM.

Upon taking the DXM (450 mgs) that night, the high was different. He noticed much less euphoria than usual and felt an overpowering need to lay down. His stomach then became VERY upset and he vomited several times that night. He couldn't help but think that this was possibly due to all the acetaminophen in the opiods he had consumed over the course of those few days, and then adding the DXM to it later just did not sit right with his stomach and liver. But he spent the next 72 hours with random stomach pains (though he did not vomit again) and horrible diarrhea. SWIPA has vomited many times from DXM alone, and usually gets diarrhea from it for a short period of time (usually lasting about 6-8 hours tops) but nothing like this so he can't help but think there may have been a connection, so just be careful because there is a possibility SWIY could experience the same symptoms by combining DXM with Hydro as he did with the DPH and Hydro.

Be safe
~PA~
  #25  
Old 16-06-2010, 17:36
MrMunchies MrMunchies is offline
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Dimenhydrinate and hydrocodone: Safe?

If swim were to take 1200 mg of dimenhydrinate, with 25 mg of hydrocodone, could swim die?


swim has safely taken 1100 mg of dimenhydrinate and safely has taken 35 mg of hydrocodone , never has mixed them though?

MrMunchies added 1 Minutes and 0 Seconds later...

I have also forgot to mention that I am around 240-250 pounds.

Last edited by MrMunchies; 16-06-2010 at 17:36. Reason: Automerged Doublepost

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