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#1
24-03-2008, 14:38
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Ketamine Analogue: 2-Methylamino-2-phenylcyclohexanone
Has anyswi ever made experience with that substance?
It is said, that the o-Cl group at the Phenyl ring is somehow responsible for the dissociative effects of ketamine. Otherwise, the 2-MeNH-2-PhCyclohexanone is said to be twice as potent as ketamine, even fourth as potent when the MeNH- is substituted by an EtNH-group. How does this potency show up then? Is there still dissociative activity, though the o-Cloro-group is missing? Or is there only an altering of narcotic effects? 
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