Side effects - Mushrooms and Syncope (Fainting/Blacking Out/Passing Out)

[Entropy]

Hi


Me and my friendate 2 grams of dried mexican cubensis (First time trying mushrooms). After about 40 minutes, when the effect is supposed to kick in,I felt a bit nausea (like I expected), but then I passed out and woke up sweating like hell and feelingdizzy/nauseas. What gives ?


I didn't experienceany psychedelic effect except feeling like shit for 2 hours (maybe the blackout suppressed theeffects?)I got some mild effects after 2 hours though (super sharp eye-vision and music sounded louder etc). My friend told me I got blue in the face and was out for about 1 minute. He nearly dialed 911.


Is this sort of blackout a sign of allergic reaction ? I must admit I got a bit scared after that episode, butI am still curious as to what happened.Should I just accept the fact that mushrooms are not for me, or maybetry another time (with a smaller dose of course) ?

[polloloco001]

did you pick the mushrooms wild or some shit

[Softrat]

If you really turned blue then no, you shuld not eat shrooms again. Also if what caused the bad reaction was psilocin or psilocybin, then you may not be able to take any tryptamines as you may have some bizzaro tryptamine allergie.


Of coarse the bad reaction could have be cause by some other chemical in the mushrooms.


If these were wild mushrooms maybe you got the wrong species.

[Entropy]

these were homegrown so the species was correct

[polloloco001]

they could have got contaminated. did you grow them in a really sterile
environment? cuz other mushrooms will grow and shit i think if its not
completely sterile. i have heard of people getting nauseous but that
sounds like you ate poisonous mushrooms.

[Softrat]

Yes I suppose their is some possibility of contamination, but be very careful if you eat mushrooms again. I would recomend staying away from shrooms. But if you do try them again eat only a very very small amount and see what happens.


The turning blue thing is way bad so I would not eat them again.Edited by: Softrat

[thegod1]

That sucks. I think maybe you should try them again becaus a lot of people claim they blackout, also they are really fun.


You should DEFINATLY take a smaller dose next time, maybe your body couldnt handle that much or first time? Im not sure never happened to me so i cant offer much advise on this.


If you do choose to try them again, please update!
Good luck hope all goes well.


Also, try not to remember what happened the first time, dont expect to blackout, think of that as just a first time bad luck or something, dont make yourself trip bad! Edited by: thegod1

[Dogears]

Originally Posted by thegod1

That sucks. I think maybe you should try them again becaus a lot of people claim they blackout, also they are really fun.

Thats interesting cause I have never heard of anyone blacking out from shrooms. I wonder if these people that have this problem are doing some prescription drug that is interacting with the tryptamines in a bad way.

[jatzstoned]

maybe it was something you ate prior to the shrooms, some kind of weird food chemical reaction perhaps

[Phungushead]

I've heard lots of reports of people blacking out from shrooms; generally,
the situation seems to be either (a) it's their first time tripping, or (b)
they took an extremely high dose... either way, it could be that the
experience and the rush is just too much to keep consciousness... one
of many possible explanations. Everyone reacts different, so there's
no way to tell for sure.

If you fasted for a long time before taking the mushrooms, that could
possibly lead to blacking out (especially if you're diabetic or something),
losing consciousness could also be caused by a sudden drop in blood
pressure.

You don't have to do them again if you don't want to... but if you
choose to do so, first of all give it some time before you take them
again, dose lower, and make sure you have someone with you just in
case. There's a good chance that it won't happen again... if it does,
then I would be skeptical of trying shrooms again.

[d2]

Hey everyone, this is the main reason I joined the site, cause someone else blacked-out the same as I did, well twice anyway.

What happens is your brain is overloaded with so many thoughts and feelings from the mushrooms it basically gets overloaded. This only happens to me when I have a bad trip, because I'm tripping my brain doesn't know how to handle the situation so it shuts down to basically "cool off".

This happens in people with a high "vegal" response I think is the word, where you tend to pass out if you are in high amounts of pain, things like that.

I've eaten mushrooms about a total of 8-10 times and only had this happen twice, both happening in bad trips...

I remember the last time it happened we got a call from a random person that found my roommates phone in the parking lot covered in blood and saying that he was walking around belligerantly drunk naked in some random parking lot with no one around...

That was no fun.

[Greenport]

SwiM's platypus was not going to make this thread but apparently it's important enough.

Awhile back the platypus had taken some libbies and a few hours after taking them, it was walking and felt weak. Disregarding it, a few seconds later the platypus blacked out and fell. It hit its head on a wall in the process. Other than freaking out about it for awhile it turned out alright. It assumed that the mushies were bad and moved on.

Not long afterwards, it found a wonderful source of psilocybe cyanescens and had a flippin great time, but it found out that it still gets this weakness/dizziness spell on them occasionally, especially when combined with pot. If feeling weak, it would often ask for some water and upon standing would feel dizzy and have to sit immediately or it would faint. Things would get 'reeeealllyy' trippy for that period of time, as if one was breaking through on DMT maybe (the platypus doesn't actually know, never tried that.) and after the spell would end, it would feel a bit weird for a few minutes then get better (albeit this often sobered it up.)

Now at this point swiM had done some research on the topic, on another popular shroom-related forum and a search brought up a 'lot' of threads with similar inquiries. The basic answer is "it happens", with various people sharing their stories about fainting in various places after taking mushrooms. Now, erowid lists dizziness/fainting as a negative side effect of mushrooms for people with low blood pressure. Maybe the platypus has that but it doesn't really know, and is in good health overall.

It doesn't experience anything even related to this lightheadedness when not on shrooms, ftw. When it was younger it would sometimes faint if it stood up too fast but that was rare and hasn't happened in years.

---

SwiM's question is, has this or something similar happened to swiY or anyone else swiY knows on mushrooms? Or anybody have a more valid answer to what's happening here? It seems from the research swiM has done that it is a somewhat common occurrence.

Reputation Comments on this post:

thanks for creating this thread on this very interesting and educative topic

[riaahacker]

This is quite possible with people prone to low blood pressure issues. 5-ht2a receptor activation causes vasodilation. Heres a reference that might be relevant to swiy's problem.

We have previously reported that (±)-1-(2.5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), a 5-HT2 receptor agonist, induced renal vasodilation in anesthetized dogs. The present study was designed to investigate whether DOI-induced renal vasodilation might be mediated by increased nitric oxide (NO) release/production in renal tissue. The experiments were performed in anesthetized dogs. A 23-gauge needle was inserted into the left renal artery for infusion of drug solutions. Renal blood flow was measured with an electromagnetic flowmeter. The microdialysis probes were implanted into the renal cortex to collect the dialysate for measurement of guanosine 3′,5′-cyclic monophosphate (cGMP) and nitrite/nitrate (NO2/NO3) concentration. Intrarenal infusion of DOI at a rate of 5 μg/kg/min resulted in a significant increase, by 30±4%, in renal blood flow, indicating renal vasodilation. The renal interstitial concentrations of NO2/NO3 and cGMP also increased by 70±6% and 60±6%, respectively. These changes induced by DOI were completely abolished by the intrarenal pretreatment with Nw-nitro- -arginine methyl ester ( -NAME, a NO synthase inhibitor, 100 μg/kg/min) or sarpogrelate (100 μg/kg/min, a highly selective 5-HT2 receptor antagonist). DOI infusion increased urine volume and urinary excretion of Na+, which were also blocked by -NAME or sarpogrelate. These results suggest that DOI caused renal vasodilation due to increased NO release/production by stimulation of 5-HT2 receptors in the kidney. The natriuretic effect of DOI might also be related to increased intrarenal NO production.

THC and the other cannaibnoids in mj also cause vasodilation (think blood shot eyes). This causes a further drop in blood pressure, which might explain why swiy feels very dizzy when combining weed with shrooms.

Reputation Comments on this post:

thanks for taking the effort to find this reference

[dadrone]

Originally Posted by Greenport

SwiM's question is, has this or something similar happened to swiY or anyone else swiY knows on mushrooms?

SWIM can't tell you why it's happening but he can share a similar experience. SWIM got some of the best mushrooms he had ever had. It was actually just two big caps that weighed approximately 4g together total. Amidst quite a bit of marijuana use, SWIM went to the bathroom. No big deal, right?

So next thing SWIM knows he's lying in a bathtub (half in, legs out), face is lying sideways and a spilled bottle of shampoo has formed a puddle of this shampoo about an inch from SWIM's face. This was pretty fucking weird to begin with as SWIM wasn't sure if he was having some weird competely out-of-body hallucination that he had never had on mushrooms... or what... i.e. why the fuck is SWIM laying in this bathtub. Looking back on it, SWIM remembers feeling the wall melting around him as he was urinating and then the shampoo incident is the next known memory. Ok so after a minute or so after waking up next to the puddle of shampoo, SWIM thinks he maybe passed out. No biggie, no bruises or blood on head. So SWIM then walks out of the bathroom and into the living room with his shrooming buddies and blacks out again and does a faceplant right into the coffee table. SWIM doesn't remember it (so it didn't hurt) but the story was that he completely got b-smacked by this table.

Anyways... no explanation except that these mushrooms, aside from the black out sessions, were pretty much badass. And maybe SWIM should've consumed a slight bit less.

[Greenport]

Yeah that's the weirdest part of it is the wall-melting and intensity that happens before/with the blackout. Isn't it bizarre? When it happened the swiM's platypus the first time, it fell and cut its head on the wall. It wasn't bad/deep or anything but there was definitely a mark there for a little bit. And actually come to think about it, swiM's platypus started feeling the lightheadedness too while urinating. It was while walking back that it blacked out.

It remembers when it came to, everything was really crystalline and trippy, as if the mushrooms had increased in intensity by a factor of 1000. A minute later it would get up and be alright. It also remembers not feeling pain or anything from the cut, didn't even know it was there till it looked in a mirror.

Since it has learned to sit down immediately when it feels that way on mushies. Still all the weird effects but at least there's no fall.

[Phungushead]

This has happened to Labrat once. It was about 5 years ago, cubensis
mushrooms, probably in the 3-4g range. Don't really remember the exact
circumstances leading up to the event, except for going into the kitchen
for some reason (which in the house Labrat was living in at the time was
sponge painted with this grayish-blue on white pattern which made for
some extremely trippy visuals). Anyways, next thing Labrat remembers is
waking up in the middle of the kitchen floor about 4 hours later, wondering
what the hell happened, then got up and went to bed and went back to
sleep.

Can't really offer an explanation, but here's another theory to throw out
there... possible correlation to low blood sugar? Don't know if it applies
to everyone, but Labrat usually fasts for 8 or more hours before taking any
kind of psychedelic.

Sometimes on mushrooms Labrat has a tendency to hyperventilate without
really thinking about it... although this has never personally led to syncope,
maybe that could explain some cases.

Just throwing out some ideas

[Greenport]

4 hours later? o.o; the platypus would usually only black out for a minute or so, if that, then come back. Then again that is around a level 4 trip, prolly a little more than what the platypus had.

[Phungushead]

^^Yeah, it was weird.

My guess at what happened is something along the lines of Labrat got up
to go into the kitchen to get some water or something, and maybe look at
the trippy paint job in there. Passed out, and fell to hit head either on a
cabinet (woke up near the sink) or a wall, or the floor just right and got
knocked the fuck out (had a splitting headache the next day, as well as
some gnarly bruises). Labrat was alone at the time (which in retrospect was
stupid), as well as very tired, so just fell asleep.

Still always kind of chalked that one up to not eating for so long, but who
really knows - fainting is kind of a funny thing in general.

[Alfa]

Originally Posted by dadrone

SWIM can't tell you why it's happening but he can share a similar experience. SWIM got some of the best mushrooms he had ever had. It was actually just two big caps that weighed approximately 4g together total.

Do you have any idea what species of magic mushrooms they where?

Originally Posted by riaahacker

This is quite possible with people prone to low blood pressure issues. 5-ht2a receptor activation causes vasodilation. Heres a reference that might be relevant to swiy's problem.

The study shows renal vasodillation. Does anyone know how vasodillation in kidneys relates to fainting?

Originally Posted by riaahacker

THC and the other cannaibnoids in mj also cause vasodilation (think blood shot eyes). This causes a further drop in blood pressure, which might explain why swiy feels very dizzy when combining weed with shrooms.

Indeed. Blacking out on cannabis is quite common, AFAIK this is due to low blood sugar levels.
I wonder if the use of cannabis is not what causes blackouts when on magic mushrooms. Magic mushrooms seem to potentate the effects of cannabis substantially.

[Greenport]

Ohh maybe swiM had it backwards in the other thread, think swiM had said vasoconstriction. Hmm sorry

The platypus should note that at the time it smoked cannabis regularly and never had problems with cannabis alone - also the problem seemed to mostly arise when on mushrooms 'and' smoking weed, but not always. For instance it took a good level 3 trip and was feeling great the whole time (even went for a walk and stuff), until at the end when it smoked a bowl with its friend before going home, and felt weak again and had to sit down. A few minutes later it was alright again and could head home. That was the last time it smoked weed on mushies and subsequently the last time that happened.

[Desertfox]

This also happened to SWIM around 2 years ago, and looked into it because the experience was quite scary. SWIM found this article when snooping around the internet...

Presence of phenylethylamine in hallucinogenic Psilocybe mushroom: possible role in adverse reactions.
AUTHORS: Beck O; Helander A; Karlson-Stiber C; Stephansson N
AUTHOR AFFILIATION: Department of Clinical Pharmacology, Karolinska Hospital, Stockholm, Sweden.
SOURCE: J Anal Toxicol 1998 Jan-Feb;22(1):45-9
CITATION IDS: PMID: 9491968 UI: 98150932
ABSTRACT: The use of mushrooms containing the hallucinogenic substance psilocybin for intentional intoxication is relatively common. Occasionally, this results in adverse reactions with typical tachycardia that is not evidently caused by psilocybin. This study demonstrates the presence of phenylethylamine in the species Psilocybe semilanceata using gas chromatography-mass spectrometry and shows that the amount of this substance may vary much more than that of psilocybin. The highest amount of phenylethylamine (146 microg/g wet weight) was observed in mushrooms from a case of three young men hospitalized because of adverse reactions. Comparison of the symptoms observed in clinical cases of magic mushroom intoxication with those after intake of pure psilocybin or phenylethylamine suggests that phenylethylamine might have a role in the development of adverse reactions to Psilocybe mushroom intake.




SWIM thinks that the low blood pressure, in addition to a high phenylethylamine content and cannabis, caused the dizziness/fainting that SWIM and SWIY experienced . SWIM one day wants to compare different strains and assay them for constituents and corresponding effects.

Reputation Comments on this post:

Good tidbit of info, never would have thought of that.

[Greenport]

Ooh that's very interesting DesertFox Never even would have thought phenethylamine would have something to do with adverse mushroom effects or that it was even formed in them.

^ Wow, this is apparently even more common than the platypus originally thought. Should be interesting to see how many more bees mention this adverse effect with mushrooms.