Drug info - ALD-52 vs. LSD-25

[Mortarhate]

Aye, I was wondering if anyone could help me out on this, I'm sorry if
my question seems stupid but I can't seem to find any good resources on
Organic chemistry, and I don't know how the damn carbon rings are
numbered (neither do my chem teachers lol).



ALD-52 differs from LSD-25 in that at N-1 there is a COCH3 connected to
the pyrrole ring as apposed to a single Hydrogen (found in LSD-25).






This is fine but by definition the
pyrrole ring is a heterocyclic ring of C4H5N, and the only Hydrogen
connected at a Nitrogen is near the bottom (of the picture). But that
is not a pyrolle ring. Supposedly the double bonds between the carbons
act as a Hydrogen but that would only make up 4 if my math is right.
Meaning C4H4N. How would that be possible? Is that were theCOCH3 connects?

Im not sure if I should even bother with it. Some people say ALD-52 is
better than LSD but others disagree. I havent had the pleasure to
synthesis or try either

[Labrat]

ALD-52 is simply 1-acetyl LSD. A acetylgroup is placed on the indolic nitrogen by reacting LSD with a acylating agent. This acylating agent could be acetic anhydride, acetyl chloride or ketene for example. Forgetthe idea ofever being able to isolate and keep pure ALD-52 since some of it will break down to LSD and acetic acid. This can't be avoided under conditions outside a lab.


There is no pyrrole ring in LSD but there is a indole.

[Mortarhate]

i appologize for the assumption. i've heard in many documents that the
carbon ring in the bottom of the picture was a pyrrole. so the indole
ring is the one on the bottom of the picture.

another thing. would it be useful to try synthesis if i kept product
under freezing temperatures. I still hear ald-52's affects are more
pleasurable than lsd's.

[Labrat]

No need to appologise. But check up some chem literature so you can see the difference between the various ring systems. I would have given you some links if a I had any. You can't compare pyrrole with the pyrrole-like ring present in LSD since it is a part of a indole system.


You will not be able to synthesise ALD-52 without contaminate it with LSD. If the techniques needed were available to you you would not have to ask these questions. Let me make a wild guess; the vast majority of people claiming to have experienced the effects of ALD-52 have no clue what so ever what they actually consumed since they had no possibility to analyze the drug. Most of them are just flapping their lips about things they don't know anything about. Sad but true.





/Merry Christmas

[Mortarhate]

hah, I'll have to keep that in mind. So synthesis of lsd-25 should be
sufficient. do you know of any good books on organic chemistry maybe?
I'm sure a book like that would cover many ring structures.

Im glad, though, that you say that, because synthesis of ALD-52 comes
from what I can see undocumented, and I dont think I even posses the
skill to synthesize it's parent, LSD.