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Nightshades Atropine plants like Datura(Angel trumpet), Mandrake & Bella Donna

 
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  #1  
Old 16-12-2009, 17:20
b.yond b.yond is offline
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tropane alkaloid - hyoscyamine

So Swim has come accross some pills, they contain 0.125mg Hyoscyamine each. He figured this was the most appropriate forum to post this in, being that the chemical is derived from these beautiful deadly plants.


There are a handful of trip reports on erowid regarding these pills but can't find much information regarding them. There does not appear to be a specific "vault" or any useful information.


One of the reports combined 250mg (swim believes this to actually be -.250mg) and 10mg ambien for what seemed to be a fun dizzy little time with carpet swirls. but without knowing how much ambien influenced this, it doesn't help much.

So swim would like to call out to all for if possible any of swiy's experience

he wants to know about dosage mostly, he expects effects to be similar to eating some good ol' jimson weed. But if otherwise please do tell.

he's researched medicinal dosage and the experienced side effects at this level.

He knows nightshades are not to be F-ed with, but actually knowing the dosage down to the microgram swim is curious as to what he may be able to have from these mysterious circular objects.

please, any information would be beautiful.


questions, comments, and concerns please.

any info

regards
  #2  
Old 16-12-2009, 20:52
rawbeer rawbeer is offline
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Re: tropane alkaloid - hyoscyamine

LD50 is 375mg/kg in rats...just some guess-work leads SWIM to believe you'd need to eat a lot of these to kill yourself.
The problem is that people who 'abuse' tropanes almost always use plant material, which 1) isn't calibrated and 2) contains a variety of tropanes. You could look at a standard dose of henbane, figure the hyo content of the plant, and calculate the amount of alkaloid in a 'dose', but you've got to remember that henbane also contains atropine, more than hyoscyamine in young plants, less in old plants, so this will interfere with your figures.
SWIM proceeds cautiously with tropanes - slowly build up and monitor the effects. He overdid it with the brugmansia once trembled like he was in a meat locker for a couple of hours, but at the right dose it's great.
There are a ton of pills with this alkaloid content - Anaspaz, a few other -spaz's...google hyoscyamine sulfate .125 mg and you'll get a list from drugs.com.
  #3  
Old 17-12-2009, 01:00
b.yond b.yond is offline
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Re: tropane alkaloid - hyoscyamine

Thank you for the response.

These plants are indeed a cocktail of drugs haha, from what swims heard the levels of alkaloids can vary quite wildly though. I'll definitily do some more research into general levels of hyo.

Swim read the rest of the reports available on erowid. One of them concerned a drug containin barbituates and a cocktale of tropanes at 0.7mg tropane alkaloids per pil. He consumed a total of 20 pills along with some opiates. He hardly remembers much and was discovered by his mum in a stupor and brought to bed.

Another swim found quite interesting! The subject reports to have consumed 9.375mg hyoscyamine, and 300mg quetiapine(which I believe was nightly) and experienced nothing at all. swim is intrigued as qeutiapine is an anti-cholinergic compound as well, swim would think if he took enough hyo to trip and then took some quetiapine he'd be a looney tune for sure!

The most informative dosage wise was one with a subject ingesting 3mg of hyo, and 12 hours later 4.5mg he got the phantom cigarette effect after his first dose, im sure there was more weird things as well. After his redose, his mind fabricated an entire party in his house!

So as it appears, and as you have stated (the LD50) dosages shouldn't be of much danger. He is holding off on the experiments for a little while, he enjoys doing research.

Last edited by b.yond; 17-12-2009 at 01:00. Reason: I always spell atleast one word wrong >:(
  #4  
Old 17-12-2009, 02:59
rawbeer rawbeer is offline
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Re: tropane alkaloid - hyoscyamine

SWIM has also heard that opiates go very nicely with tropanes, if you can get any. SWIM likes cannabis with a very small amount of brugmansia, although it can be a bit scary the fist few times.
And if you ever get sea sick, you're set.
  #5  
Old 17-12-2009, 05:02
b.yond b.yond is offline
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Re: tropane alkaloid - hyoscyamine

Those both sound like things swim would like to try, he happens to be on vacation right now. Perhaps he'll just save these gems and bring em home. Too bad he doesn't know where to get opiates around here.

as pertaining to the cannabis. Swiy says it's scary the first few times? does the cannabis have a powerful potentiation on the tropane's halucinations or body effects? or does the tropane alk potentiate the weed and make one uber stoned?

thank you very much for your replies



edit:
found this thread
http://www.drugs-forum.com/forum/sho...d.php?p=725584
in summary of above thread, no recreational value, still going to dig some more, wiki says its weaker than scopolamine but stronger than atropine.

Last edited by b.yond; 17-12-2009 at 16:20.
  #6  
Old 17-12-2009, 18:53
rawbeer rawbeer is offline
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Re: tropane alkaloid - hyoscyamine

The brugmansia adds to the psychedelic dimension of the cannabis considerably, but it also adds to the paranoia, and causes some weird sensations...'crackling' is the best description SWIM can think of, and sometimes some weird twitching. SWIMs first try, he used way too much brugmansia and wound up cold and trembling, so after that he started smoking brugmansia one puff at a time, wait a few minutes, add another puff - he found for him about four lungfulls is enough (he reccomends this research method to find yr personal dose w/ brugmansia).
The paranoia largely comes from the knowledge that this is such a potentially dangerous plant, but once you feel the effects a couple of times and know what to expect it pretty much goes away and you can enjoy the weirdness for what it is. The sound of crickets chirping outside became fascinating. SWIM likes to just sit there, maybe close his eyes...it's hard to describe the effects, it is very much like it just cranks up certain aspects of the high, the trippier effects, but there's also a distinct signature from the tropanes that's hard to describe (SWIM hesitates to use too many 'trip' comparisons as it isn't really like hallucinogens like LSD). It is also an aphrodisiac, quite a good one. Can't say how this info would translate to your pills, but if you're interested in tropanes this seems to be the safest route, smoking brugmansia. SWIM has still never eaten any tropanes and never would unless in controlled medical doses.
  #7  
Old 17-12-2009, 21:35
Thirdedge Thirdedge is offline
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Re: tropane alkaloid - hyoscyamine

Please keep in mind that exceeding the recommended medicinal dosage of any Tropane could be deadly. While a measured pill is certainly safer than using plant material of unknown make up, at the end of the day your still ingesting a deadly poison, which is not generally considered recreational. Any recreational effects experienced are likely accompanied by straining of the heart and liver.

While Tropanes do boost the effects of cannabis or opiates, a safer option would be too just consume more cannabis or opiates to begin with. If you want to add a 'psychedelic edge' to your stone there are numerous safe and effective substances to use for this purpose.

Personally swim would discard those pills and just get some mushrooms or similar, but each to their own I guess, please be careful.
  #8  
Old 17-12-2009, 22:18
rawbeer rawbeer is offline
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Re: tropane alkaloid - hyoscyamine

Never hurts to remind everyone of how dangerous these things are - but SWIM is curious about your 'safe and effective' things to add to cannabis to potentiate its psychedelic effects. To what are you referring? SWIM has a few guesses (salvia jumps to mind) but is still curious.
  #9  
Old 17-12-2009, 22:47
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Re: tropane alkaloid - hyoscyamine

Quote:
Originally Posted by rawbeer View Post
Never hurts to remind everyone of how dangerous these things are - but SWIM is curious about your 'safe and effective' things to add to cannabis to potentiate its psychedelic effects. To what are you referring? SWIM has a few guesses (salvia jumps to mind) but is still curious.
Swim was not so much meaning things to add to a spliff, but more things to take alongside cannabis. Surely ingesting substances such as mushrooms, LSD, cacti, Salvia etc alongside Cannabis would be a more rewarding option than Tropanes?
  #10  
Old 18-12-2009, 00:11
b.yond b.yond is offline
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Re: tropane alkaloid - hyoscyamine

Swim mostly enjoys the novelty of the pills. He doesn't have a large amount or anything. Swim was thinking about having a couple experiments with MJ, opiates, possibly sex. If he gets them accross the border. He does not intend to swallow a hefty dose and talk to to dead relatives. Swim has been there done that with diphenhydramine.

Swims beginning to wonder however if this novelty of his is worth trying to bring home.

diphenhydramine and the tropane alkaloids produce similar effects, except the tropanes will kill you a hell of a lot easier. Is there anythiing special about hyoscyamine that swim could not benefit from diphenhydramine. Swim is starting to think he should use them to aid in sleep while hes on vaca and toss em, or just toss em, maybe trip.... but toss them...

SO

diphenhydramine vs. hyoscyamine
???

Last edited by b.yond; 18-12-2009 at 00:18.
  #11  
Old 18-12-2009, 00:37
rawbeer rawbeer is offline
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Re: tropane alkaloid - hyoscyamine

The 'classic' hallucinogens, along with salvia, are nice in SWIMs opinion (and more rewarding) but tropanes have a special twist to them - and a two-hour brugmansia 'mini-trip' is a lot more manageable than any of these except salvia, which is too different to deserve comparison. SWIM smokes brugmansia maybe a few times a year, and never eats it or anything, so he's assuming this isn't too dangerous. He uses very controlled doses from consistent source. And it tastes sooo good.
SWIM also feels the need to come to some sort of terms with these deadly plants because they've played such a huge role in our history and myth, and he desires to understand such things. But he doesn't feel the need to enter deep into delirious tropane hell - just a glimpse of the flames.
  #12  
Old 18-12-2009, 02:52
b.yond b.yond is offline
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Re: tropane alkaloid - hyoscyamine

after much thought swim thinks he's going to try and have some fun with these tonight. He's read up on dosages and doesn't even have enough so it would seem to full blown lose touch with reality. Hopefully swim enjoys, he does enjoy the occasional dph trip. Swim feels theres no point trying to sneak these over the border.


this thread has sparked an interest in smoking brugmansia for swim


of course anyone reading should keep in mind tropanes are highly dangerous, and infact deadly. Swim has manufactured, measured amounts and not enough for harm, he'll report back.




UPDATE:
Swim took roughly(one of the tabs had been split) 1.8mg Hyoscyamine, swim had eaten a couple hours prior.
In about 1.5 hours swims mouth was drier than a dessert. another hour followed and that seemd to be the only effects, that and his eyes felt very heavy. He checked in the mirror and sure enough his pupils were saucers.

Not getting much out of the experience swim decided to ingest 10mg Zolpidem and 1.5mg Lorazepam. Figured he'd get some niiiiiice sedation, drink a lot of water, and crash.

Afterwards swim went on a quick walk around the block to have a cigarette and he noticed thats plants and cacti were twitching at random, it was not highly noticeable nor frequent.

Back at home he went to bed after a glass of water. He started seeing shapes of things, there was a large scorpion on his ceiling crawling around!!! and lights playing tricks, nothing too intense. He also had the odd aural distortion, a crackling, maybe a voice not so much though. He fell asleep quite comfortably and had very vivid dreams all night. Swim awoke feeling refreshed early in the morning, his pupils were still saucers! and I believe they are now!

A novelty indeed.

Update again: Swim ingested 150mg dph, and he tells me there's intense synergy. Swim did some digging and the half life is 4 hours for hyoscyamine, Swim is experiencing distortion in the visual field.
Swim tells me hes going to have an interesting day today.

Last edited by b.yond; 18-12-2009 at 18:18.
  #13  
Old 21-12-2009, 20:37
Jasim Gold member Jasim is offline
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Re: tropane alkaloid - hyoscyamine

I would remind anyone considering experimenting with these dangerous hallucinogens to Use A Sober Sitter!!!

The hallucinations produced by the tropane alkaloids are very realistic and even the most experienced psychonauts have difficulty discerning reality from hallucination. Even if one plans on staying locked up in a room and playing it 'safe' these chemicals can severely affect judgment and rational thinking.

Given the intensity of the hallucinations produced by these drugs and the health risks associated with them, only a fool would knowingly ingest one of these chemicals lightly. Do your research and Use A Sitter!!!
  #14  
Old 18-01-2010, 23:47
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Re: tropane alkaloid - hyoscyamine

10 mg of hyoscyamine is the minimum reported lethal dose in humans. So be careful.

I wouldn't take any more than 1 mg if I were you. SWIM uses hyoscyamine all the time to potentiate the effects of mescaline and other psychedelics, but he uses doses of 100 micrograms or so, usually as Datura stramonium seeds (2-5 seeds usually). Messing around with doses above 1 mg is really asking for trouble. With 10 mg being a possible lethal dose, albeit the minimum, you’re really getting into a dangerous area.

If you take much more than 1.5 mg, you can experience delirium. The delirium can be so bad that you have no idea if what you’re seeing is real or not, and your memory is extremely short so you might forget you took the pills, and then take more, and then more, and then more and then die. It messes with your short term memory.

Actually though, scopolamine is more dangerous mentally than hyoscyamine is. The delirium produced by scopolamine is much worse. Either way, delirium is a very dangerous state to be in.

Hyoscyamine is a great anti-nausea medicine and potentiator of other psychedelics when used in safe doses. But when toying around with it to produce delirium, you’re getting close to the lethal dose. Delirium is considered a sign of overdose, and the medical community is NOT joking about that. Delirium is a warning sign that you might be about to die. Delirium happens right before a lethal dose is taken.
  #15  
Old 24-05-2013, 23:19
Hp Rush Hp Rush is offline
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Re: tropane alkaloid - hyoscyamine

I have the exact same pills and they dissolve under the tongue and are sweet as hell but one day I wanted to trip so I took 6 then worked my way to 9 and boy I was fucked up eyes deathly red mouth didn't have a drop of liquid they make you retain water and you don't sweat be careful but I I.v my dilaudid and take 2 of these tablets under the tongue and I nod for so fucking long they are an excellent potentiatior I love em. I just did 6 mg of D and took 2 and I feel great as we speak

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adderall, atropine, belladonna, diphenhydramine, drugs, hyoscyamine, opium, psychedelics, snorting, tropane, weed

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