Would grapefruit juice make hydrocodone/alcohol combination more dangerous?

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Would grapefruit juice make hydrocodone/alcohol combination more dangerous?

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04-03-2007, 06:02

GForce

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Join Date: 25-11-2006

Location: United States

Age: 22

Posts: 395

Would grapefruit juice make hydrocodone/alcohol combination more dangerous?

SWIM was curious if drinking grapefruit juice in order to potentiate hydrocodone would make alcohol more dangerous. Apap and alcohol are both metabolized by the liver so he was worried that the inhibition could cause some kind of toxicity issue. He wasn't considering heaving drinking maybe just a beer or two.

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