Opinions - What Dose?

[On The Nod]

If someone has acces to daily morphine what dose would be best to use(IV) every day and keep SWIM feeling comfotable, with Heroin users people report to feel happy on between 400mg-1gram daily and they dont need to increase from here...

However whats the score with Missy M... SWIM could have 200mg iv and not even feel anything which is a little dissapointing, however would a higher dose keep him sweet for ever?.. or.. Would he need to keep increasing forever?... Anyone got any experiences??

[Dickon]

My cat asked me to pass on the following message to you....

First of all, people reading this should note the doses mentioned are very high, and could easily kill an opiate-naive person. If such a person is tempted to i.v. morphine, a more realistic dose would be 10mg, but sensible advice would be to start even smaller, just in case you have a bad reaction.

Clearly "On the Nod" has considerable experience with opiates. The name suggests such, but I think you are labouring under an illusion. The happiest period of my opiate use was when I was taking 40-60mg morphine orally once a day. I managed for a while to maintain a fairly steady daily use with few problems (at least as far as being an opiate addict is concerned) but things did spiral out of control. Although I never injected morphine, I did inject heroin and methadone, and my highest dose of oral morphine was 4,500mg in one day (2,500 then 2,000 a little later). It had a negligible effect, but I was taking at least 200mg methadone a day. Even when I injected 700mg methadone it was never enough.

I just don't believe there's a suitably high dose at which you'll be able to experience a consistent happy life on opiates. High doses of opiates that blockade the receptors provide an overall "greyness" to existence. They only work euphorically when there is a sudded rapid change of level, and the receptors aren't constantly stuffed with opiates.

That you are injecting 200mg morphine without effect proves to me you're advancing up the ladder of tolerance. Yep, you might get a buzz for a while with 300 or 400 or however much. When that becomes the norm you'll likely want more, if it's available. There is no way to be constantly happy on opiates. If all the receptors are full the body will just make more that will need to be filled!

Upping the dose is a losing game. It's what we pretty much all do. Nowadays, I'm just glad I'm off the stuff altogether, and get my opiate buzz from endorphins!

Dickon