Combinations - Dumb combo? Probably.

[Jimmyyyy]

Ok so recently SWIM and a friend have tried doing pills and stuff. SWIM took about 2mg lorazepam, 10mg of oxycontin, and 2mg of xanax(It was probably a bad idea of SWIM to take all this, right?). After like 30 minutes SWIM was sitting in his garage bathroom freaking out hearing voices from just about everywhere. It was really creepy.

Just wanted to know, has this ever happened to SWIY?

[Boca Bitch]

No.. because SWIM is aware of the danger of combining benzodiazepines/alcohol/barbiturates with opioids. Your monkey was onto a hunch with this being a bad combination. Taking oxycontin with alprazolam (Xanax) and/or lorazepam GREATLY increases risk of respiratory depression, which = death.

Combining lorazepam and alprazolam isn't particularly dangerous in itself.

[Jimmyyyy]

SWIM was like paranoid out of his mind loll. Good thing SWIM didn't over do it. It was kinda fun though, in a scary way.

[psyche]

Well that sounds like SWIY overdid. Good thing is SWIY didn't die.

Even bad memories turn golden with time. It ain't a reason to get in that kind of situations again, though.

[ninjaned]

SWIM took about 2mg lorazepam, 10mg of oxycontin, and 2mg of xanax(It was probably a bad idea of SWIM to take all this, right?). After like 30 minutes SWIM was sitting in his garage bathroom freaking out hearing voices from just about everywhere. It was really creepy.

Odd. This isn't necessarily a smart combination, however it's not one that should have cause voices and paranoia as swiy mentions later. Both alprazolam(xanax) and lorazepam should stop paranoia and voices, unless swiy received the paradoxical effects of benzo's. The opiates shouldn't have done anything with paranoia or voices either. Any opinions from others?

[This is bat country]

Originally Posted by ninjaned

Odd. This isn't necessarily a smart combination, however it's not one that should have cause voices and paranoia as swiy mentions later. Both alprazolam(xanax) and lorazepam should stop paranoia and voices, unless swiy received the paradoxical effects of benzo's. The opiates shouldn't have done anything with paranoia or voices either. Any opinions from others?

Backing this up. SWIM's taken a couple vicodin and more benzos than that for euphoric purposes.

After a quick look, it is as I suspected:

pupbme-d id 8262890

A review of the published case reports of adverse behavioral episodes or unexpected psychopathology in patients taking benzodiazepines was undertaken in an attempt to determine if these adverse or unexpected events are more likely to occur with alprazolam when compared with other currently marketed benzodiazepines. Adverse behavioral phenomena and unexpected psychopathology were divided into the following categories: (1) anger or violence, (2) impulsive, suicidal, or self-harming behavior, (3) depression, (4) mania, (5) schizophrenia, (6) withdrawal syndromes and (7) physical dependence and abuse liability. It is difficult to draw conclusions from this literature because of the limitations of spontaneously reported cases and the lack of epidemiologic studies. Despite these limitations, it appears that some differences between alprazolam and older benzodiazepines may exist. The older benzodiazepines are more commonly reported to have adverse events than alprazolam (with the exception of mania or hypomania). On the other hand, worsening in post-traumatic stress disorder and an increase in impulsive behavior in patients with borderline personality disorder have only been reported in patients receiving alprazolam. This is probably explained by the fact that only alprazolam has been used to any great extent in these conditions.

Lots of neuropharmaceuticals can exhibit paradoxical effects. It would be stupid to combine opiates and benzos because opiates can cause nausea] and sedation and benzos cause sedation. You could end up drowning in puke. Most likely wouldn't happen at what seem to be relatively low doses, but still, a possibility based on various factors.

Your friend should be careful using benzos in the future. SWIM has experienced paradoxical effects that didn't include creepy voices, more personality and behavioral disturbances, but those intensified as his usage increased, and his usage increased as those changes intensified. Mind yourself.

[Jimmyyyy]

It wasn't so much creepy voices. It was like SWIM was hearing SWIM's friend who was actually passed out on his couch but the voices were just so real sounding that SWIM kept looking over his shoulder.

SWIM is a total noob when it comes to drugs so that's why he came on here (: awesome site with lots to learn haha.

[This is bat country]

Originally Posted by Jimmyyyy

It wasn't so much creepy voices. It was like SWIM was hearing SWIM's friend who was actually passed out on his couch but the voices were just so real sounding that SWIM kept looking over his shoulder.

SWIM is a total noob when it comes to drugs so that's why he came on here (: awesome site with lots to learn haha.

Well, I don't know about most people, but lorazepam has always been a benzo that SWIM avoids like the plague. 2-4mg + booze = somewhere near blackout. This doesn't happen with any other common benzo in far larger doses, and I believe it has something to do with the hepatic processing of benzos (lorazepam isn't processed in the liver in the same manner as say, clonazepam).

lorazepam also leaves swim feeling sketched out before he reaches the blackout phase, and also the hangover feels that way too. so, I suppose it parodoxically increases anxiety... none of the other benzos do, though.

[Jimmyyyy]

Well this morning before class SWIM took 2mg lorazepam and he didn't feel anything. He thinks he somehow has a high tolerance for these things even though he hasn't done them until like 3 days ago. It makes SWIM sad. ): lol. Oh well, at least he gets them free

[frankblank]

too much benzos make you forget the whole thing anyway. I had a very weird experience combining paroxetine and heroin before. made me kind of flip out, shaking and talk to myself out loud (i do that already though). didnt remember much, but was told so by others.

[frasorto]

shit that sounds like a chill night.i would of taken the 3 seperately last longer that way

[Jimmyyyy]

Hahah it kinda was. SWIM would have but he's really inexperienced with pills. He prefers to blaze upppp hahaha

[frasorto]

Originally Posted by Jimmyyyy

Hahah it kinda was. SWIM would have but he's really inexperienced with pills. He prefers to blaze upppp hahaha

yea and wen you take xanax you just wono keep getin more fucked up

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[Phuzed]

That's a dangerous combo for reasons already mentioned above. SWIM would personally have been feeling sick with that much in him. Everybody is different but I'd say SWIY is lucky to have hearing "weird voices" as the worst thing that happened.

All I can say is be careful. It's always a good idea to research the drugs SWIY might take before you take them. A quick search on these forums will most likely have answers to any questions you have. SWIM has sad stories of people he knew that died because of taking dangerous dosages.

Experimenting with drugs can be fun times, but it's important to research starting dosages. Experimenting with dangerous combinations is never a good idea, especially bad when brand new to the particular drugs.

Anyways, Have fun. Be safe.