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Old 11-04-2008, 22:08
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Aspirine Poisoning

This thread is supposed to be about infos & experiences with Aspirine poisoning. To avoid this, one should always consider a Cold-Water-Extraction: CWE FAQ: Links, Lists & Manuals !

I can, again, just stress the need to go to the hospital, if one feels sick! Don't play with your help, these steps here described are rather used for prevention than treatment. Self-treatment is not an option if you feel seriously sick or if you OD'd!!!!
I guess its always a good decision to have a healthy nutrition and take longer breaks between usage. Also drinking water is always adviced. Further information needed.

I'll start with a short summary:

Therapy:

There is no antidote to salicylate poisoning. Frequent blood work is performed to check metabolic, salicylate, and blood sugar levels; arterial blood gas assessments are performed to test for respiratory alkalosis and metabolic acidosis. Patients are monitored and often treated according to their individual symptoms, patients may be given intravenous potassium chloride to counteract hypokalemia, glucose to restore blood sugar levels, benzodiazepines for any seizure activity, fluids for dehydration, and importantly sodium bicarbonate to restore the blood's sensitive pH balance. Sodium bicarbonate also has the effect of increasing the pH of urine, which in turn increases the elimination of salicylate. Additionally, hemodialysis can be implemented to enhance the removal of salicylate from the blood. Hemodialysis is usually used in severely poisoned patients; for example, patients with significantly high salicylate blood levels, significant neurotoxicity (agitation, coma, convulsions), renal failure, pulmonary edema, or cardiovascular instability are hemodialyzed. Hemodialysis also has the advantage of restoring electrolyte and acid-base abnormalities; hemodialysis is often life-saving in severely ill patients.

All overdose patients should be conveyed to hospital for assessment immediately. Initial treatment of an acute overdose includes gastric decontamination. This is achieved by administering activated charcoal which adsorbs the aspirin in the gastrointestinal tract. Stomach pumps are no longer routinely used in the treatment of poisonings but are sometimes considered if the patient has ingested a potentially lethal amount less than 1 hour previously. Repeated doses of charcoal have been proposed to be beneficial in aspirin overdose. A study performed found that repeat dose charcoal might not be of significant value. However, most toxicologists will administer additional charcoal if serum salicylate levels are increasing.

Edit: apparently Capsaicin (in chili plants) is supposed to be a mild antibiotic but also having properties of lowerin side-effekts of asprine.. Thats what SWIM heard, no source about that, further info would be nice.

Last edited by 0utrider; 12-07-2008 at 17:47.
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