File Archive - Benzodiazepines Documents - Effects of benzodiazepines on explicit memory in a paediatric surgery setting (2003)

News Groups Blog Forum Chat Video Audio Images Documents Wiki Home

		Drugs Forum > File Archive > Documents > CHEMICAL & (SEMI-) SYNTHETIC DRUGS > Downers Documents > Benzodiazepines Documents
Effects of benzodiazepines on explicit memory in a paediatric surgery setting (2003)

Tags

FAQ n Rules

Mark Forums Read

Notices

Create a FREE account now to get access to more forums, more videos, more music, more documents, more images, more reviews, more news about drugs and much more functionality.
Start posting now, join our groups or create your unique profile.

links

Benzodiazepines Documents

New entries announced in forum Downers and sleeping pills

Allowances: 4.88 Mbytes/3.20 Mbytes used

[RSS Feed]

Entries

Effects of benzodiazepines on explicit memory in a paediatric surgery setting (2003)

Left click: open entry/Right click: save entry

Psychopharmacology (2003) 168:377–386

Susan E. Buffett-Jerrott · Sherry H. Stewart ·

G. Allen Finley · Heather Lee Loughlan

Abstract Rationale: Many laboratory-based studies indicatethat benzodiazepines impair explicit memory performance, increase sedation, and impair attention.

Objectives: The present study was designed to extend prior lab-based findings to an applied setting in which the amnestic effects of benzodiazepines may be beneficial for users. In addition, the study extended the previous adult focused research by examining the cognitive effects of benzodiazepines in children.
Methods: The present study examined the use of a specific benzodiazepine (midazolam) as a premedicant among 40 children aged 4–6 years old having ear tube (myringotomy) surgery, who were randomly assigned to receive midazolam or placebo.
Results: Consistent with previous studies, the results indicated that midazolam causes significant amnesia on a cued recall task. In addition, free recall for post-drug events were also impaired by midazolam relative to placebo, indicating that benzodiazepine-induced amnesia occurs even for highly salient information.
Conclusions: Overall, it appears that benzodiazepines do impair memory in a pediatric population. This amnesia was not secondary to the inattention and sedation also caused by midazolam administration. The theoretical and clinical implications of these findings are discussed, as are potential future studies.

Discussion Thread

Category Benzodiazepines Documents

Submitted by Jatelka

02-03-2008
284.98 Kbytes Hits 3
Keywords: memory midazolam amnesia

Category

Forum Jump

Sitelinks:	Site Functions:
Homepage Wiki Documents Image Gallery Audio Video Forum Blog Groups News	Site Rules Frequently Asked Questions Register to Participate Did you forget your password? All Threads

All times are GMT +1. The time now is 13:45.