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ok SWIM was prescribed 40mg Vyvanse. He has done alot of research and cannot get a straight answer about recreational use. He wants to know something very simple. Can this stuff get you high? and if so, how much does he have to take.
Yes its amphetamine it can get you high. But remember to use the search engine because theres actually a tutorial to take out the part of the medication that makes it have to be metabolized by the liver. So it just becomes Dextro-amphetamine.
SWIM would just like to update everyone. He took 80mgs total of Vyvanse and at first thought it was shit. He felt a small high from it, kinda dirty, and actually his head was cloudy which he thought was wierd cause its supposed to improve concentration. but then he waited a little bit longer and it turned into a full blown amphetamine buzz. very very nice! SWIM says the high is more body oriented than Adderall but there is still a nice positive mood lift and definately increased empathy. SWIM is pleasantly surprised with this since he was expecting utter bullshit.
SWIM had his first encounter with Vyvanse the other night. SWIM has extensive experience with amphetamines and especially methamphetamines but had never encountered Vyvanse yet though SWIM had heard of it.
SWIM had not taken an upper (coke or amps) for about 8 months but decided to take 40 mg of Vyvanse just to see what it's all about. It took almost an hour and a half for the drug to take effects but it lasted for a good 9-12 hours; SWIM was talking his fucking ass off all night and had a blast. Eventually once everyone else had passed out SWIM threw a 2 mg Xanax bar under his tongue and slept like a baby.
Vyvanse is weird; it is actually a prodrug of amphetamine (lisdexamfetamine) and it takes about an hour for your body to convert the lisdexamfetamine into dextroamphetamine. This is true genius on the part of the manufacturer because it makes recreational abuse (crushing,snorting, shooting, plugging) almost impossible.
Generally the equivalence given is 20 mg Vyvanse = 10 mg Dextroamphetamine XR but if you look at the pharmacokinetics it is much more complicated than that because of the way the amphetamine prodrug is encapsulated.
Based on SWIM's experience, it takes a long time for the amphetamine to get in your system because it must be metabolized first, but it is quite effective. SWIM would say 30 mg Vyvanse = 30 mg Adderall XR. If SWIM could figure out a way to convert to amphetamine, things might be a little more fun though.
In swims experience, it's hard to really "abuse" vyvanse or get a "high" from vyvanse due to the fact that the manufactures specifically made it that way on purpose. Sure it will speed things up in your life- make you accomplish 10 times the tasks as you might otherwise, but there's definitely not the same high that can be achieved by other amphets. You can't speed up the effects of Lisdexamfetamine so snorting it is useless.
Right but it is still the same active ingredient - dextroamphetamine. Therefore if you take enough of it it will undoubtedly produce euphoric, amphetamine effects.
Sure, you can't snort it, and since it takes several hours to reach peak effects, it is not as "recreational" or "fun" but personally SWIM prefers an extended-release formulation of amphetamine (especially dextroamphetamine) because it tends to make SWIM more productive and euphoric rather than tweaked out and high.
Yes swiy can get high, but i believe it takes quite a while to absorb. It apparantly is just dextroamphetamine which has an amino acid called lysine attached to it. This keeps the d-amp from breaking down until it hits your gastrointestinal tract. thus, making it only active orally.
SWIM likes Vyvanse very much. It's not the same euphoric buzzy high that Adderall gives, but it's a nice high. She likes to take it and get things done. She takes 60-90mg then about eight hours later, another dose anywhere between 30-60mg. She will do this for a couple of days until she's tired and not really as sharp as she wants to be, then let it wear off and sleep. It really makes her focus.
SWIM has found that with Vyvanse though, if she takes it and sits down to get online or do a craft or read etc, she will not get up for hours. If she wants to do housework or run errands she has to make herself start them. Then they are no problem to finish.
SWIM actually just took a dose about an hour and a half ago. She took 60mg about three hours ago and then the last 30mg dose. She won't be sleeping tonight but she will clean the house top to bottom while everybody is asleep, set her hair, and have a nice hot breakfast waiting on everybody when they get up. She also will probably read a whole lot of DF tonight and post a lot too.
SWIM is aware that 120mg will get her higher than the usual 60-90 that she takes. She has taken 140mg in one dose, but no she doesn't reccommend that others try this, as it's probably dangerous. She's played around with it enough to find her own preferences, which she sticks with. SWIY is welcome to take 120mg, but SWIM is happy with the results of her own experiments with it. She takes more over the course of the day, and as Vyvanse lasts a long time, she does get the higher dose over time.
From SWIMs experience with Vyvanse, 100mg was equal to ~40-45mg Adderall. He has to say that though the begining stages of 100mg Vyvanse felt like ~45mg of Adderall, SWIM felt like he was up longer than he would have been on an equivilant dose of Adderall.
SWIM says he was satisfied with Vyvanse when Adderall was desired. He almost would say he'd prefer to have only dextro-amphetamine instead of the mixture of amphetamine salts that make up Adderall.
I shit you not the most vyvanse I've ever poped at once was 14, 70mg capsules I mmmm less than 24 hours each, with my girlfriend. To top it off we had been binging on meth for about 5 days. Lol. All I can say is I felt like a God. And it was so awesome.
I shit you not the most vyvanse I've ever poped at once was 14, 70mg capsules I mmmm less than 24 hours each, with my girlfriend. To top it off we had been binging on meth for about 5 days. Lol. All I can say is I felt like a God. And it was so awesome. I do get hundreds of these things but from a souce I will not say of course. I'm in san antonio texas by the way
Glorifying drug use isnt cool. You almost took a whole gram of vyvanse. Please, no one attempt this. And you were on meth? C'mon man this is a harm reduction site.
In regards to the OP's question 60 mg is the most I have done and i get a nice mild buzz from it. Maybe on a friday I will take 120mg so my toleranc i bit higher than usual. I don takemy meds on the weekend. I will let yall know how it goe if i decide to take them.
Last edited by BowserNasty; 24-09-2013 at 03:28.
Reason: added answer to ops post
around 3-400mg will get you extremely high, but anything sub-100mg wont be pleasurable, and youll only get the effects like foot tapping and tooth grinding and talking too much and stuff. with big doses you still get the bad effects, but you also get an overwhelming urge to sprint everywhere and do everything you think of, plus you feel like you are the king of the world.
The dosage of any amphetamine very dependent on each person. Vyvanse is a prodrug, as it is in its form in the capsule, it's in the form of L-lysine-D-amphetamine, or dextroamphetamine and l-lysine coupled at a molecular level which makes it essentially inactive until taken orally and the stomach breaks the l-lysine from the molecular structure. (This also makes it both an amphetamine and phenylethylamine.) Unless you know how to separate the l-lysine from the d-amp at a molecular level and there is no simple reduction for it so I really just wouldn't, stick to taking it orally. I love IV as a ROA but I know not to attempt Vyvanse.
I have severe ADHD and decided to go on Vyvanse because I was up to 120mg Adderall IR total daily but it's not doing what it needs to. Dexedrine didn't seem to, either. I'm prescribed 70mg Vyvanse every morning and frankly, shit makes me tired. I also had problems with Dexedrine IR making me tired and Adderall IR is the one ADHD med I've been on that hasn't.
The reason I say that size really doesn't play a factor is because I'm 4'11" and 85-90 pounds and just have a naturally high tolerance to amphetamines. My husband is 5'8" and ~165 pounds and was on 7.5 mg Adderall IR 3 times daily and he's switched to 30mg Vyvanse recently as well (it actually works well for him, I'm back on to Adderall IR when the mail gets here, my doctor mailed me prescriptions for my old dose).
My badger is sleepy on less than 3 70 mg capsules, but on 3-4 capsules (210-280mg) her badger feels really nice and very up. Her badger also feels that the comedown is not nearly as harsh as regular Adderall which is not a pleasant comedown at times for her badger.
Start off on the low end, you can always take more later, ya know? With Vyvanse, it doesn't really take from the feeling to dose up if you find yourself needing to since it is a slower release.
Hope this is helpful for some.
ETA: Just to clarify, my listing of Adderall (instant release) and Vyvanase doses were not for comparison or to try and figure equivalencies out. My post was to highlight that height and weight are not always indicative of dosing with some drugs, Vyvanase and other amphetamines are an example (anecdotal and personal so I don't keep winding on) and also to point out that any route but oral is either just wasting, or if an attempt to IV and use some of the "reductions" I've seen will not work and cause at best, no effect and quite possibly a lot of harm if attempted to IV.
And I should add that my body handles amphetamines really oddly and so does my badger, please don't try to gauge doses off of examples I've given here.
Last edited by honeybadger; 09-10-2013 at 00:27.
Reason: Merged doublepost.
The molar mass of amphetamine is 135g, whereas that of lisdexamfetamine is 263. That means that vyvanse is (if fully absorbed) 50% as strong as d-amphetamine.
Adderall's salts are half saccharate (210+135 g/mol for that portion) and half sulfate (96 + 135 g/mol), averaging at about 288g/mol.
Next, let's factor in bioavailability. Oral is between 75% and 100% for adderall, and 28% for vyvanse. If we assume the low end of adderall bioavailability, that leaves us with 34% equivalency, or 100mg vyvanse equaling 34mg of adderall. But that doesn't factor in that the amphetamine is adderall is 75% dextro and 25% levo. If we account for that, that leaves us with about 45% equivalency, or 45mg adderall being equivalent to 100mg lisdexamphetamine, ignoring the l-isomer, which does help to improve some symptoms of ADHD, while not really improving the high or central dopamine release.
What does this mean? It means that people on this thread are wrong to equate lisdexamphetamine doses to be approximately equivalent to adderall doses. At the same time, the fact that it is sustained and steady in its release (it is broken down not all at once, or in an hour like people on this thread suggest, but with first-order kinetics) makes it last longer and might provide the illusion that it is more powerful than amphetamine salts. The fact that it doesn't hit quickly and end quickly might add to this.
SWIM about to enjoy 60mg of the vyvanse, along with a different drug that will undoubtedly interact well with the first one. Is 60mg a good dose for someone with somewhat limited experience and no tolerance to the drug?