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  #26  
Old 27-07-2009, 11:01
missparkles missparkles is offline
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Re: how much is a blocking dose of methadone?

Quote:
Originally Posted by Birkill View Post
Swims down to 21ml daily , well will be 18 as of today and the gear dosnt do half as much as it used to!!!
Just want to say well done...keep it going.
  #27  
Old 27-07-2009, 17:13
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Re: how much is a blocking dose of methadone?

swim hates it feel like shit every morning and i still pretty much relapse every other other day so cant wait til swim gets off the green stuff so at least the brown stuff hits the spot!!!!!!!!!!
  #28  
Old 27-07-2009, 17:27
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Re: how much is a blocking dose of methadone?

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Originally Posted by Birkill View Post
swim hates it feel like shit every morning and i still pretty much relapse every other other day so cant wait til swim gets off the green stuff so at least the brown stuff hits the spot!!!!!!!!!!
Swiy is coming of Methadone to go back on smack (heroin)? Considering how low swiy has managed to get on Methadone is that such a good idea?
Just asking?

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A very relevant question: why taper off methadone in order to resume heroin use?
  #29  
Old 27-07-2009, 21:32
east_of_eden east_of_eden is offline
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Re: how much is a blocking dose of methadone?

yes but if someone is using methadone and heroin and can't stop using both, it could be better (depending on the person's situation) to at least drop one of them so as not to have a double addiction.

sorry to be off topic, but swim says this ^^ because she knows how hard it is to get off methadone and it's easier to get off heroin if swiy wanted to down the line. (easier in regards to withdrawal period)

and if swiy is using both it kind of defeats the purpose anyways.

although saying that, swim is on both and it works for her. everyone's situation is different, but if swim ever did want to get off methadone, she'd do it by replacing it entirely with heroin and then coming off that.

east_of_eden added 4 Minutes and 15 Seconds later...

oh, and to answer the question, so swim isn't completely off topic, she thinks 30-40mg a day can be enough to be a blocking dose.

It will at least block it enough to where 1 and a half to two times the normal shot of heroin will be needed to feel it.

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good points

Last edited by east_of_eden; 27-07-2009 at 21:32. Reason: Automerged Doublepost
  #30  
Old 27-07-2009, 22:34
jmunny fo twunny jmunny fo twunny is offline
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Re: how much is a blocking dose of methadone?

woah! swiyour's is green? at swim's clinic it is red.

and yeah i'd have to agree with east of eden. herion is a cakewalk to come off of compared to methadone. in swims experience with heroin it takes about a week or 2 to come completely off it but swim came off methadone when swim took an unexpected trip to the clink and swim didnt feel normal again until almost 3 months later. uhh just thinking about it makes swim feel ill. ughh.
  #31  
Old 28-07-2009, 08:44
missparkles missparkles is offline
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Re: how much is a blocking dose of methadone?

Methadone Mixture can also be a clear liquid in it's concentrated form.
Swim read here at DF that swiy got a straw coloured liquid. Swim has had that too.
Methadone Linctus, (2mg/5mls) and is normally used to treat coughing in terminal illness.
Sorry for straying off topic.
  #32  
Old 28-07-2009, 14:14
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Re: how much is a blocking dose of methadone?

Personally swim finds that methadone begins its blocking effect at doses as low as 15mg/day.

He begins to notice a reduction in the rush and euphoria aspects of the heroin high from that dose upwards.
At doses above 30-40mls/day swim still gets a rush (from IV use), but experiences no euphoria.......just the nods.

Above 80mls/day and swim can hardly get anything of a 0.2-0.3g IV injection.

Swim really found a sudden flooding back of the euphoria when he got down to 15mls and below.
  #33  
Old 29-07-2009, 23:22
Helene Gold member Helene is offline
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Re: how much is a blocking dose of methadone?

SWIM would have to agree with mickey bee, it starts blocking as soon as you start taking it. And just because you haven't taken your dose for one day, the previous day's dose will still have a blocking affect on your hit.

Best not to double up, eh? Don't wanna find yerself with a habit bigger than necessary.

Anyhow, all you SWIMers out there know the best hit ever is the one you've had after you've been up all night rattling, ill as fuck, waiting for the morning to come, for your money to clear, to go out and score...that's the one that does it, that hits the spot...so it'd stand to reason, that any meth in yr system would work against it, wouldn't it?

H
  #34  
Old 13-08-2009, 00:04
deltakilo deltakilo is offline
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Re: how much is a blocking dose of methadone?

SWIM has had plenty a high while on 40mg of -done, but when using 60-70mg/day swim noticed a drastic difference in the amount of euphoria that was present when using oxy or dilly.
  #35  
Old 16-08-2009, 23:42
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Re: how much is a blocking dose of methadone?

About a year ago when SWIM was in his last methadone clinic, they were using the orange 40mg wafers for some people, but also had a machine that dispensed clear liquid for more accurate dosing. The orange wafers they'd dissolve in warm water (gross), and give you OJ to take with after. The clear stuff they'd mix with fruit punch which was also gross. It was $60 a week.

As for the blocking dose, SWIM has heard so many different things he doesn't know what to believe.
  #36  
Old 01-01-2010, 02:23
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Re: How long does methadone block other opiates?

Swim says:

Well, just for an example I have been on 100mg of Methadone for 4 months and I quit cold turkey.. I planned to use other opiates while the worst of the withdraws where hitting and Its been over 100 hours, about 4 1/2 days and I took about 200mgs of oxy with out feeling a thing!! So, I hope this gives you an idea and for my sake, I hope its starts to work soon because I am feeling the pain!!

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Last edited by Helene; 17-01-2010 at 13:09. Reason: self incrimination
  #37  
Old 01-01-2010, 12:52
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Re: How long does methadone block other opiates?

Quote:
Originally Posted by FlyByNight View Post
Well, just for an example I have been on 100mg of Methadone for 4 months and I quit cold turkey.. I planned to use other opiates while the worst of the withdraws where hitting and Its been over 100 hours, about 4 1/2 days and I took about 200mgs of oxy with out feeling a thing!! So, I hope this gives you an idea and for my sake, I hope its starts to work soon because I am feeling the pain!!
That is very strange? SWIM usually takes anywhere from 40-120mg daily and can usually feel other opiates just fine after 12 hours. To *really* feel the effects he just waits 24 hours..

Granted some people metabolize methadone WAY differently than others (ie: for some half-life is <24hrs while others is 72hrs). Peak plasma levels vary greatly with this drug from person to person. Still, 4.5 days ought to be *more* than enough time regardless of the amount consumed..

PS: please don't self incriminate!!
  #38  
Old 03-01-2010, 06:11
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Re: How long does methadone block other opiates?

swim takes 50-60mg of methadone a day and has for a few years...swim still buzzes of eating like 50-100mg of oxycodone. if swim takes 30 mg of oxy swim feels good. methadone just raised swims tolerance alot! everyone metabolizes the drug differently as said above. the doses in which methadone will start to BLOCK other opiates effects in swims opinion, again varies, but is 100mg on a daily basis for at least a week, or more obviously ). the tolerance increase was good/bad for swim, bc swim has to rail, smoke, eat like 2 80's to get even a bit high...3 really....and has to mix benzos to nod..but it also makes swim not want to abuse oxy, swim is content with the pain relief and slight buzz due to the fact methadone does help with urge at low doses to some extent, and when you have to do 3 80's to get high....where there spendy in your area. its herion or bust..and black tar is just too nasty, unclean high that, eats away peoples veins unbelievably quick compared to good white/tan dope.
  #39  
Old 12-01-2010, 00:37
mashed mashed is offline
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overcoming methadone blocking effect

swims friend is on 60mg methadone at the moment.
shes really craving an opiate buzz due to her depression playing hell with her at the moment.
she took no methadone friday,60mg saturday,30mg sunday,and 60mg today.
the only opiates she has at her disposle in 30mg codeine tablets and 10mg diyhydrcodone -no heroin
what type of dose would be needed to overcome the methadone?
also what dose does methadone start to "block"other opiates from working?
thanks

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  #40  
Old 12-01-2010, 00:41
chillinwill chillinwill is offline
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Re: overcoming methadone blocking effect

Please see these threads as I am sure they will help you find an answer.
how much is a blocking dose of methadone?
can u get high while on dolophine?
methadone

A lot of reports that Red Rock has read say that 70mg is the level at which methadone "blocks" any other opiates. Red Rock has heard reports from methadone blocking people from using heroin as low as 40mg-80mg. Methadone doesn't block like buprenorphine, but instead saturates the opiate receptor sites enough that no other opiate can get through. As far the doses to overcome this effect with dihydrocodone or codeine, I would assume it is a fairly significant number as methadone does a fairly decent job of saturating the receptor sites making other opiate use almost impossible without increasing the normal dose exponentially.

Last edited by chillinwill; 12-01-2010 at 00:49.
  #41  
Old 12-01-2010, 00:43
johnnyyen johnnyyen is offline
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Re: overcoming methadone blocking effect

@mashed..considering your last post the last thing swiy want to be doing is more pills!! get checked out now!!
  #42  
Old 17-01-2010, 05:58
ToP-NoTcH ToP-NoTcH is offline
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Re: How long does methadone block other opiates?

Swim has been on methadone since July. Swim just had a 7 day hospital visit & found out swim has chronic pancreatitis. So swims dr said fuck the methadone and put swim back on oxycodone 20's,dilaudid 4's & percacets 5/325. Swim only feels the dilaudid's. Swims tolerance from taking 85 mgs of methadone for six months is beyond hi. While on the methadone swim could not get hi off of anything but dilaudids IV'd. So we are all different when it comes to tolerances. Swim has been off methadone since the 7th of this month and can still only feel the hi of 4mg+ of dilaudid IV'd.
  #43  
Old 22-08-2012, 18:22
kborodinski kborodinski is offline
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Re: Does methadone block out a bit of a hit of heroin?

Quote:
Originally Posted by CrookedEye View Post
The way methadone works is, when someone takes their first dose, it goes into the body and begins to fill one's organs, then on the next day of taking the same dose, it finishes filling up the organs and begins to raise one's blood levels. Then, on the third day of taking the same dose, it raises the blood level to the max for that dose, which can be effected by metabolism, etc..

This long acting opioid then maintains an endorphin level, so that if the same dose is taken each day, one's endorphins do not drop to the point of being sick.. When one is stabilized at a proper dose for treatment of addiction, which can vary widely from person to person, depending on their tolerance and metabolism, among other things, then they can often skip a day, without really noticing any withdrawal. The methadone stays in the receptors longer than any short acting opioid, so this causes any short acting opiate transmitters to not bind to the sites, resulting in a decreased or even no feeling at all.

If one desires to use methadone as a supplement, and wishes to remain able to use shorter acting opiates and experience effects, they should keep their methadone dose low enough to keep from getting really sick, but not high enough to notice no withdrawal symptoms, as this is the point where many receptors are full, but not all of them. The shorter acting, more euphoric opiate transmitters can bind to unfilled sites..

As stated above, this dose can vary widely from person to person depending on multiple factors, but for SWIM, when he was beginning methadone, he stopped noticing as strong effects from heroin, at around the 50-60mg level, and by 80mgs a day, he could no longer feel any of what his usual dose of heroin would normally do. At about 40mgs, SWIM wasn't totally comfortable, but noticed that when he used heorin, the effects seemed stronger when mixed with the methadone, than a proper dose of heroin alone..

Hope this helps..
I'm on 75mg of methadone right now daily. Tried to smash 1-2points of H and all I got was a 5% of the rush and then damn all!! How low on methadone you have to be to get off from H?
  #44  
Old 16-09-2012, 23:37
Staley36 Staley36 is offline
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Re: [b]Does methadone block out abit of a hit of heroin??[/b]

Quote:
Originally Posted by Junkhead23 View Post
That is why then try and get your methadone put down otherwise SWIY have to take large amounts to get an effect like SWIM
It's "but we are an elite race of our own...the stoners,junkies and freaks...are you happy?I am man..content and fully aware..money status?nothin to me...cause your life's empty and bare". For someone whose username is the name of the song,junkhead,seems like you would atleast know the right lyrics. Lol.

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  #45  
Old 13-10-2012, 21:24
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Re: how much is a blocking dose of methadone?

Quote:
Originally Posted by jmunny fo twunny View Post
i am sorry if this has already been answered, i searched the forum and couldnt find anything but i have been told that methadone does not block your opioid receptors yet some people say it does. swim goes to the methadone clinic everyday and is up to 140mg and has noticed that large amounts of herion used interveniously (.5g in one shot) does not have any effect on them at all. where as the same amount would get swim to a nice warm place but now they dont even get a rush... and someone at the same clinic is on 180mg and claims that they still get high off a smaller amount of diesel. i know everyones body is different, it just doesnt make sense to me. could anyone help swim out?
if your methadone dose is 70mg (or is it 80?) and higher, it'll block any other opiates. so even if you do a shitload of heroin, you won't feel it but it will still be in your system and could cause an overdose. a lot of people make that mistake. they're on a high dose of methadone, can't feel anything anymore so shoot up some dope, still don't feel anything so shoot some more and more and more and you never end up feeling anything but you get very close to overdosing because there's such a high amount of opiates in your body. be careful with heroin on high doses of methadone.
  #46  
Old 14-10-2012, 21:10
kborodinski kborodinski is offline
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Re: How long does methadone block other opiates?

I'm down to 65mg of methadone. I don't exactly know how low I should go to feel any of the smack at all. I know a guy who used the same smack and got off. He is on 120mg of methadone. I don't get it?
  #47  
Old 24-03-2013, 12:33
chopmow chopmow is offline
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Re: How long does methadone block other opiates?

no one has answered the op question after all this time and all these posts.

surely someone has been through this?

anyway...............

normally my friend takes 70mg everyday, which totally blocks all effects of heroin for me.

he's been off the methadone for 8 days and still cannot feel the heroin, shooting 200mg of pure dope 3 times or more a day and all it's doing is stopping wd and making him tired sometimes.

wonder if day 9 will see the heroin euphoric for him? or day 10?

does anyone have any expericance?

speak up
  #48  
Old 26-03-2013, 00:38
chopmow chopmow is offline
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Re: How long does methadone block other opiates?

day 9 nothing................

day 10.........he just did a shot, maybe something small, could just as well be placebo though.
  #49  
Old 22-05-2013, 11:09
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Re: How long does methadone block other opiates?

im on methadone maintenance and i shot h for over a year daily. it somewhat blocks it but if u do enough u can feel it not strong n good like first thou obv. u will b fine doing Vicodin but done is way stronger id wait til u feel it.
  #50  
Old 22-05-2013, 12:07
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Re: How long does methadone block other opiates?

hmmm,it seems the opposite for my friend? they've came down from 95ms daily of methadone to 6mls daily (weaning off slowely)
my friend noticed even on the 6ml,taking quite a few pills of codeine,they thought it would defo effect them with being on such a low dose,but absolutely nothing no effects what so ever?

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blocking doses, blocking doses of methadone, methadone and heroin, methadone blocking dose, methadone clinic, methadone dose, opiate

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