An Opioid Detoxification Experiment with Ketamine (by VIAOV)
http://junkiesunion.blogspot.com/200...--------------
When I first encountered this drug, it was back in the late 1990s. It had just emerged on the club scene in South-East Asia. I procured a gram of Ketamine powder/crystals from a 10ml vial of Ketalar (racemic Ketamine). I had been researching into the use of NMDA-Antagonists like Ketamine for attenuating an opioid addiction. At the point of purchase, my habit was an estimated 480mg of Morphine PO/day. Abstinence symptoms (Withdrawals) presented themselves at approximately 8-12 hours after my last Morphine dose. To determine the efficacy of Ketamine in attenuating an opioid addiction, I set about a little experiment that spanned 5 days. The experiment began 4 hours after the last Morphine dose. Each day, once a day, approximately 200mg of racemic Ketamine was insufflated. The dissociative effects can be described as a typical "K-Hole" experience. From the first day I started this experiment, I ceased all opioid use. For the first 2 days I had very minor opioid withdrawal symptoms. For the remaining 3 days of the experiment, I had little to no withdrawals. Day 6 I assessed my symptoms. Not only did I experience little to no withdrawal symptoms from ceasing opioid use, I no longer had any cravings for opioids. On the 8th day, I took a relatively low dose of Morphine and noticed a very strong opioidergic effect, as if my tolerance had been reset.
Despite the rise in abuse of this drug, Ketamine appears to be very promising in the treatment of not only opioid addiction, but also alcoholism, treatment-resistant depression and chronic pain. Scientific data and abstracts will be posted here shortly...
NOTE: Interestingly, a similar experiment was conducted with the low-medium affinity NMDA-Antagonist Memantine. Unfortunately, the experiment was a failure and only side-effects from Memantine, in addition to withdrawal symptoms were felt.
Several other experiments were conducted with Intramuscular Ketamine and various other agents, from Dextro-methorphan to Mitragyna Speciosa (Kratom). The results of these will be published here soon.
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SWIM has read of similar experiences with methamphetamine.