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  #1  
Old 13-03-2010, 01:38
psychedelaholic psychedelaholic is offline
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Best completely OTC opiate potentiation 'recipes'

Whilst there are plenty of threads on opiate potentiation SWIM thinks it would be a good idea for other SWIMmers to post ther most effective specific combinations of various potentiators with opiates that are all available over the counter. With amounts of each and times to take them.

These are the best combinations SWIM has found so far (these are OTC in the UK):

CWE codeine:
256mg codeine CWE plugged
Quinine (500ml Tonic water)
40mg Promethazine
6mg loperamide

One box of 8/500mg codomals giving 32x8mg codeine - 256mg with up to around 10% lost during extraction however plugging the CWE adds around 10% due to increased bioavailability. SWIM drinks a pint of tonic water an hour before, the quinine increases the amount of codeine converted to morphine. 40mg of promethazine taken just before taking the CWE rectally. Can't remember how the promethazine helps but I think it's something to do with the way the codeine is metabolised. SWIM also takes 6mg of loperamide with the promethazine which increases the opiate buzz.

This combination produces a really good codeine buzz, the promethazine makes it a lot stronger and the loperamide definitely has an effect too. Not sure how much the quinine helps though, SWIM has not done a comparison of the same combination without it.

EDIT: Having read up about plugging codeine it looks like its not worth the effort. It has such a high oral bioavailability that even if it has a slightly higher rectal bioavailability it isn't going to be much and taking a few ant acids will be just as effective.

Morphine linctus:
20mg morphine orally
1 litre of grapefruit juice
150mg Ranitidine

SWIM drinks a litre of grapefruit juice an hour before the morphine and takes 2 75mg ranitidines half an hour later. He then drinks one bottle of J Collis Brownes which contains 20mg of morphine. This is a really low dose but only one bottle can be bought at once and it's hard to find however SWIM has gotten good effects from this dose when potentiated. The effects were fairly mild but lasted for a good 8 hours. Although SWIM hasn't tried combining it with antihistamines which would help increase the strength of the high.


SWIM is yet to attempt potentiating dihydrocodeine which is also available OTC.

Post Quality Evaluations:
useful information for many

Last edited by psychedelaholic; 15-03-2010 at 21:04.
  #2  
Old 13-03-2010, 06:15
OpiLuvnOldLady OpiLuvnOldLady is offline
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Re: Best completely OTC opiate potentiation 'recipes'

Lately swim has been without her usual prescriptions, so they've been coming in bursts from her urgent care doc. Usually she is given 30 to 40 of the 5/325 Percocets (hydrocodone/apap).

The ritual she performs goes something like this:
Arrive at house and start CWE process, grinding pills etc
Prep filtering equipment and wait impatiently for powder to fully disolve
Eat 5-7 large soup spoons of frozen grapefruit juice while staring at bottle in freezer and cursing to herself
Start filtering
Get frustrated waiting on filter, check clock to make sure it's been at least 40 mins since frozen juice
Pour more into filter and go get tums
Come back to kitchen, pour more in filter and take tums
Watch impatiently as filtering finishes
Swallow some of the goodies and then go enjoy

After having read the entire other thread here about potentiation, and experimenting on her own, she has found the frozen grapefruit juice to be convient because of it's concentrated state not giving large volumes in her stomach, and having learned that the substance that helps to inhibit the liver is most concentrated in the fruit rind. Frozen juice is processed with whole fruit, not peeled. Then the tums are there for the neutralizing of the ph in the stomach for better absorption.
  #3  
Old 13-03-2010, 07:02
Bunnintreez Bunnintreez is offline
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Re: Best completely OTC opiate potentiation 'recipes'

SWIM hasnt potentiated any OTC opiates because swim does not kno which ones contain codeine. but this is the ritual swim has when he only has a small amount of Oxycontin or Perc's.

Swim consumes 1-1.5 litres of grapefruit juice
takes 50-100mg of Benedryl
2 tums
waits 45 minutes to an hour
parachutes(crush up very small and put in a thin layer of toliet paper and swallow) 10-30mg(or w.e little amount there is) of oxycontin or the CWE 5mg percs.
  #4  
Old 13-03-2010, 07:32
malsat Gold member malsat is offline
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Re: Best completely OTC opiate potentiation 'recipes'

Quote:
Originally Posted by psychedelaholic View Post
Whilst there are plenty of threads on opiate potentiation SWIM thinks it would be a good idea for other SWIMmers to post ther most effective specific combinations of various potentiators with opiates that are all available over the counter. With amounts of each and times to take them.

These are the best combinations SWIM has found so far (these are OTC in the UK):

CWE codeine:
256mg codeine CWE plugged
Quinine (500ml Tonic water)
40mg Promethazine
6mg loperamide

One box of 8/500mg codomals giving 32x8mg codeine - 256mg with up to around 10% lost during extraction however plugging the CWE adds around 10% due to increased bioavailability. SWIM drinks a pint of tonic water an hour before, the quinine increases the amount of codeine converted to morphine.
1. Quinine is a 2D6 inhibitor. An active dose of quinine will make codeine less potent. IDK where this misinformation about quinine being an effective potentiator for codeine came from, this is the second thread I've seen in the past couple days with this erroneous claim.

2. The amount of quinine in modern tonic water is clinically insignificant - studies have found that even drinking 1000ml of tonic water has no significant effect on 2d6.

http://www.sciencedirect.com/science...fa3cf6731711bc

So, you are completely wasting your money by using tonic water.

Post Quality Evaluations:
Good solid information and contribution, even if it was worded a tad harshly.
well done, would have given more points but for the harsh tone

Last edited by malsat; 13-03-2010 at 15:07. Reason: spelling
  #5  
Old 13-03-2010, 11:56
psychedelaholic psychedelaholic is offline
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Re: Best completely OTC opiate potentiation 'recipes'

Ah thanks for the information SWIM got that belief from this article: http://opioids.com/opiates/index.html

Quote:
2. Quinine and quinidine accentuate the buzz of opiates but only directly help with codeine metabolism by boosting the amount changed into morphine. The prescription antihistamine promethazine (Phenergan) helps out codeine even more, and is found with codeine in the Schedule V cough syrup Phenergan VC With Codeine. Quinine will tend to have its effect without impairing hydrocodone but does seem to burn off the buzz more quickly and may flatten the dose-to-response curve.
  #6  
Old 13-03-2010, 12:37
blink1989 blink1989 is offline
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Re: Best completely OTC opiate potentiation 'recipes'

Quinine would work to Potentiate Dihydrocodeine (not a pro-drug), SWIM believes.

To the OP, would it be feasable to consider plugging the J.Collis Brownes? Swim knows that the stuff has 20mg of Morphine /100ml. So if one were to plug say half the bottle and dring the other half... SWIm would imagine it would feel like ~30mg Morphine. although plugging that much syrup does'nt sound appealing
  #7  
Old 13-03-2010, 15:16
malsat Gold member malsat is offline
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Re: Best completely OTC opiate potentiation 'recipes'

Hey I'm sorry if I came across as harsh there, I really didn't mean to be.
  #8  
Old 15-03-2010, 11:14
psychedelaholic psychedelaholic is offline
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Re: Best completely OTC opiate potentiation 'recipes'

Quote:
Originally Posted by blink1989 View Post
Quinine would work to Potentiate Dihydrocodeine (not a pro-drug), SWIM believes.

To the OP, would it be feasable to consider plugging the J.Collis Brownes? Swim knows that the stuff has 20mg of Morphine /100ml. So if one were to plug say half the bottle and dring the other half... SWIm would imagine it would feel like ~30mg Morphine. although plugging that much syrup does'nt sound appealing
I don't think the amount of syrup would be too bad to plug, when SWIM plugged the codeine CWE that was 100ml of solution and he had no problem with that. No sure if the other ingredients would be bad to plug though:

Quote:
Each 5 ml dose contains Morphine Hydrochloride equivalent to 1 mg Morphine Anhydrous and 1.5 microlitre Peppermint Oil Ph. Eur
Also contains Ethanol (96%), Benzoic Acid (E210), Caramel (E150), Citric Acid (E330), Sorbitol Solution
Ethanol: 2.13%v/v per 100ml bottle, see Patient Information Leaflet
Don't know if the benzoic and citric acid would cause irritation or the peppermint and sorbitol might cause problems. No idea though. Plugging the 20mg of mrophine would definitely be better than taking it orally.
  #9  
Old 19-03-2010, 19:48
vellocet vellocet is offline
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Re: Best completely OTC opiate potentiation 'recipes'

Plugging the ethanol is a definite no-no, it will severely irritated Swiy's intestines. The ethanol could probably just be cooked out of the syrup over an electric stove at a low heat. Perhaps there's a way to concentrate the syrup more or extract the goodies.
  #10  
Old 19-03-2010, 21:19
psychedelaholic psychedelaholic is offline
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Re: Best completely OTC opiate potentiation 'recipes'

Quote:
Originally Posted by vellocet View Post
Plugging the ethanol is a definite no-no, it will severely irritated Swiy's intestines. The ethanol could probably just be cooked out of the syrup over an electric stove at a low heat. Perhaps there's a way to concentrate the syrup more or extract the goodies.
Well it only has 2.13ml of ethanol in it so I wouldn't of thought that would be much of a problem since people do things like wine enemas, I would of thought the other ingredients would cause much more irration.
  #11  
Old 20-03-2010, 00:32
BumpBump BumpBump is offline
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Re: Best completely OTC opiate potentiation 'recipes'

swim tried to plug j collis brownes once even waterd down... its not goood. too much alcohol and other stuff to aggitate up there. Your body willl try and expelle it... trust me lol.
  #12  
Old 12-04-2010, 20:17
starfarer starfarer is offline
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Re: Best completely OTC opiate potentiation 'recipes'

Quinine will not potentiate DHC. DHC needs CYP2D6 to convert it to dihydromorphine. Inhibiting cyp2d6 will limit the amount converted thus attenuating analgesia.
  #13  
Old 15-04-2010, 11:03
Pieces Mended Pieces Mended is offline
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Re: Best completely OTC opiate potentiation 'recipes'

SWIM has found a method to make 10mg of hydrocodone, which would normally barely hit him, feel like it is at least 20-25mg. Here is SWIM's method:

-0:30 = take two Tagment pills
-0:10 = chew one 1000mg Tums
+0:00 = 1/2 Darvocet, 1/2 Norco (5mg hydro), chase with 8oz grapefruit
+0:15 = 1/2 Darvocet, 1/2 Norco, 50mg Tramadol
+0:30 = chew one 1000 Tums, chase with 8oz grapefruit

By using this method, SWIM has had some amazingly strong experiences. Darvocet, while almsot useless by itself, seems to have an amazing impact on hydrocodone. However, you need to be careful, since each one has 700mg of APAP- so either limit yourself to one Darv and one Norco, or you need to use CWE to be safe. Also, just the simple 50mg of Tramadol seems to greatly increase the impact for SWIM. It almost seems to have the same synergy that say, 15mg Adderall would have in combo with the Hydro. However, SWIM wouldn't suggest going beyond a single 50mg, as Tramadol is one of those drugs that can be fairly unpredictable when mixed with anything else.

Lastly, SWIM has found that once you've taken the Tagment, Tums, and grapefruit juice before and with the opiates, there is still a benefit to following with one more round of the second two items a little while afterward.

Basically, SWIM hasn't had to go past 15mg of Hydro in a given night to have fun since using this method. Using only the Norco, he'd have to take 20-30mg to have the same effect. Of course, not everyone has access to Darvocet- most doctors consider it useless by now, since it truly is, but luckily SWIM does have some laying around.
  #14  
Old 17-04-2010, 02:10
lostndalone lostndalone is offline
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Re: Best completely OTC opiate potentiation 'recipes'

[QUOTE=OpiLuvnOldLady;789186]Lately swim has been without her usual prescriptions, so they've been coming in bursts from her urgent care doc. Usually she is given 30 to 40 of the 5/325 Percocets (hydrocodone/apap).


swiyopiluvn , swim is unclear if your talking about the drug hydrocodone or if your talking about oxycodone which is one of two active ingredients in percocets. please clarify for swim and other swiys who read this post , if for nothing else it will be accurate info... swim knows it must sound dumb comming from such a newbie such as myself and swim is 110% sure swiyopiluvn knows what drug they are talking about which is why its so silly , but just wanna make sure other swiys who maybe dont know the difference arent given wrong information and run to their friends like " hey look guys , swim just got some sweet hydrocodone percocets!!"

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