Complete List of Opioid Dosages

[MrJim]

Ok guys,


SWIM needs everyones help here. There are many great minds in here soSWIM can't wait for input. He gathered the following information from a variety of places and he needs verification and expansion. Think a dosage is Way off? How about another drug left off? How about ANY pertinant information for this list. A wise one said that compiling a list of opioid dosages is something that comes with great responsibility.


So - This is it - For educational use only
Opiates are a difficult substance to provide standard dose information about. People all have different natural tolerances to opioids, which can increase dramatically over the course of their personal usage. I have personally known people who went from a 100mg of heroin in a day to trying to catch a similar buzz off of 500mg a day within 4 or 5 months. I have heard of some people using up to 2.5 grams in a day of Heroin after long term addictions.

OPIUM (refined) - Oral dosages - 1/3 -1/2 gram. Note that opium dosages can vary because every opium has different quantities of active alkaloids in it. Oral is a more risky way to injest because you can't control the dosage as well as with smoking. 2 grams can easily be fatal. (Bogumil - from Opium basics).
-Smoking - A matchhead sized piece at a time. 0.1 gram. You can feel opium almost instantly when smoked so it is easier to find a safe dosage this way.

Morphine - For the non-opiate tolerant 10mg, orally should be enough to produce euphoria. Morphine is more bioavailable insufflated and rectally, and for these routes, 5 mg would be enough to start with. Morphine is the bar to which other opiates are measured in terms of relative strength For more info see Fantasian's post - http://www.drugs-forum.com/forum/sho...504#post159504

Codeine - For the non-opiate tolerated a 75-125mg dose should be good to start safely with this drug Insufflation is not advised since this drug usually comes with acetaminophen for most preparations. For more info see Fantasian's post - http://www.drugs-forum.com/forum/sho...504#post159504

Thebaine – Not really a recreational drug in this form –a stimulant which can cause nausea but does act on the opiod receptors (much less at mu receptors than morphine-like substances.

Heroin (diamorphine) - Rarely seen in pure form since it basically lives as a street drug –Pure heroin dosage for the non-opiate tolerated –5-10mg injected 5-20mg snorted or smoked.

Oxycodone - for the non-opiate tolerated a 10-15mg oral dose should be sufficient. Insufflated or rectal would be 5-10 mg.

Hydrocodone, - for the non-opiate tolerant 10-20mg first dose. Insufflation is not advised since this drug usually comes with acetaminophen for most preparations.

Dihydrocodiene - 60mg would be a safe starting dose for the non-tolerated. Insufflation is not advised since this drug usually comes with acetaminophen for most preparations.

Hydromorphone, for the non-tolerated 2mg orally would be a safe start. 1-2 mg insufflated.

Oxymorphone, 1 – 1.5 mg injection, 2 mg orally for a start dose.

Buprenorphine, - Mixed agonist-antagonist effects. For treatment of opioid addiction. Starting dosage is reflective of level of opioid addiction prior to treatment. "0.5-1mg sublingual or via nasal route are a safe starting point for a non-tolerant novice user. Subutex comes in 2 and 8mg tabs. Sensual effects only develop after about 20-30mins and last 24-48 hours" - Credit - Citizen Kane. For more info see Fantasian's post - http://www.drugs-forum.com/forum/sho...504#post159504

Etorphine, - Not for Human consumption – Too dangerous to measure microgram readings. A scale affected by as little as an air current in the room could cause a measurement dosage large enough to kill someone. 1mg given to a five-year old African elephant knocks it out.

Naloxone - A Opioid antagonist – not for use unless someone has overdosed. Do not play around with this unless you want to feel violently ill.

Nicomorphine – more or less equivalent dosages to morphine. 10-30 mg injected is used in the drug clinical trials with significant analgesic effect.

Methadone – Typically used for maintenance programs to wean people off of opiates therefore the starting dosage is reflective of the level of opioid addiction that the patient suffers. It comes in 5, 10 and 40mg tablets as well as an injectable suspension.

Meperidine (Demerol), 50 mg would be a safe dose for the non-opiate tolerated first dose in tablet form. Injections would be about 25mg.

Fentanyl - Normally packaged as a 3-day patch. For injections 0.05mg would be a safe start. 0.1mg smoked. 50-100 times more potent than morphine. For buccal ingestion via Actiq lollipops 100-200 mcg would work for someone with no tolerance.

Alfentanil – 200-500 micrograms is a typical injection. Short acting and potent it is a drug very similar to fentanyl.

Sufentanil – 50 microgram injections are used to treat pain. All of these Fentanyl sub-type drugs are extremely easy to overdose on and utmost caution should be used around them.

Remifentanil – Another of the Fentanyl group. It differs in that it is the first ultrashort acting potent opioid for strong pain relief in a short period of time. Dosage is 0.5-1.0 ug/kg.

Carfentanyl -Another one not for Human consumption. It has a relative potency of up to 10000 times that of Morphine. Used to sedate large animals.

Ketobemidone - Dosed similar to Morphine. Normally only available in Scandanavia (credit - Hitme2ice)

Propoxyphene - (Darvocet) - 120-160mg for the novice user. Insufflation is not advised since this drug usually comes with acetaminophen for most preparations.

Pentazocine – (Talwin) Often mixed with a opiate antagonist to prevent abuse. 50-100mg orally or 30mg IV is a typical dosage.

Phenazocine – This one has been discontinued in many countries. 3mg was a typical dose to cause the analgesic effects of about 20mg of Morphine.

Tramadol (Ultram)– 200mg sustained release tablets are a safe starting point. Due to the size of the pills and the binders in them, snorting is not advised, nor does it seem well-absorbed through this route. Very little recreational effects (disputable) but effective pain killer. For more info see Fantasian's post - http://www.drugs-forum.com/forum/sho...504#post159504

Loperamide – No recreational value – does not cross the blood-brain barrier. Acts on the opioid receptors of the gastrointestinal tract. 2mg relieves diarrhea.

Always take less of a drug if one is naïve to it. It is better to learn what is not strong enough for you than what is too strong.

Reputation Comments on this post:

	Very good post! Excellent compelation of the recommended doses of many opiods. He has been responding to peoples posts ...
	Great post on various opiates
	great info
	Excellent post. :)
	Good work!
	very helpful, thanks
	I can't believe I didn't give you karma for this already!
	this thread is amazingly awesome and should have a link in the header, though you need to edit your header a bit to fix ...
	Great list, this should come in handy for many SWIMmers
	Extremely helpful. Thanks.
	Nice work.
	Good info on opiate dose
	Good!
	great work, interesting and useful list
	great idea, good info
	Possibly the most informitive post I've ever seen
	great thread, very useful information
	Great post, SWIM is astounded that such a small amount of etorphine could knock out an elephant :O
	exellent info
	Good stuff bro, this'll be helpful to alot of us
	informative post, with clear dosage ranges. keep it up!
	A valuable compilation of dosage info. Quite good as a quick reference for opiates dosages.