It is not my intention to bumb an old Neurontin post, but my cat did want to share his knowledge and method of taking gabapentin
As it has been mention by other users, the body has a difficult time absorbing the gabapentin. It requires the right stomach conditions for oral use, in order to make it more bio-available. my cat recommends eating a meal 30 minutes before dosing, and drinking acidic cola (like coke or pepsi) during the onset period.
As for the dose itself, its tricky too. as other users have stated there is an inverse relationship between the dose of gabapentin and its bioavailability. The more you take at once, the less will be absorbed overall. To help avoid this problem, my cat recommends staggering your dose
For example, you could start with about 600mg. 30 minutes to 1 hour later, take another 300mg. then wait another 30 minutes to 1 hour to take yet another 300mg. and continue this pattern until you reach your preferred state, or your preferred dose. Seeing as gabapentin is safe in large amounts (as far as overdose goes), my cat usually stops when he's reached 2400-3000mg.
This will help avoid the decrease in bioavailability when more is taken.
Onset period usually takes about 1 to 2 hours.
Sometimes longer. So, if you follow my cat's method above, dont worry if your not feeling it yet, keep following the pattern until about the three or four hour mark. By then you should know if its working.
In addition to eating a meal before dosing, my cat recommends eating a small snack every time you take more
, or every other time. This will increase bioavailability