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  #1  
Old 22-03-2010, 05:26
shroomngreen89 shroomngreen89 is offline
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Can you inject Tramadol??

Is injecting Tramadol undesirable. SWIM knows that tramadol is readily soluble in water but dosen't know if the effects are diffrent than orally.
  #2  
Old 22-03-2010, 05:52
OpiLuvnOldLady OpiLuvnOldLady is offline
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Re: Can you inject Tramadol??

Swim's searching here turned up these two results. It seems that this would depend on whether one is talking about capsules, or IV/IM solution. The prepared solution seems to be a viable option, but the capsules are not easily converted to an injectable form and is highly discouraged.

By using the search engine, she found these:

http://www.drugs-forum.com/forum/sho...03&postcount=4

http://www.drugs-forum.com/forum/sho...nject+tramadol

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Helpful re-directs point out value of UTFSE & existing info. on DF.Thanks
  #3  
Old 22-03-2010, 06:00
shroomngreen89 shroomngreen89 is offline
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Re: Can you inject Tramadol??

Well there not capsules but tablets, I guess it'll be trial and error for SWIM
  #4  
Old 22-03-2010, 06:06
OpiLuvnOldLady OpiLuvnOldLady is offline
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Re: Can you inject Tramadol??

Swim would like to ask if swiy is already experienced with converting tablets. If not, then she would suggest at bare minimum reading the pill prep thread first.

To be honest, she doesn't have a good answer on whether the tablets can be converted, but if swiy is insistent on trying, please at least take caution to try and remove as much filler/binder as possible.
  #5  
Old 22-03-2010, 06:17
shroomngreen89 shroomngreen89 is offline
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Re: Can you inject Tramadol??

Swim has been injecting opiates for sometime and always use a micron filter.
But Swim has never injected Tramadol before.
  #6  
Old 22-03-2010, 07:11
OpiLuvnOldLady OpiLuvnOldLady is offline
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Re: Can you inject Tramadol??

Swim is glad to hear that this is not an attempt with out any experience behind it. Even though she's still not sure about the tramadol, she's at least glad to know that swiy is not new to this and it not gonna drop a pill into a rig and then think they can shake and shoot. lol
  #7  
Old 22-03-2010, 07:47
Picass035 Picass035 is offline
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Re: Can you inject Tramadol??

SWIM has IV'ed USP Tramadol ampoules before..it doesn't get any purer than that.

TRIP REPORT

Foreword: slight opiate tolerance, but minimal at time of this report.
T-00: Find vein, inject 50mg.
T+1 min: "Strange, usually I'd be feeling SOMETHING by now," SWIM says
t+5 mins: decides to IV another 50mg. Maybe a single does wasn't enough?
T+7 mins: find another vein, inject another 50mg (so 100mg total IV'ed <10mins)
T+8mins: there's something that "seems" to be happening..no that was my imagination..
T+9 mins: "There it it is again, that "coming up" feeling!" No, nothing again.
T+10 mins: HEADACHE!!! UGH!!! NASTY S%!#!!!!
T+/- 2 hours: headache subsides, feeling better.
-----

Now some people like Tramadol, some absolutely LOVE the stuff. Not SWIM. He will never touch this evil substance again (and he has tried taking the tablets/capsules orally just to make sure it wasn't a fluke). No go. Headache each time. On the other hand, SWIM's cousin can be pain-free from 50mg orally. She has no tolerance but still. It's just how we're wired I suppose.
  #8  
Old 25-03-2010, 03:13
fiveleggedrat fiveleggedrat is offline
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Re: Can you inject Tramadol??

Orally is significantly better.

Personal experience by Swim.

Tramadol cannot metabolize the same efficacy when IV, equals loss of M1, most potent mu agonist product of tramadol. m1 is stronger than tramadol alone.

Tramadol is best dosed 50mg every 5-10minutes for most m1 buildup. The process increases with efficiency when done this way.

IV = less opioid, more SSRI/SNRI

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Interesting information!
  #9  
Old 01-04-2010, 03:16
Picass035 Picass035 is offline
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Re: Can you inject Tramadol??

I did not know that, although when you think about it, it really does make sense. Orally, it has to go through first pass metabolism, converting part of the tramadol into O-desmethyl-tramadol (M1). With IV, since you skip first pass metabolism, no M1 can be made.

Hopefully I got it right. Not too familiar with Tramadol since it is one of the WORST drugs SWIM has ever done. Ugh.

If I'm wrong about how first pass metabolism works with tramadol, could someone correct me?

Quote:
Originally Posted by fiveleggedrat View Post
Orally is significantly better.

Personal experience by Swim.

Tramadol cannot metabolize the same efficacy when IV, equals loss of M1, most potent mu agonist product of tramadol. m1 is stronger than tramadol alone.

Tramadol is best dosed 50mg every 5-10minutes for most m1 buildup. The process increases with efficiency when done this way.

IV = less opioid, more SSRI/SNRI

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injecting, injecting pills, intravenous injection, tramadol, tramadol abuse

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