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Picamilon - Recreational Potential??
Has anyone ever used it, does it have potential for abuse? Nothing on Erowid, like usual...
wikipedia
Quote:
Picamilon is a compound formed by reacting niacin with GABA. It was invented in Russia.[1] Picamilon is able to cross the blood-brain barrier[2] and activate GABA receptors, producing an anxiolytic response.
Quote:
Neuropharmacological screening tests on Picamilon have demonstrated its tranquilizing properties in small doses. For instance, at a dose of l mg/kg, Picamilon prevents the negative consequences of emotional stress (in cats it normalizes the orienting reaction when disturbed by the response to rage and fear). Like diazepam, it has an inhibitory effect on motivated aggression, associated with fighting for territory in rats.
Quote:
Investigation of Picamilon's effect on the threshold of "self-stimulation" showed that in higher doses (80 and 160 mg/kg), in contrast with small doses which have a tranquilizing effect, Picamilon lowered the "self-stimulation" threshold (like amphetamine), but at the same time reduced the number of self-stimulation. The stimulating action of the drug also has been shown in general anesthesia. For instance, at a dose of 100 mg/kg, Picamilon reduced by 1.7 times the duration of the sedative effect of hexobarbital sodium and reduced by half the duration of thiopental anesthesia.
Apparently its considered a smart drug, its legal online, I'm not shure if they rock it at GNC.
Thoughts?
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