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  #1  
Old 22-11-2011, 21:54
eggs eggs is offline
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how long after taking sub can i take methadone?

i took 2mg of sub about 5 hours ago and i still don't feel all that great.


i now have 100 mg of methadone, can taking it too soon (5 or 6 hours) after the sub still risk precipitated withdrawals?

eggs added 1 Minutes and 37 Seconds later...

just to add more info, this was the first time i've taken a sub in about two months, it usually takes about 4mg to make me feel okay and i only took two, and my last opiate dose was about 30 hours before that if that matters.

Last edited by eggs; 22-11-2011 at 21:54. Reason: Automerged Doublepost
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Old 22-11-2011, 22:55
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Re: how long after taking sub can i take methadone?

Hi there,
Taking the methadone after the subbie won't put you into precipitated withdrawals - bupe has a stronger affinity for the receptors which means it binds tighter than the methadone will...so what is more likely is that you won't feel the methadone because the bupe is blocking it.
Bupe has a very long half life...37 hrs....but on saying that, some people are able to use opiates with low levels of bupe and still 'feel' it.
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Old 22-11-2011, 22:59
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Re: how long after taking sub can i take methadone?

Thank you kindly

Btw..just out of curiosity i know taking bupe after methadone woud cause WD
and i guess taking methadone shortly after bupe is safe ( though maybe inneffective

What would happen if you took them both at the same time? ( im not going to try this..just curious about how they would interact in theory)
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Old 22-11-2011, 23:09
catseye Gold member catseye is offline
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Re: how long after taking sub can i take methadone?

that's an interesting question, lol...the short answer is I have no idea! My best educated guess would be that the bupe would 'win' and would bind to the opiate receptors so tightly that the methadone would cause precip wd's.
They wouldn't cancel each other out I don't think - boy I'd hate to try
Good luck and post an update if you can, let us know how the methadone dosing goes and how you're feeling. Be well.
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Old 23-11-2011, 01:33
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Re: how long after taking sub can i take methadone?

Thanks again! I appriciate your help a lot

eggs added 133 Minutes and 54 Seconds later...

Just a quick update for anyone interested

Took about 50mg about 6 hrs after the sub..about 90 min aftee that im feelin good (prob not as good as i would if i didnt take the sub..but it was worth taking. I didnt waste it

I would have taken all 100 but i decided to save half for tomorrow

Last edited by eggs; 23-11-2011 at 01:33. Reason: Automerged Doublepost
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Old 23-11-2011, 03:36
Believf Believf is offline
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Re: how long after taking sub can i take methadone?

Just a quick note too. If you do take methadone or really any opiate you should wait at least 6 hrs before taking any sub. AFOAF was prescribed 16 mg of sub a day and they'd sometimes get impatient. There were times when taking any opioid too soon after made them feel not so great and only time helped. Your best bet, if you can, is to stick with the sub regularly if you're prescribed and maybe treat yourself once in a while. Otherwise everyday is a rollercoaster. And please don't do both at once, my ventriloquist dummy had trouble sleeping for days switching back and forth. Good luck.
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Old 23-11-2011, 03:53
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Re: how long after taking sub can i take methadone?

hey buddy.. thanks for the input, but i think you have misinterpreted the info here... taking subs (even 6 hours after) any opiate is very dangerous. i was asking about taking opiates after the subs.


also ps: i apologize for my bad spelling and grammer in previous posts, i was posting from my phone

Post Quality Evaluations:
correct information re: subs *after* opiates. good job

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buprenex, buprenorphine, dope, methadone, opiate, opioid, opioid addiction, opioid dependency, suboxone, subutex, temgesic

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