Just finished most of this book. I read about 2/3 because I wasn't all that interested in the info about using MDMA to treat schizophrenia, PTSD and depression. Well not in reading the whole chapters anyway. That had all been touched on earlier in the book.
It really is a very well researched book. I have respect to the author. As well as the enormous amount of research and studies and experiences shared in this book there are some good ideas/insights. Not anything new really, but it's well presented in terms of the goal the author was pursuing and arguing for (and against prohibition and the ridiculous fervor which drugs tend to get caught up in). She has sound medical arguments and it all sounds like it could convince most sensible people who are willing to listen. But there is a bit of stuff on spirituality and such that isn't so convincing to skeptics. Anyways, I thoroughly enjoyed the bits that I read and would recommend this to those with an interest in a good history of MDMA as well as it's seemingly vast medical potential. It covers harm-reduction for recreational use as well as guidelines for therapeutic use. Other drugs in covers a bit are 2C-B, MDA, MDE, MMDA, MBDB. Mostly the empathogen class. And yes, Ann and Sasha Shulgin contribute to the book. It'd be nice to see an updated edition.