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GHB GHB, GBL and related psychoactive substances

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Old 26-10-2008, 18:56
marcobrien marcobrien is offline
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Gbl dose and effects

My friend decided to try GBL after reading about it on this forum, so purchased some from UK website. When it arrived, the container was marked GBL 99.90%.

Following instructions from other forum members, he initially took 1.5ml diluted with cold water. He had eaten about an hour before. After about an hour he still had not felt anything, so took another 1ml dose with Coca Cola. Again, still no effects were felt.

My friend weighs about 15 stone & has used most recreational drugs during his life.

As a noobie, I would really appreciate any help & advice other members can offer so that I can pass on to my friend.

Thanks
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Old 27-10-2008, 10:53
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Re: Gbl dose and effects

GBL is rapidly converted into GHB by lactonase enzymes found in the blood. GBL is more lipophilic (fat soluble) than GHB, and so is absorbed faster and has higher bioavailability; the paradox is that this can mean that GBL has a faster onset of effects than GHB itself, even though it is a prodrug. The levels of lactonase enzyme can vary between individuals, and GBL is not active in its own right, so people who have never tried GBL before may have delayed or fewer effects than expected; however, once someone has taken GBL a few times, the production of lactonase enzymes is increased and he/she will feel the effects like normal.

Last edited by MrG; 29-10-2009 at 09:50.
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