MAOI and synthetic tryptamines ?

[Sick Jack]

Hi people,

MAOI containing plants or seeds are used for example to make oral DMT active or to potentiate psilocybian mushrooms.

I would know, what are the results of mixing synthetic tryptamines (or even other DMT/psilocybin natural containing stuff) with MAOI as Syrian Rue.

Dosage, side effects, effects' quality and so on. Thanks in advantage for your comments !

[Sick Jack]

Thanks a lot! I know erowid.org pretty well and was more interested in having the opinion of experienced psychonauts

[GDxCAT]

It should work just fine.

I have heard of many experiences of people mixing an MAOI with DPT (something i am going to do soon myself).

I dont really see why it would be any less safe with other tryptamines.
The only ones i would be weary about the the 5 meo's, as they already
require such a small dose and dont always feel safe on the body.



If you are going to experiment with this than let us know how much you took of each substance.



oh and one more thing, take less of the tryptamiine than you normally
would as you dont know how much more potent the MAOI will make it.



peace in the middle east forumers



...cat

[Toltec]

cEdited by: Toltec

[truestbet]

Just so you know, some don't mix well, to be on the safe side, I would start with lowdoses to make sure.Do a search for seratonin syndrome if you don't believe me. I can think of better things to mix than things that are proven to send people over the edge of insanity!

[Sick Jack]

@truestbet

Oh yeah, clear, I don't gamble with the SSRI syndrom, I take it really seriously and that's why I was trying to gather further information on this particular combinations

[RoboCop]

This sounds very interesting Swim has almost tried this with harmala and 5-meo-mipt, but like you said 5-meos may not be the safest for this combination.(although IMO 5meomipt would be the best of the 5meos) I was able to talk Swim out of it until further information was gathered stupid Swim is always getting himself into trouble.

[Sick Jack]

Each person is definitely different
SWIM found 5-meo-mipt for example has been an interesting "social" stuff, but a bit toxic. So SWIM thinks that mixing syrian rue and this rc could lead to really bad reactions....

Eventually a 4-ho-dipt+syrian rue combinations, but SWIM will wait to hear about others experiences with the combination.

[RoboCop]

I change my mind on the 5-meo-mipt combination it could be rather dangerous, seeing some people have very bad reactions with 5-meo-mipt by itself.

[truestbet]

good idea, i think that would be a potentially bad combination. I think the four hos would go better with maois since they are more closely related to shrooms, right? Why do we rarely ever see bad combinations from natural tryptamines like those contained in shrooms? Why are you people taking MAOIs in the first place, a doctor once tried to tell me I needed them but I refused, are MAOIs really that great, or do yousuffer mood disturbances? If that is case for some one out there, maybethey shouldn't be taking tryptamines at all?

[nanobrain]

time to jump in. first off, what would be one's reasons in wishing to potentiate the already orally active synthetic tryptamines?

economy? exploration? if the latter, you are off to pharmahuasca territiry, whereby the psychedelic / physical nature and the chemical effects / pharmacokinetics of the substances and subsequent enzymatic / transmitter interactions are changed significantly. not to mention the very hightened freakout factor.

the selectivity of MAO inhibiton - A/B or both, (ir)reversability, additional trace but active compounds if plant sourced, your diet and metabolism all play a role.

have you personal experience with MAOI's? "SSRI syndrome" or serotonin syndrome as i presume is just one of the health issues of concern, there are many other.

i would avoid unless well versed with the action of each compound on its own, not from what you read on the net, but from personal experience.Edited by: nanobrain

[Nagognog2]

Bongo has been interested in the combination of harmala alkaloids and DPT for some time. He just mixed some DPT.HCl with baking soda and a few drops of water. Then applied heat. Sure enough - the pure DPT volatized as expected with it's classic result. So bongo will soon try 10mg DPT in lemon with 100mg mixed beta-Carbolines orally. Tally Ho!


Bongo will send a postcard from Mars...

[GDxCAT]

Bongo will need a dose much higher than 10mg of DPT for it to be orally active, even with an MAOI.

[Nagognog2]

Bongo is a cautious ape. But thanks for the tip.

[truestbet]

Swimhad a reaction similar to seratonin syndrome once, although it wasn'tcaused by acombo withMAOI, it was caused by a combo of buspirone and a synthetic tryptamine. It turns out some buspar looks like xanax (2mg)bars, andswim thoughthe was taking (1mg)half a bar, it turned out to be buspirone. I guessmy old buddy swimshould havetaken a little closer look. He told me that it was a very bad feeling and he wasn't able to control his own thoughts, and he kept getting caught in these creepy thought process loops that ended upkeepinghim up for 4 days,he was a nervous wreck,he was very upset and mad and everything that happened tohim,and made himextremly paranoid,if he went outside he thought wild animals were going to come after him and attack him, andhe basically did a lot of stupid things for about a week after thathe nowregretsandheis still not right about the whole situation. The only way to help the syndrome calm down, is benzos, so make sure you have a lot of benzo's just in case you go off the deep end. Swim had to take twice the amount of benzos to calm down, and stop running around like a chicken with his head cut off.


This wasyears ago now, and it still frightens me and Swim whenwe talk about it.Bad reactions to synthetic tryptamines are nothing to play around with.

[Sick Jack]

Ok, thanks to everyone for your feedbacks !

I had one single experience with an MAOI, syrian rue, by trying to potentiate an already good dose of hawaiians. Really really bad idea, I was not spiritually preparated for such experiences and had a bad reactions during the trip. The day after, after sleeping a few hours, it was clear in my mind that I had made a big mistake, but that I was lucky, 'cause the "Elements" just tried to give me a (fucking) lesson : "Don't gamble with us, DON'T SIMPLY FUCK WITH US. Be respectful and We will respect you.....:"

SO TO RESUME : combining MAOI's is anyway a risky operation, so it's better to avoid been a guinea pig....

[a-SalviaLover]

Why MEOs are more dangerous to combine than others. I have two doses of foxy and I am thinking of combining it with MAOI. Although I got them ina capsules and it would be hard to split the dose. But I expect sth similar to shrooms to happen I have taken shroomz without a MAOI only twice. And I like the combo although it's too hard.

[Sick Jack]

Hi !

Has anyone experience with the combination of an MAOI and 4-ho-det ?