Combinations - Kava (tranquilizer) and Kanna (SSRI anti-depressant) - Drugs Forum
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Old 07-06-2008, 02:30
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Kava (tranquilizer) and Kanna (SSRI anti-depressant)

Swim's experiment has changed slightly, since he no longer has access to cocaine. Instead, how about kava and kanna?

As a tranquilizer, kava potentiates GABA activity but does not alter dopamine or serotonin.

As an SSRI, kanna works initially as a stimulant with an increase in energy, but mellows out giving a gradually fading euphoria. The main active ingredient Mesembrine is a serotonin reuptake inhibitor, increasing the levels or serotonin.

Hopefully the kanna will provide enough stimulus or euphoria to counter-act kava's tranquilizing effetcs, but may result in a crash later on.
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kanna, mesembrine, sceletium tortuosum

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