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Old 26-10-2007, 22:44
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Hypothesis: pyrrolidinopropiophenone analogues - are they the next BZP?

http://en.wikipedia.org/wiki/Alpha-p...opropiophenone

Are pyrrolidinopropiophenone analogues the next BZP/TFMPP party pill replacements? [Not mentioning any brands, more of a general question] What does anyone think?

SWIM would predict they could be used or might show up soon & replace the stimulant part of the party-pill formulations [?] Especially if a BAN on BZP falls in to place in the UK. There is even good reason why they might be being used already.

Quote:
R,S-3',4'-Methylenedioxy-alpha-pyrrolidinopropiophenone (MDPPP) is a new designer drug with assumed amphetamine-like effects, which has appeared on the illicit drug market. The aim of this study was to identify the MDPPP metabolites using solid-phase extraction, ethylation or acetylation as well as to develop a toxicological detection procedure in urine using solid-phase extraction, trimethylsilylation and GC-MS. Analysis of urine samples of rats treated with MDPPP revealed that MDPPP was completely metabolized by demethylenation of the methylenedioxy group followed by partial 3'-methylation of the resulting catechol, oxidative desamination to the corresponding diketo compounds and/or hydroxylation of the pyrrolidine ring with subsequent dehydrogenation to the corresponding lactam. The hydroxy groups were found to be partly conjugated. Based on these data, MDPPP could be detected in urine via its metabolites by full-scan GC-MS using mass chromatography for screening and library search for identification by comparison of the spectra with reference spectra.
http://www.amphetamines.com/mdppp/index.html

Reputation Comments on this post:
  
  interesting to hear speculation on the direction of the RC trade.

Last edited by Zaprenz; 27-10-2007 at 11:18.
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