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  #1  
Old 23-08-2009, 16:56
el burgo el burgo is offline
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Quetiapine and Magic Mushrooms - Safe?

Is it safe to combine quetiapine and magic mushrooms ?????

Last edited by Phenoxide; 26-06-2011 at 23:12. Reason: clarification
  #2  
Old 23-08-2009, 19:23
Boca Bitch Boca Bitch is offline
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Re: Quetiapine and Magic Mushrooms - Safe?

Not an advisable combination again... quetiapine is likely to block out some of the effects of psilocin, while increasing the chance for adverse effects to develop. Danger is not nearly as high as in the other question regarding SSRIs, but it's still not likely to result in an enjoyable experience.
  #3  
Old 23-08-2009, 22:01
el burgo el burgo is offline
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Re: Quetiapine and Magic Mushrooms - Safe?

Boca Bitch just saved SWIMS ass
Thankfully swim did not find any mushrooms when he went picking today...and he does not plan to whilst on such meds.
cheers
  #4  
Old 26-06-2011, 20:44
natey7 natey7 is offline
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Re: Quetiapine and Magic Mushrooms - Safe?

SWIM had one of the craziest trips yesterday that Swim has ever had!

Swim couldn't figure out why it was so much crazier than the other trips that Swim's had in the past because he didn't even take a full eighth this time around!! And he's had WAY bigger dose trips in the past.

Swim really wasn't ready for it, but at the same time it was VERY eye opening and meaningful. And today the afterglows one of the best one's that Swim's ever been left with to boot!

Swim's not going to go into to much detail about the events that happened throughout the trip but man, there was tons of non-ego'd spirtually, intense conversations with another fellow travellor who was tripping with him. And later some other people that they met up with as well.. Tons of venting to, which afterwards made Swim feel so much better about stuff in general.. And even a little bit of crying to complete the venting process of all the shit that Swim's been going through in his life(which is another story).. But at the same time it felt awesome for Swim, and the hallucinations were out of this world!

At one point Swim actually thought he had died and went to heaven with the fellow tripper and friends that were around at the time. He actually thought everything was all over and it really made swims mind feel like all of the shit that's been happening was done with/completed.. Every shitty thing in life didn't matter anymore to Swim.

Swim would say the closest comparrison to the feeling it left him is in a way the same that Opiates used to make Swim feel back in the day when he still used them. Swim was left in a space of nothingness but wasn't even on any opiates! Swim felt the togetherness of him before all the problems took hold.

In fact Swim was getting so comfortable around these people that for some reason Swim thought that he had to take of his clothes(Adam and Eve crossed his mind at the time), and he eventually started to take off his socks and than his shirt. When it got to the pants Swim felt pretty pissed that he had to take off his pants in front of all these people but luckily didn't have to!.. He suddenyl realized that he wasn't dead and they actually do still need clothes :P. Plus he realized that these people are gonna freak the fuck out if Swim takes off any more clothing! So Swim quickly put his clothing back on and continued with the trip.. At the time it was very embarissing for Swim.

Swim felt like Swim was getting super warm as well, kinda like an opiate used to make him feel. So that was another part that contibuted to Swim thinking everyone was suposed to roam around naked and free.

Don't ask, it was really messed up. And Swim had to laugh about it a little this morning.

It was almost a feeling that he had when he was still a child with no worries or cares really. And it made swim realize how much easier swim has to try and be on himself in life. These problems are chewing Swim up inside already, and Swim realized he doesn't have to be even harder on himself about them and make things even worse than they already are. Especially with Swim being a recovering Opiate addict.. Swim's been making himself even more stressed than he has to be and stress is never a good thing.

All in all, Swim's happy it happened but Swim doesn't feel a desire to repeat the same accidental combination again(if that is what cause such intensity). It was intense enough, and if Swim wasn't already a very experienced tripper he would have freaked the **** out.

Nehow, it finally hit Swim what made it so crazy compared to all his other previous trips..

The night before, Swim was out of his usual sleeping pills(Melatonin), so Swims mom gave him a small dose of Quetiapine. It's good for sleeping at low doses and Swim had some left over from when a Doctor tried putting him on them after a breakdown. Eventually though, Swim realized he would be better off without them and really didn't need the medication so he quit it cold-turkey and hasn't looked back since. Things have been A LOT better without the medication as well.. It was such a waste of money, and Swim thinks that's one of the reasons the doctor was trying to keep Swim on it to.

Swim really thinks this mite have been what made such a big difference in the intensity of the trip.

It was making Swim think of the way an MAOI is said to make a mushroom trip or LSD trip a couple times stronger than it usually is. Or how it's used in Ayahuasca to make it work how it does and let the DMT take the right effect for a long amount of time.

Swim's not gauranteeing that this was why it was so intense, but Swim thinks this might have had something to do with it. Afterall no other trips have ever been like that one and Swim didn't even take that much Mushrooms!

The trip kinda reminded Swim of the time he smoked DMT. That's how damn intense it was at points. Especially in the beginning.. It was weird because Swim was tripping mass balls in less than an hour! It was a way faster come-up than it usually is, and it seemed to last forever to!

Caution: Swim would not recomend this combo to anyone who's not experienced at tripping.

Swim did benefit from it in his own kinda weird enlightening way, but it was verry intense.

Swim thinks one shouldn't attempt unless they are very sure they know what they're doing and are very experienced at tripping already. *Use caution just in case it was the Quetiapine.

If Swim would have tripped this one alone like he usually does with his Mushrooms, Swim doesn't think he would have been able to handle it at all.

It was a bonding experience, and Swim was also extremely empathetic like Swim would become on MDMA.

And to clarify, Swim's not saying this combo will make you cry or fuck with your emotions either. It may have for Swim at points, but everyone reacts with stuff differently.

Swim had some issues that he had to deal with from before that were stuck inside him for a while. The spiritual adventure of a trip really helped let everything out.

Swim can't imagine how it would be if the two were takin at the exact same time. Swim would suspect if one were to take a high enough dose of Quetiapine you'd probably pass right out within the hour and snooze right through your trip. Who knows, you might even have a crazier trip in your dreams.

When Swim used to take it to help him sleep during his opiate withdrawals it usually would pass him right out, even through that!(If enough is taken and it's taken at the right time that is). It also passes a person out through Marijuana withdrawals(insomnia). It is a lot stronger than any sleeping pill that you can buy OTC. And there's been times where Swim has felt like if he fell alseep on it he wouldn't wake up again because of how deep of a state in can put you in. Especially if you take to much.

Please be safe and use caution, just in case this is what made Swim trip so hard.

Last edited by natey7; 22-09-2011 at 16:18.
  #5  
Old 26-06-2011, 23:06
Crazy Insane Sanity Gold member Crazy Insane Sanity is offline
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Re: Quetiapine and Magic Mushrooms - Safe?

Sorry, Natey7, but I highly doubt the quetiapine had anything to do with the intensity of his trip. Quetiapine is a 5-ht2a antagonist. This is the main receptor that mediates the effects of psychedelics, and blocking it will negate those effects.

The lunatic has been on this drug for a few years, and he loves to trip on various psychedelics, but he has to completely clean out his system of the quetiapine before he does, or else he will get hardly any effects at all. It's nearly impossible to take a psychedelic and quatiapine together...in fact, quetiapine is often used as an emergency trip ender by some people.

The lunatic hasn't even noticed any intensification of his trips from cleaning out his system and tripping, or when he's only taking smaller doses either. The only effect it has ever had on his trips is negating it, and he has never heard of anyone having these effects before. I suspect that either the shrooms this person ate were more potent than he had expected, or that there is some other factor at play here. Intensity of trips can also vary, even within the same batch (likely has to do with set and setting, or variations in the potency of particular shrooms in the batch). I'm not saying that you or Swim are liars or anything...I just think he's mistaken in regards to why his trip was so intense.

Also, when you post, could you please insert more line breaks and paragraphs. It makes it a lot easier for other people to read, and it will help you organize your thoughts better.

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accurate reply backed up by experience
  #6  
Old 20-09-2011, 15:49
natey7 natey7 is offline
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Re: Quetiapine and Magic Mushrooms - Safe?

Sorry if Swim did not type his experience out well enough for you to read Crazy Insane Sanity. When Swim wrote it he was still a mass pot head didn't have the best writing skills. However today, Swim hasn't smoked pot in over two months and things have changed quite a bit for Swim .

Next time he will remember to type it out better for all the Swimmers out there.. And thanks for reminding me!

However Swim isn't saying that it absolutely does change the trip and will for others.

But Swim has tripped mushrooms MANY MANY times in the past and Swim has NEVER experienced such intensity during a trip like he did then when taking the mushrooms the day after using the Quetiapine to fall asleep. When Swim says many many times, he means at least 100 times already.

Swim kinda doubts it was just the mushrooms because it wasn't even that strong of a dose and Swim has had much stronger dose trips in the past. Plus the other Swimmer tripping with him didn't experience such intensity and had the same dose..

If one does decide to try the combo or takes some Quetiapine the night before, Swim would suggest using caution just in case it does effect the trip like it seemed to for Swim and maybe not taking too much mushrooms.

Swim had more of the same mushrooms left over after and had another trip with them later on during the month and the trip was nowhere near the intensity and craziness that this one was for Swim.

For the trips after Swim didn't have any Quetiapine whatsoever and hasn't dared to touch the substance since.

Swim usually buys his mushrooms in bulk so he had quite a few trips off of the batch and none of them compared whatsoever.

Swim would say it was so crazy that Swim almost didn't enjoy it.

The only time Swims mushrooms have been intensified like that was when Swim mixed DXM and mushrooms in the past and even that trip was a different kind of intensity.

However, like you said it might not have been the Quetiapine at all. After all Swim did eat only mushroom caps for that crazy trip.

But damn, whatever it was those were some STRONG mushrooms!!

Note: There's a possibility that it also could have been the people Swim was around while tripping that effected his trip. It really was a trip like no other.

Also, who knows what effects the combination could have, especially if one doesn't actually need to take the Seroquel, then I'm sure the effects could be different than they are for someone who actually needs the medication.. Who knows. Not everyone's brain chemistry are alike.

Last edited by natey7; 22-09-2011 at 16:27.
  #7  
Old 20-09-2011, 18:24
kailey_elise Gold member kailey_elise is offline
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Re: Quetiapine and Magic Mushrooms - Safe?

Quote:
Originally Posted by natey7 View Post
Sorry if Swim did not write his experience out well enough for you to read Crazy Insane Sanity.
It wasn't badly written or anything, it just could do with some more line breaks. More of them & use 2 of them between paragraphs to better separate them.
Quote:
Originally Posted by natey7 View Post
Swim had more of the same mushrooms left over after and had another trip with them later on during the month and the trip was no where near the intensity and craziness for Swim. Swim usually buys his mushrooms in bulk...After all Swim did eat only mushroom caps for that crazy trip. But damn, whatever it was those were some STRONG mushrooms!!
It's for that reason that many people like to grind their (dried!) mushrooms up & dose from there; that way you're more likely to have similar experiences each time out of that batch. I like to whizz my in a coffee grinder; not too much or for too long (minimizing 'trauma' & potential degradation), but it really only takes a few pulses of the blades to "homogenize" the caps & stems together anyway. This also can help with dosing, as then you can decide to take, say, 2 tablespoons per session or whatever.

However, as has been mentioned, set & setting have a HUGE impact on one's experience - even with the same amount from the same batch!

I know there was mention that (potentially) having Seroquel in one's system could be the reason for the intensification of the experience, and perhaps this may be true. However, what CIS (& I) are trying to say is...if that is so, that the person mentioned is a very very strange anomaly indeed, as Seroquel (quetiapine) is well known to PREVENT people from experiencing effects when taking 'magic mushrooms'. So much so, that people have taken it while having an experience they feel is too intense, to ABORT the trip.

So in general, it would NOT be recommended to take Seroquel if one plans to have an experience with magic mushrooms.

~Kailey

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good reply on potential of quetiapine to prevent tripping
  #8  
Old 20-09-2011, 20:15
Crazy Insane Sanity Gold member Crazy Insane Sanity is offline
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Re: Quetiapine and Magic Mushrooms - Safe?

Kailey_Elise pretty much summed up what I wanted to say, but I'll go ahead and say it anyway.

I may have been a bit too dismissive, but I wasn't trying to say it's impossible that the quetiapine somehow intensified the effects. I just find if very unlikely. Perhaps it did somehow intensified that person's experience, and I'm just not aware of what mechanism it would have done so by.

However, given quetiapine's antagonistic properties at the 5-ht2a receptor, it should block the effects of psychedelics, not intensify them. This can be backed up by numerous anecdotal reports, and seems to correspond with it's mode of action. If it did somehow intensify the experience, I would find this very interesting. I just think that it is much more likely that there were other variables at play in this situation.

Also, as Kailey_Elise noted, I didn't find the wording of your post difficult to read at all. It was the fact that it was all just sort of jumbled together. By separating posts into paragraphs, with line breaks between them, it makes it a lot easier to read.
  #9  
Old 20-09-2011, 22:17
natey7 natey7 is offline
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Re: Quetiapine and Magic Mushrooms - Safe?

Thanks for the heads up Kailey and Crazy Insane Sanity. Swim never even thought of using two of them between paragraphs, so that is some very good input!

And yes, Swim would have to agree. Grinding them up is a very good idea when tripping. Sometimes Swim does that when he makes tea out of the shrooms. And sometimes even just using scissors like one would to grind up their marijuana works very well for Swims mushroom tea as well.

However, Swim has found that when grinding his mushrooms up and re-weighing the weight afterwards, the weight never seemed to change for Swim whenever he has done this in the past. Swim has had his mushroom trips in many different forms before.

But to each their own.

Swim loves drinking it out of tea but for this trip Swim and his fellow tripper were so excited to trip that they both just shoved the mushrooms in their mouth and had at er!

Swim used a scale for this trip(which Swim always does for his trips). So Swim would think the dose should have been pretty accurate at the time..

Swim has also read from somehwere that Seroquel can reduce the effects of ampthetamines like meth or even cocaines effects.

Although, Swim is not so sure how Seroquels effects would be if one were to take it while already through most of their Mushroom trip to try and abort it or even calm themselves down. Swim thinks it might even just pass them out if they were to do that because he finds it was always a VERY strong sedative for Swim in the past, even at really low doses(which might even be of help if they really wanted to end the trip). Some say that Seroquel works a bit for anxiety to, so Swim could see how it could help someone calm down.

For Swim it was taken the night before so Swim is really not sure how it would be if someone took the two at the same time or the Seroquel a little before the trip on the same day.

Swim would be interested in hearing someone's experience more on the two. And in which way they were taken and if it had any effects like Swim found it to on that day. Or even just hearing what effects it had on their trip in general. As well as the difference in taking it after the trip or near the end, during the trip, the day before the trip, or even on the same day but before the trip etc..

However, Swim kinda doubts that there are that much people who have tried the combination. It is a weird combination and Swim only did his by accident.

It would still be very interesting to Swim though.

Whatever the case may be, it sure didn't reduce Swims trip whatsoever. If anything he thinks it made it even crazier.

But then again everyone gets affected differently. And every individual is unique in their own way.

All Swim was really getting at is to use caution if doing what Swim did. Just in case one were to find the same thing happen to them that happened to Swim.

But hey, when tripping it's always a good idea to use caution and be as safe as possible .

And you were right, it does look better with the extra space in-between. Thanks!

Happy & safe trippin everybody!

Last edited by natey7; 22-09-2011 at 16:39.

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antipsychotic, cocaine, magic mushroom, magic mushrooms, mushrooms, opiates, quetiapine, quetiapine combinations, quetiapine interactions, seroquel, shrooms, ssri, tripping

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