Zyban and XTC...

[xpr´k]

im planning on quitting smoking soon'ish and one method i know is quite effective is zyban. I got told however zyban is actually an antidepressant which showed some interesting results on the smoking behaviour of the patient and thus got released as an antismoking pill. He also said it didnt really work all that well as an antidepressant but i cant confirm that.


Here's what i found online about zyban :
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DRUG CLASS AND MECHANISM: Bupropion is an antidepressant medication that affects chemicals within the brain that nerves use to send messages to each other. These chemical messengers are called neurotransmitters. The neurotransmitters that are released by nerves are taken up again by the nerves that release them for reuse. (This is referred to as reuptake.) Many experts believe that depression is caused by an imbalance among the amounts of neurotransmitters that are released. Bupropion is unrelated to other antidepressants. It works by inhibiting the reuptake of dopamine, serotonin, and norepinephrine, an action which results in more dopamine, serotonin, and norepinephrine to transmit messages to other nerves. Bupropion is unique in that its major effect is on dopamine, an effect which is not shared by the selective serotonin reuptake inhibitors or SSRIs (e.g. paroxetine, Paxil; fluoxetine, Prozac; sertraline, Zoloft) or the tricyclic antidepressants or TCAs (e.g. amitriptyline, Elavil; imipramine, Tofranil; desipramine, Norpramin).


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My guess is anyone taking these pills should really stay of MDMA as it seems to work in the same area of the brain . Ive read somewhere dopamine is what damages the serotone receptors after XTC has made you brain use up a far larger then usual release of seretone .
Zyban increases the amount of dopamine in your brain so logicly it would increase the damage . So if anyone here is taking zyban or planning to take it , remember to not drop while your doing it.

if my assumptions are incorrect please feel free to correct me . I'm still trying to understand the workings of XTC .

[Nagognog2]

That is a form of speed with no fun attached. It will make you feel like crap and wire you and cause you many sleepless nights. Forget it. Just quit the smokes and don't belive the hype of how terrible you will feel. I've seen many folk quit smoking and go through no withdrawl. So can you. Or don't. Take Zyban and become a basket case. It's speed and it's "supposed" to make you feel better. Uh huh...dogfood it will. It's a derivitave of diethylpropion: A diet pill. Yes it will mess your serotonin up. Yes it will mess your dopamine up. But remember you are giving up smoking! In exchange? You become a raving, sleepless nutcase! YaHoo!!

[xpr´k]

well i used it to quit smoking 9 months ago and i had none of the side effects you describe . In fact it worked beautifully , i had 0 craving for sigarettes and it kept me clean for 6 months.


I made the mistake however to think i could smoke weekends only and after my holiday on which i smoked each day i just started again. Im now planning to quit again usingZyban (got someleft)after my B-day which will also be celibrated with the taking of some X .


I recently re-discovered X after being 6 years clean and ive researched it alot since then . In doing so i also realized the combo of the 2 might be dangerous so i thought ide share the info.


I decided for myself to leave at least 2 weeks between me taking X and starting up with the Zyban (prolly 3 to be safe). I'm also taking alot of care prior , during and after rolling to minimize the bad effect X has on my body .

[Nicaine]

Originally Posted by xpr´k

im planning on quitting smoking soon'ish and one method i know is quite effective is zyban. I got told however zyban is actually an antidepressant which showed some interesting results on the smoking behaviour of the patient and thus got released as an antismoking pill. He also said it didnt really work all that well as an antidepressant but i cant confirm that.

Correct on the part about smoking. As far as how well it works as an antidepressant, that depends a lot on who's taking it. For those who suffer from lack of energy, lassitude, unmotivated type of depressions, it works very well. For the anxious or other types, it tends to work poorly. It's basically a stimulant that works on dopamine/norepinephrine, while most other antidepressants work on serotonin.

Doctors tend to knock bupropion these days because they're brainwashed by drug company advertising, and bupropion is now a generic drug for the most part. Doctors want to push the latest/greatest and most expensive drugs, and they get free pens/watches/pads of paper with the names of new drugs written on them. "Old drugs" almost always get knocked. Of course, the older the drug, the more its safety profile is known, but who pays attention to that right? Edited by: Nicaine

[quinone]

I took wellbutrin (zyban) for depression and it was easily the best
SSRI ive taken (and i've taken most of em lol). There were none
of these effects that nago speaks of, but im sure those side effects do
exist in some people. It was the most 'natural' synthetic
mood-enhancer I had taken (over the period of 3 weeks I eventually just
felt naturally happier and less depressed, as if it was in me the whole
time, but I had just finally realized it).



When it comes to quitting smoking, zyban is helpful, but having quit
smoking myself, and seeing my father (a smoker of 40 years) quit, I can
easily attest to the fact that zyban, nicoderm, etc. etc. are more or
less a scapegoat so that ppl can 'feel' like they are quitting.
If you want to quit smoking, you have to really WANT to, and that means
just stopping straight up. Zyban and others just give ppl an
excuse to feel good about themselves for 'trying' to quit, but often
doesn't reflect that persons genuine desire to quit. If you want
to quit, lock yourself in your room for a week with some drugs or porn
or something, and just be a man and deal with the withdrawl symptoms
(which on a physical level are probably no worse then a bad flu), on a
mental level .. lets just say you'll find out if you have a strong mind
or not by the end of that week.

[george]

Wellbutrin/Zyban felt much like an amphetamine to me although it didn't give me euphoria at all. Edited by: george