Health - How to minimize mephedrone side effects

[Synesthesiac]

Mephedrone has been shown to cause a vast array of side effects in a lot of people. Some severe, some not. This is a list that swim has created from what he has noticed from personal experience and information online on how to minimize the side effects and how to use meph more safely. Roughly in order of what I consider importance.


A) Drink LOTS of water when you are on meph. Swim finds it can suppress your thirst, and if you dont drink frequently then the side effects can get very bad very quickly. Drink a pint or so of water before you use meph, and drinking about a pint or half a pint every hour while using meph would be a very good idea. The occasional energy drink with sugars and salts in would be a good idea too, aswell as plain water.

B) Do not mix meph with large amounts of things that dehydrate you (alcohol is one of these). Many side effects seem to be caused by this combo. Infact mixing mephedrone with any other drug is not to be recommended at all, as interactions have not been studied at all.

C) Ensure you have eaten well before, and have good vitamin/mineral levels by either taking a supplement of having a healthy diet. Magnesium seems an especially helpful supplement to avoid meph side effects (tight chest, gurning, etc). Eating after or during a mephedrone session also helps tremendously. Eat plenty the next day, as your metabolism has probably been very high the night before due to the meph.

D) Do not snort mephedrone, less side effects seem to show when it is orally ingested.

E) Set yourself a dosage limit and stick to it. Most side effects are caused by people doing far more than they originally planned due to mephs moreishness.

F) If you start to get stimulant anxiety on mephedrone, or you take too much and your heart is beating very fast, its a good idea to sit down and chill out. Some benzodiazepines like diazepam are very helpful for relaxing in situations like this, and are probably least likely to cause an adverse reaction with meph than most other drugs.

G) Try to avoid having sex or masturbating while on meph, as meph makes many people very sexually turned on and still able to get an erection but unable to orgasm. This can lead to continual redosing and doing far too much, and alot of frustration.

H) Dosage wise it is very unclear what the ideal dosages are for mephedrone, it seems to vary drastically depending on the person. Test a tiny amount first to ensure there is no allergic reaction. To be super safe and cautious, an oral dosage of 100mg would be a good starting point. Though a lot of users only start showing desirable effects at 200mg. Its definately NOT a good idea to keep redosing for too long as meph becomes very compulsive, and probably best to keep the total in one session to a maximum of 200-500mg.

I) And the final best way to avoid side effects: Dont do any in the first place!

Reputation Comments on this post:

	Good harm reduction
	I agree with everything in the list. Good post.
	informative post which is mobile for people to find quickly. keep it up. :)
	excellent thread idea

[Snowman]

Maybe also a good advice not to mix with other drugs.

[Synesthesiac]

Originally Posted by Snowman

Maybe also a good advice not to mix with other drugs.

Yea, good point, editted.

Thought it should go without saying really but I might aswell add it in.

[runitsthepolice]

Originally Posted by Synesthesiac

Mephedrone has been shown to cause a vast array of side effects in a lot of people. Some severe, some not. This is a list that swim has created from what he has noticed from personal experience on how to minimize the side effects and how to use meph more safely. Roughly in order of what I consider importance.

a) Drink LOTS of water when you are on meph. Swim finds it can suppress your thirst, and if you dont drink frequently then the side effects can get very bad very quickly. Drink a litre or so of water before you use meph, and drinking about a pint or so an hour while using meph would be a good idea. The occasional energy drink with sugars and salts in would be a good idea too, aswell as plain water.

b) Do not mix meph with large amounts of things that dehydrate you (alcohol is one of these). Many side effects seem to be caused by this combo. Infact mixing mephedrone with any other psychoactive drug is not to be recommended at all, as interactions have not been studied at all.

c) Ensure you have eaten well before, and have good vitamin/mineral levels by either taking a supplement of having a healthy diet. Magnesium seems an especially helpful supplement to avoid meph side effects (tight chest, gurning, etc). Eating after or during a mephedrone session also helps tremendously. Eat plenty the next day, as your metabolism has probably been very high the night before due to the meph.

d) Do not snort mephedrone, less side effects seem to show when it is orally ingested.

e) Set yourself a dosage limit and stick to it. Most side effects are caused by people doing far more than they originally planned due to mephs moreishness.

f) If you start to get stimulant anxiety on mephedrone, or you take too much and your heart is beating very fast, its a good idea to sit down and chill out. Some benzodiazepines like diazepam are very helpful for relaxing in situations like this, and are probably least likely to cause an adverse reaction with meph than most other drugs.

g) Try to avoid having sex or masturbating while on meph, as meph makes many people very sexually turned on and still able to get an erection but unable to orgasm. This can lead to continual redosing and doing far too much, and a lot of frustration.

h) And the final best way to avoid side effects: Dont do any in the first place!

While I agree that some of these are good common sense precautions to take and probably wouldn't hurt, is there any reason to believe that doing these things would reduce the occurrence of mephedrone side effects (vasoconstriction, blue limbs, death)? Do we even know why these side effects occur or the mechanism behind them?

I'm just making the point that while doing these things is not a bad idea, it in no way makes mephedrone safe and there is no evidence that it will reduce the occurrance of side effects.

[Synesthesiac]

Originally Posted by runitsthepolice

While I agree that some of these are good common sense precautions to take and probably wouldn't hurt, is there any reason to believe that doing these things would reduce the occurrence of mephedrone side effects (vasoconstriction, blue limbs, death)?

This is from swims personal experience, and the experiences of other people on other forums. The blue limbs seem to be able to be combatted by drinking lots of water, and also eating. The magnesium is common sense (simialr for MDMA) and the other points are fairly obvious, but I just thought I would share so if people are going to use they are going to do it in the safest way possible.

Do we even know why these side effects occur or the mechanism behind them?

Not really, I only know that the above list has helped combat the symptoms on numerous occasions for swim and his friends. And some other people online.

I'm just making the point that while doing these things is not a bad idea, it in no way makes mephedrone safe and there is no evidence that it will reduce the occurrance of side effects.

thats why I put the h) option Maybe should have put that first.

[shadowchaser]

in swims experience not remaining sat in the same position and moving about a bit every now and then pretty much stopped the blue knees.

Reputation Comments on this post:

Excellent point! If that helps a lot, spread the word!

[Snowman]

Blue limbs sounds scary, SWIM will be careful when trying this substance.

[Synesthesiac]

Originally Posted by Snowman

Blue limbs sounds scary

Its not so much the limbs that people have reported turning blue, its specific areas. Mainly extremities like the knees, fingers, elbows, etc, which most people say get very cold aswell. This side effect could be a) lack of water b) vasoconstriction c) auto-immune responce or d) heart/cardio damage of some sort. Drinking lots and eating too do seem to dampen this side effect and also moving about seems to help too. Only a very few people actually have got this side effect, mind you.

[nEone]

Great points. Particularly being vigilant with limiting doseage.

SWIM's method of doing this is to pre-weigh and gel-cap 250mg doses. He has a two-cap limit when he's going to party. He can eat them or snort them, but two caps is the limit. He also has a macro limit of 750mg every month.

Why? Because he's been through a 3 day 4g solo binge, and realized that it stopped being fun pretty early on, and he's annoyed that he wasted good product and time and money and put himself at risk of serious health problems (the 10lb weight loss was all water weight and was gained back as soon as he started eating again - during the three day binge, he ate two small meals.)

SWIM has found that snorting is problematic on 2 levels:

1. The rush is faster, the high is shorter, and the moreishness is FAR greater.

2. The compound dries out the sinuses and SWIM suspects that snorting is only particularly effective the first one or two goes - after which, SWIM suspects that a large amount of the product is simply left in the nostrils/sinuses, not able to pass through the dried out membranes, and thus wasted. (hence larger amounts are seemingly required to get "as high" - creating a false tolerance and a potential for over-doing it.)

In terms of negating the effects of snorting, SWIM has mentioned this in another post, but feels it bears repeating: Invest in a neti-pot. Post-binge, irrigating the sinuses with a saline solution will clear out all of the residual product and help rehydrate the muscus membranes and maintain healthy sinus tissue, thus reducing nose-bleeds and other "flu-like" symptoms.

4MMC isn't a light drug. It's fun, but it's not at all something that can be used daily with any hope of positive outcome. It's not beer. It's not pot. If you're using it daily, please consider tapering back to weekly. If you're using it weekly, consider tapering it back to monthly.

The "specialness" of the drug fades quickly - habitual use only makes that loss come faster. Treat the drug with respect and consider it a treat to be enjoyed on the occasion.

Also - on a qualitative note - SWIM has definitely been seduced by the sexual/masturbatory urges presented by 4MMC. But the truth is - it's a waste of the experience. Music, motion, dancing, even just walking around are all immensely enhanced by 4MMC. Sitting still in a tense position doesn't take advantage of this enhancement, and contributes to possible vasoconstriction problems.

Get up, dance about, listen to some good tunes and enjoy. Jerk off afterwards.

Reputation Comments on this post:

Good advice, adds to the OP nicely

[medicateme]

Originally Posted by Synesthesiac

Mephedrone has been shown to cause a vast array of side effects in a lot of people. Some severe, some not. This is a list that swim has created from what he has noticed from personal experience and information online on how to minimize the side effects and how to use meph more safely. Roughly in order of what I consider importance.


A) Drink LOTS of water when you are on meph. Swim finds it can suppress your thirst, and if you dont drink frequently then the side effects can get very bad very quickly. Drink a pint or so of water before you use meph, and drinking about a pint or half a pint every hour while using meph would be a very good idea. The occasional energy drink with sugars and salts in would be a good idea too, aswell as plain water.

B) Do not mix meph with large amounts of things that dehydrate you (alcohol is one of these). Many side effects seem to be caused by this combo. Infact mixing mephedrone with any other drug is not to be recommended at all, as interactions have not been studied at all.

C) Ensure you have eaten well before, and have good vitamin/mineral levels by either taking a supplement of having a healthy diet. Magnesium seems an especially helpful supplement to avoid meph side effects (tight chest, gurning, etc). Eating after or during a mephedrone session also helps tremendously. Eat plenty the next day, as your metabolism has probably been very high the night before due to the meph.

D) Do not snort mephedrone, less side effects seem to show when it is orally ingested.

E) Set yourself a dosage limit and stick to it. Most side effects are caused by people doing far more than they originally planned due to mephs moreishness.

F) If you start to get stimulant anxiety on mephedrone, or you take too much and your heart is beating very fast, its a good idea to sit down and chill out. Some benzodiazepines like diazepam are very helpful for relaxing in situations like this, and are probably least likely to cause an adverse reaction with meph than most other drugs.

G) Try to avoid having sex or masturbating while on meph, as meph makes many people very sexually turned on and still able to get an erection but unable to orgasm. This can lead to continual redosing and doing far too much, and alot of frustration.

H) Dosage wise it is very unclear what the ideal dosages are for mephedrone, it seems to vary drastically depending on the person. Test a tiny amount first to ensure there is no allergic reaction. To be super safe and cautious, an oral dosage of 100mg would be a good starting point. Though a lot of users only start showing desirable effects at 200mg. Its definately NOT a good idea to keep redosing for too long as meph becomes very compulsive, and probably best to keep the total in one session to a maximum of 200-500mg.

I) And the final best way to avoid side effects: Dont do any in the first place!

The last time my pet did meph he did most of these things. he ate approx 2 hours before hand, drank lots of water, didnt mix and other drugs and took vitamins beforehand. while he didnt really stick to his intended dosage it didnt exceed one gram over about 12 hours. after sleeping he felt pretty normal and didnt experience any bad side effects during or after the exp. these suggestions def help. there is no fool proof soluiton to completely avoiding bad side effects. follow these and youll be better off than if you didnt.

[muckypup]

One to add if you're a woman: go easy on sex. It's easy to spend hours and hours having sex on 4mmc, but several women friends report bouts of cystitis afterwards, especially if toys are involved, because you'll go on for too long and end up rather bruised.

[saj6]

perfect. this thread has all the information i was looking for. thanks, very imformative!

[Addzi]

SWIM had an instance where he got the horn after 500mg of Mephedrone and masturbated for roughly 3 hours non-stop. Let's just say that SWIM was injured from this.

One word. Blisters.

[nEone]

^^ one word: Lube.

[Addzi]

Hindsight is a wonderful thing. Thankfully SWIM isn't scarred.

[AdamNUK]

Mephedrone/Methylone has the same outlook as every other drug out there you abuse the drug and it will abuse you.

Always keep an open mind to the situation and as those great points point out above play it safe before you start mixing and doing shit loads test the waters before jumping in

[psyche]

Originally Posted by Synesthesiac

The occasional energy drink with sugars and salts in would be a good idea too, aswell as plain water.

Maybe some other soft drinks with with sugars and salts would be preferred. Caffeine also dehydrates you, and it increases your heart rate.

[lineartransform]

Originally Posted by Synesthesiac

Its not so much the limbs that people have reported turning blue, its specific areas. Mainly extremities like the knees, fingers, elbows, etc, which most people say get very cold aswell. This side effect could be a) lack of water b) vasoconstriction c) auto-immune responce or d) heart/cardio damage of some sort. Drinking lots and eating too do seem to dampen this side effect and also moving about seems to help too. Only a very few people actually have got this side effect, mind you.

Or the real reason:

e) Sitting in the same position masturbating for hours.

If you look through all the vasoconstriction reports, you'll find one constant. Not a single one reports being in a "club" environment (ie dancing around), and all are very vague on just what precisely they were doing while their knees were turning blue.

It's an indirect effect of mephedrone, not a direct one. Moving around stops this effect completely and totally in my experience.

[nEone]

Originally Posted by lineartransform

Or the real reason:

e) Sitting in the same position masturbating for hours.

Exactly.

The sad thing is - sitting around is REALLY wasting the drug. Body motion really taps into the physical/pleasurable effects of 4MMC.

Put on some music, dance around.

[Durd1e]

Many of the mental side effects of mephedrone swim has found to be due to lack of sleep, SWIM is normally quite resistant to sleep deprivation but not with mephedrone.

So...don't ignore sleep. Stop intake at a reasonable hour, get some sleep. It helps the brain heal itself.

Just on the vasoconstriction note...it helps to take off shoes and socks as these also restrict the bloodflow.

[terrytonic]

Lots of good advice on this thread. Makes a pleasant change from reading all the 'SWIM has done 5g over 72 hours with no sleep and now SWIM feels terrible' type posts.

Taking as little as is needed. Plenty of fluids at the time and some sleep works wonders for this chemical.

[Viscis]

Originally Posted by Synesthesiac

A) Drink LOTS of water when you are on meph. Swim finds it can suppress your thirst, and if you dont drink frequently then the side effects can get very bad very quickly.

This is a very important piece of information, everyone should read this thread. I'd quite like to see it sticky'd.

On a SWIM level:

- Both compounds mephedrone and methylone are diuretic (for SWIM). I find that shortly after taking SWIM urinates alot more.

- When SWIM has been taking mephedrone/m1 swim finds its harder to drink / easy to forget.

- When seriously dehydrated the heart beats faster and stronger increasing the emphasis on it and can quite easily panic SWIM and cause pycosis symptoms such as panic attacks.

- SWIM finds that after taking mephedrone anything he does drink "goes straight through him". Making rehydrating slower.

- SWIM has been hospitalized once due to dehydration/side effects during a methylone session and does not plan to repeat the experience.