Codeine+CYP3A4 Inhibitor

15-06-2007, 00:49

ironmics

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Join Date: 26-08-2006

Location: PNW

Age: 23

Posts: 293

Codeine+CYP3A4 Inhibitor

http://www.drugs-forum.com/forum/loc...=2199&catid=24
According to this report a man almost overdose on a small dose of codeine when his ultrarapid metabolism was combined with a 3A4 inhibitor! Grapefruit juice is a 3A4 inhibitor and barely any 2D6. Here is some scientific backup that grapefruit juice WILL potentiate codeine. The most promising was the amount of morphine-6-gluc he had in his system which was quite outrageous.

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