Getting doc to write for norco

[Beltane]

Saw a doc today and told him I've been taking norco 10/325 at 3 - 4 a
day. Told him I needed more. He wrote for 5/500's @
4/day. So I want to tell him something like 'I need to take up to
8 of those a day for them to work and that's too much tylenol for my
liver.' I'm wondering if that might freak him out and if there's
possibly a better way to get him to go w/ 10/325's instead of
5/500's. Thoughts?



Thanks-



- B

[daveman]

hes probably trying to get you off them, that is why hes lowering your doseage so you can quit.

[Zandorf]

i would say you best bet is to go with it a day or two and complain
that you are having really bad pain on his recoemnded dosage. I'm not
sure but i think you can work your way up to 10/325s or better by
repeating this as necessary.<!--
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[Beltane]

Just so I know, what's better than 10/325? I mean, I know there's
percs, OC and dilaudid. I thought 10/325 is the best of the
vicodin-type pills.



I called him and he said he was writing for what was cheapest (5/500)
as I didn't have health insurance he was trying to help me out.



Thanks-



- B

[daveman]

5 500's are 5mg hydrocodone, 500mg acettaminophen (sp?), the 10 325 are 10mg hydrocodone 325 acetaminophen, more hydrocodone the better =]

[McDiggy]

There is a new hydrocodone/acetaminophen combination available called
Xodol that is 10/300, but it's brand only. A safer alternative
may be Vicoprofen which is formulated with ibuprofen rather than the
hepatically toxic acetaminophen. 4 grams of acetaminophen a day
is the recommended ceiling, anything over 10 grams is just asking for
liver failure after a sustained period of time. The ceiling for
ibuprofen is 3200mg/day and vicoprofen is formulated as 7.5/200, so you
can SAFELY take 16 of those a day vs. 8 vicodin/lortab a day.



FYI, I'm a 3rd year pharmacy student and I'm facinated in clandestine
drug synthesis and this is my first post. I'm not a drug abuser,
just interested in the culture simply due to a fascination with
it. I'm not going to be able to, or even try, to get people to
not abuse drugs, but if I can save a person from liver failure, I've
done something good.

[Beltane]

Cool, thanks for the info. So 4 grams of acetaminophen is the
recommended ceiling. SWIM, when he can't get norco, he takes up
to 16 5/500's. Usually this only goes on for 3 days in a row w/ a
week or so between and this is the upper end of his usage.



Questions: roughly how bad is that level of acetominophen on the
liver? Does liver damage "repair" itself during breaks in between
or is there it more like hearing where it degrades never to return?



"anything over 10 grams is just asking for
liver failure after a sustained period of time."



- Can you commone on "a sustained period of time."?



Thanks-



- B



edit: another question for a pharmacist. SWIM has no health
insurance and so pays for his hydrocodone out of pocket. What's
the most cost effective (and lowest acetominphen) route? Would it
be the norco 10/325's?



P.S. If SWIM were home he'd be doing extractions, but he's up in the mountains


Edited by: Beltane

[McDiggy]

Generally, the LD 50 is about 400 mg/kg. That means the lethal
dose for half the population is 400mg per kg of body weight. This
is from pure liver necrosis. If you take half that over 1-2
weeks, it will slowly deteriorate your liver. A good thing to do
is to take the GERD remedy Tagamet (cimetidine) because it has been
shown in studies to decrease liver tissue death in mice that were
overdosed with acetaminophen:



http://jpet.aspetjournals.org/cgi/co...stract/224/3/5 08



The ceiling of 4000mg is a very conservative estimate that indicates
the amount floating around in your blood that is needed to kill a small
percentage of the population. If I had to guess, I'd say a
one-time dose of up to 8 or so grams of acetaminophen won't kill you,
but I wouldn't repeat the dose for over 2 weeks, if not longer, to give
the liver some time to recoup. If I were a druggie, I'd just take
some oxycontin, it's safer.