kitten has been on both venlafaxine
) and duloxetine
) and has experienced similar issues... the major difference between these two antidepressants
and others is that they have norepinephrine reuptake inhibition properties, although venlafaxine does not exhibit it until one gets to doses of 250 mg and up, where side effects
become a problem for many. duloxetine has ssri
and snri properties at the beginning (20mg) dose, ten times less than that of the former, and thus less likely to induce nasty side effects.
still though, kitten has found that it affects sex drive almost as much as high doses of venlafaxine; she is tapering off of duloxetine, VERY slowly, and is down to about 5 mgs a day, and still lacks much interest, but has had a much less difficult time comin off of duloxetine than she did venlafaxine, which was very difficult to come off of, even with a long, slow taper.
in short: both seem to negatively affect sex drive, and if one wants it back by getting offf of the meds as LONG, SLOW TAPER is essential, especially with venlafaxine, as one can become dysphoric and even suicidal alarmingly fast.
be safe and good luck!