Injecting - I.V. cocaine = serious health problems in future?

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Are there any health problems that go beyond that of routine insufflation use of cocaine, that occur to IV users?

MINUS the obvious health concerns regarding needles and infections, and vein care.

Does cocaine administered directly into a bloodstream cause long term or short term damage other than whats typically found in snorting users?

hypothetical example given;

snorting cocaine for 5 years=increased chance of heart attack, blood pressure, perhaps brain damage...

injecting cocaine for 5 years=10x increased chance of heart attack, mental problems, very very high chance of blood pressure, etc