extreme sensitivity to adderall (and other stimulants)

[paperstreet]

How is it possible that swim has taken a 10 mg adderall XR at 10am (along with another 10 mg of regular adderall at 3 pm) and is still feeling the effects 17 hours (its like 3:30 am here now...) after initially taking the dose? Swim was extremely tired and hungover this morning right before taking the mere 10 mg on top of that, and still he has not eaten hardly anything all day. Swim also drank a lot of caffeine but that was at 11 am till 3pm, not a drop since.

This also happens after swim takes a 36 mg of concerta. Swim will not be able to sleep for about 2 days no matter how fatigued he feels.

These amounts seem miniscule but for some reason stimulants last FOREVER for swim. This sounds like a good thing but swim really needs some sleep especially after taking stims.

Swim normally has trouble sleeping, but this is rediculous... swim feels like the adderall is going to keep him up for a long time to come and is very frustrated...

[jazzmetalguitar]

well...typical length of effects for adderall are 10-13 hours. however, i have certainly had friends who have effects last up into the 20 hour range. it seems nothing more to me than the fact that everyone's metabolism and bodies are different and thus not everything will react the same.

as far as the caffeine goes. sure, its just caffeine, but you are already on a fairly powerful psychostimulant (albeit not so high a dose). you should avoid all other stimulants while on adderall if you don't have ADD or ADHD (as both dextro-/levo-amphetamine salts cause opposite effects of "adderall speeding" in people who it is actually made for).

now. the concerta, when did you take this exactly? and do you take any other medicines? i am on beta-blockers (propanolol, specifically) for essential tremor and in me i've noticed it counter-indicates strongly with methylphenidate and to some degree with amphetamine salts.

just need more details?

[mitch88]

Certain people have biochemical makeups that are predisposed towards ultrasensitivty towards the amphetamine family, just as genetic factors can exist for increased likelihood of opiate tolerance/ultrasensitivity (yes, even enzyme-oddities aside.)
SWIY could very well be one of those lucky ones.

[SummerLove]

where d0 y0 get adderall

[mitch88]

Originally Posted by SummerLove

where d0 y0 get adderall

Only from doctors and for legitimate, prescribed use, of course.

[paperstreet]

Mr. mitch please tell me more about the biochemcial makeups of those who are ultrasensitive to these certain things, if you can someone who is NOT me would appreciate it.

As for the concerta, im sorry for the long delay in posting jazz, but there really isn't much else to say, a 36mg concerta will keep swim awake but not "focused" (except the first 12 hours) for days on end... it sounds good but ultimately will destroy SWIM. No other drugs are taken by swim besides the occasional bowl pack and line of coke blah blah.... nothing to regular that would really interfere with the absorbtion of amphetamines.......

SWIM took half of a cotton of propylhexedrine (benzedrex inhaler) yesterday and could not fall asleep until 8am, when the propylhexedrine was taken at 12:30pm the previous day... swim was active until about 3 oclock..., but the final 5 hours were spent lying awake and very bored in bed... the few hours of sleep were not even that great sadly, but still swim was thankful for the rest...

[mitch88]

Well, let me put it simply: (as science and definitely myself don't have a full grasp on the exact why's and how's)
But people generally geared towards the poles of activity level (the depressed, or the manic/anxious) rarely experience the releases of dopamine and norepinephrine at significantly higher levels than the average subject. This not only means higher "highs" but also can mean dramatically extended ones, as the drug reaches its half-lives, one's brain still responds to the miniscule amounts left circulating (whereas others receiving this same small dose would perceive an end of the effects at that point.)