Drug info - Alprazolam (Xanax) Powder

[namidua]

same question here, I've heard that you can't snort it, buy I beg to
differ. Maybe it was soething else? anyway. What can
be done wiht PURE Xanax powder (not rushed pills)
Edited by: namidua

[namidua]

[raven3davis]

It can definitely be snorted, but be very careful with the dose. Not sure about IM or IV because swim has heard benzos arent very water soluable.

[Jatelka]

Originally Posted by namidua

same question here, I've heard that you can't snort it, buy I beg to differ. Maybe it was soething else? anyway. What can be done wiht PURE Xanax powder (not rushed pills)

Xanax is soluble in ethanol but not water at physiological ph. Hope this helps: (edited by me for clarity)

Snorting xanax reduces its bioavailability by up to 66% and no less than 33%. Obviously this depends on a number of factors such as mucusal membrane functionality, tolerance to triazolo Benzodiazepines with a heterocycline group unique to Xanax or alprazolam. My suggestion is that if you are this desparate for BDZr 1-6 (that we know of) activation for specific GABA instructions for CNS inhibitory mechanisms than chew the pill and keep it under your tongue for five minutes, then just swallow what is left. It should take a mere 15 minutes to feel some effects. THE PROBLEM WITH SNORTING XANAX IS THAT IT IS NOT READILY H2O SOLUBLE.


Additionally drugs which are poorly water soluble do not cross the blood brain barrier effectively (or at all) which means you require higher doses (and thus more chance of adverse effects such as respiratory depression) to achieve your desired effect.


Water soluble benzos include midazolam ,flurazepam and flunitrazepam.

[sg43]

SWIM stumbled upon some pure xanax (alprazolam ) powder, he has a milligram scale so dosing will not be a problem but he still wants to find a better way to dose other then that and liquid dosing, SWIM was wondering if anyone was familiar with some method of cutting this powder with some kid of filler so he could pack capsules or press pills if he wanted to, hopefully somebody can help SWIM out with this concept.

[Benzeneringz]

Why don't you want to use the liquid dosing method? I guess just use flour.

[jesusfreak666er]

swim thinks cutting is a poss. but one must make sure they do a sufficent job in mixing, It would be a pain to be off in measurements. Sift the powders together a few times and take it slow, but liquid dosing sounds much more efficient.

[fatal]

if you do it wrong and you have a "hotspot" in your powder it could kill someone pretty easily. keep that in mind.

[sg43]

So far SWIM got these ideas from another forum:

"The alprazolam capsules I've already prepared were made dissolving it in alcohol, filling the capsules and evaporating. The capsules look a little bit funny after the process and I only had 96º denaturalized alcohol. I don't really like ingesting bitrex even if its in such tiny quantities. I was discussing where to buy pure alcohol here (its illegal to sell it without denaturalizing it) and some chemist friends suggested a method to mix it with inert powder in a secure way. Will explain it when I have tried it.

Basically consists on putting it on a container and mixing it (turning the container around) for some hours with a material with a similar density. Then adding more mixing agent and letting it mix more time. After that filling the caps. It's what usually is done in labs but at home in a more ghetto way."

SWIM is wondering how he would go about finding something with a similar densitiy to do this with, if anyone can elaborate SWIM would be extremely grateful.

[sourceman]

Originally Posted by sg43

So far SWIM got these ideas from another forum:

"The alprazolam capsules I've already prepared were made dissolving it in alcohol, filling the capsules and evaporating. The capsules look a little bit funny after the process and I only had 96º denaturalized alcohol. I don't really like ingesting bitrex even if its in such tiny quantities. I was discussing where to buy pure alcohol here (its illegal to sell it without denaturalizing it) and some chemist friends suggested a method to mix it with inert powder in a secure way. Will explain it when I have tried it.

Basically consists on putting it on a container and mixing it (turning the container around) for some hours with a material with a similar density. Then adding more mixing agent and letting it mix more time. After that filling the caps. It's what usually is done in labs but at home in a more ghetto way."

SWIM is wondering how he would go about finding something with a similar densitiy to do this with, if anyone can elaborate SWIM would be extremely grateful.

I will do my best to explain this process, but I am interested in hearing what you chemist friend told you about mixing it..

To start off with, find a filler/binder that has roughly the same molecular weight (MW). Swim thinks Alprazolam is around 310 (just chexked and it is 308.8 lol.. not a bad guess!!) SWIM remembers from doing trandermal experiments with this powder.. Now once SWIY finds the binder/filler the next step is to figure out the mass off he needed filler for the capsules to be filled or pill to be pressed. SWIM assumes SWIY knows how to do this. If not , ask.

OK. Let's say that each capsule will hold 500mg filler. 100 Caps is what SWIY wan't to make, then 50g filler is needed. powder the filler finely with mortar and pestal. place in sealable container.

if the desired dose is 2mg/cap, then 200mg is needed. This is best done by throug liquid measurement, SWIM believes. 99.7 % pure alcohol can hold40mg/ml alprazolam. So 5ml is needed for this process. Draw up 5ml solution.

This is where people have different views. one method is to add the solution to the filler, draw another ml or 2 of CLEAN alcohol and flush syringe. mix container wekk, and let evaporate. Then grind in the mortar and pestal again making sure to mix very thoroughly.

Another method is to let it evaporate in the bast of the mortat and pestal and then add the filler and mix vigorously.

SWIM likes the first method.

Next fill the caps!

If a large batch is desired, aquire a parts tumbler (that is used to sand, grind, polish etc different objects. it is a drum that lays on it's side and rolls over and over. if sand is in ther and you put rusty metal, it will remove the rust and polish the metal). These can be purchased very cheaply for $20-50. Add the filler/binder, add the alcohol mix, throw in some LARGE Stainless Steel ball bearings and let it run for at least 12 hours. The longer the better! this generates heat by the tumbling, so it evaporates the alcohol fairly fast.

Also, if SWIY needs to know how to get alcohol to 99% LMK!

Reputation Comments on this post:

awesome post. very well explination of dosing alp powder. might even have to pm him for more info. A+

[raven3davis]

Just dillute the alp powder into the grain alcohol. 20mg/ml should seem about right. So each 1/10ml should contain 2mg. Get a syringe and draw up 10units, which is the same as 1/10ml. Those ten units should be holding 2mg. just shoot that in your mouth and have a good time. Chase with a beer if necessary. Hide well so no one will mistakingly take a shot or something.

[jesusfreak666er]

denatured alcohol is horrible idea, its not drinkable, and leaves residue once evaporated swim believes, they add stuff to the alc so they can sell it tax free. swim doesn't know if the amount ur using is dangerous but still not a good idea.

[sourceman]

^^ Raven, you are right about the grain alcohol. It will hold 20mg/ml in solution very easily. Grain is 190 proof, which means that it is 5% water. you wouldn't believe how much to 5% effects the alcohol in getting the alprazolam into solution. If water is removed by desiccation, you can reach 40mg/ml. Either way, it works well. If a large batch is being made or it is being injected in capsules, the minimum amount of liquid is desired.

^JF666r - After looking over the posts, there seems to be no mention of denatured alcohol. That is correct though, one could die or go blind if one injested that substance. The poisenous substance is called Methanol (aka, methyl alcholol or wood alcohol). it is added to Ethanol (drinkable type) to denature it, making it undrinkable.

[raven3davis]

So if you had inactive powder in a capsule, could you squirt the 10 units (.1ml) into the capsule holding the powder so the powder would absorb the liquid and it would be laced with your alprazolam. Would this work, or would the capsule break open? These are all good ideas, but mixing the powder first with a filler seems like the most time consuming and complicated method.

You might as well just get a really good scale and individually dose each cap.

[sourceman]

Originally Posted by raven3davis

So if you had inactive powder in a capsule, could you squirt the 10 units (.1ml) into the capsule holding the powder so the powder would absorb the liquid and it would be laced with your alprazolam. Would this work, or would the capsule break open? These are all good ideas, but mixing the powder first with a filler seems like the most time consuming and complicated method.

You might as well just get a really good scale and individually dose each cap.

Adding .1ml to cap wil work fine. Also, if one is prescibed a med in capsule form, one could inject the .1ml into the capsule and swallow! SWIM know many people who injest liquid's this way. Also, yes, the powder would be laced. The capsule shouldn't break open.

Also, mixing powder first with filler is more time consuming but yeilds a better end product SWIM believes. If making many for personal consumptin it is much faster this way than injecting 100's of caps, and easier on the hands!

[sg43]

SWIM decided to continue on this project, only one problem, in his state pure 200 proof alcohol is nowhere to be found, he knows that he could use methanol but wants to do the liquid dosing and fill empty capsules with the solution and methanol is toxic so that would not be safe for consumption and anything under 200 proof will cause the capsule to break down and turn into a gel like goo.

Any suggestions would be greatly appreciated.

[Forthesevenlakes]

200 proof, to swim's understanding, converts to about 190 proof after exposure to air, due to absorption of water from the environment. if pure ethanol would be acceptable to put in empty capsules, then everclear should also work, since that is 190 proof.

[Psych0naut]

Originally Posted by fatal

if you do it wrong and you have a "hotspot" in your powder it could kill someone pretty easily. keep that in mind.

It won't kill someone "pretty easily".Though it can knock someone out, benzodiazepines are very safe when overdosed, except when thery're taken with other CNS depressants.

[Forthesevenlakes]

other CNS depressants including alcohol. hm, maybe alcohol isnt the best thing to be dissolving the benzos in, then...although if swiy is only ingesting a minute amount it may not be too harmful.

[Sklander]

1/10ml of alcohol = 2MG = One Xanax (Bar)

That amount of alcohol will have no effect whatsoever. In fact, the alcohol will probably evaporate leaving only Alprazolam powder.

SWIM just picked up a few Marshmellows that have been injected with 2MG Alprazolam each. A very creative friend of SWIM's came up with this! GummyBears have also been used with success. Marshmellows seem to absorb best, though.

[Forthesevenlakes]

Originally Posted by Sklander

SWIM just picked up a few Marshmellows that have been injected with 2MG Alprazolam each.

That would make one hell of a cup of hot chocolate. Swim hopes this idea doesnt spread though, swiy may be using them responsibly but the last thing the forum needs is people asking questions on how to shoot up junk food =]

[Ranke]

SWIM recently came into a fortune in alprazolam powder. Unfortunatly he doesn't have a .5mg scale. So he wants to try dissolving a known amount in a liquid and dosing that way. SWIMS question is this. Would leaving 1g of alprazolam in a liquid over a long period of time degrade it? The liquid SWIM is considering is mouth wash (swim is under 21 and cannot buy alcohol)

[rxbandit]

swim notes that swim has left aprazolam powder for 2 weeks with out any notable change in kool-aide drink. swim would recomend getting a somewhat precise scale or weighing as close to 100 mg's on a normal scale and then dilluting it heavily so any small inaccuracys wont become tragic. 4 mg's of this powder knocked swim out for 18 hours within 30 minutes or so.

swim has used water, shaking before consumption with multiple succesful dosings without much difficulty...

[Ranke]

so alprazolam is somewhat soluble in water? If so swim will just use that. What he wants to do is dissolve the powder into some solvent then put drop with 2mg onto pieces of cotton, paper, cloth, or any other absorbant material and place that into pills when dry. Does this seem feasable?

[Forthesevenlakes]

SWIM had just typed out a response to this, and then accidentally shut the firefox window, so here goes again...

Alprazolam at 37°C was 0.045 mg/mL soluble in water. This is to say, not very soluble at all. So dissolving in water would not work that well. It would be more soluble in alcohol but there would be the risk of evaporation, so it would not work as a long term storage solution if put onto cotton really. Unless SWIY wants the alcohol to evaporate and then puts the cotton into pills, but the cotton would already have to be precut into small sections, SWIM thinks. Maybe it'd be soluble in DMSO or PEG if swiy has access to those?

But really as stated before the only TRULY safe way to measure this out is with a good scale...xanax is active even at low doses so it would pay to be safe, even 2 mg is enough to knock some people out!