as far as dopamine
uptake is concerned, methamphetamine
is about 1.2-1.5x as potent, but methamphetamine is also strongly serotonergic so it takes a higher dose to feel as "tweaked"
methamphetamine is a "softer feeling" drug
(mg for mg) because of the serotonergic action's softening/smoothing/balancing of the dopamine and norepinephrine release.
a lot of people w/ADHD who get prescribed desoxyn after adderall
or dexedrine are underwhelmed, find it rather "weak" in its motivational and focus enhancing effects. the serotonergic action of the drug regulates the dopaminergic action, but when you get into higher recreational dosages you get a large release of both which is very euphoric. desoxyn is great because it is relatively free of the obnoxious side effects
of standard stimulants
like insomnia, mood swings, irritability, dehydration, which makes it a good option for daily use and doesn't "force" focus, but allows the user to have better control over his natural focusing mechanisms, but if you want to pull an all nighter, you're better off with plain old dexamphetamine because of the more "unregulated" dopamine/norepinephrine release..
this may seem like hocum, but i assure you it isn't, just consider most who take dexies or adderall are taking maybe 10-30mg at a time to get pretty ramped up (with newb tolerance) while that figure is probably much higher for methamphetamine depending on the purity of the sample, and why weak or shit methamphetamine is rather underwhelming as well, and may be better suited as a "mood enhancer" than a recreational drug.