the MAOI’s thread

[genaro]

Ok, here are a few well known substances withMAOI properties:


Peganum Harmala (syrian rue)& Banisteriopsis Caapi(contain harmine, harmaline andterahydroharmine: these arethree potent MAOI-A chemicalswhich also have hallucinogenic properties in high dose)...Probably the best plants one can use for making ayahuasca.


Passifloraincarnata (passion flower) contains beta-carbolines (including some harmine), it is psychoactive but probably not hallucinogen (has an MAOI activity and acts as an antidepressor and relaxant). Oral dose (as a tea) for MAOI activity would have to be pretty high asthis plantisn't much concentrated: 250g dried plant at least (from a calculation I did make)...so achieving MAO inhibition by using passion flower would require great quantities, much better use peganum harmala seeds or banisteriopsis caapi vine.
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Yohimbe (contains yohimbine)...said to have some MAOI properties, but I don't think it would be safe to use for this purpose (as it also has some strong cardiovascular effects)


Moclobemide (apharmaceutical MAOI-A)...has been used succesfully as an IMAO for ayahuasca preparation.





And now, here are a few other ones I'mextremely curious about:


Harmol


Harmalol


Harmane


Does any one have any infoabout these last three chemicals ? Any experiences with these ?


How much of each do you need to achieve MAO inhibition ?(I belive doses to be pretty small, like a few milligrams)


Would they only have MAOI properties or would they also have hallucinogenic effects in high dose (just like harmaline has) ?








Edited by: genaro