File Archive - CHEMICAL & (SEMI-) SYNTHETIC DRUGS - Arrhythmogenic mechanisms of non-sedating antihistamines

News Groups Blog Forum Chat Video Audio Images Documents Wiki Home

		Drugs Forum > File Archive > Documents > CHEMICAL & (SEMI-) SYNTHETIC DRUGS
Arrhythmogenic mechanisms of non-sedating antihistamines

Tags

FAQ n Rules

Mark Forums Read

Notices

Create a FREE account now to get access to more forums, more videos, more music, more documents, more images, more reviews, more news about drugs and much more functionality.
Start posting now, join our groups or create your unique profile.

links

CHEMICAL & (SEMI-) SYNTHETIC DRUGS

Note that this section is not about chemistry.

Allowances: 4.88 Mbytes/4.69 Mbytes used

[RSS Feed]

Entries

Arrhythmogenic mechanisms of non-sedating antihistamines

Left click: open entry/Right click: save entry

Mechanistic studies showed that blockade of IKr channels by non-sedating anti-histamines leads to prolongation of the monophasic action potential (QT interval on surface electrocardiogram) which may then induce the development of early after-depolarization and dispersion of repolarisation leading to torsades de pointes through re-entry mechanism.

Discussion Thread

Category CHEMICAL & (SEMI-) SYNTHETIC DRUGS

Submitted by Bajeda

20-06-2007
168.07 Kbytes Hits 64

Category

Forum Jump

Sitelinks:	Site Functions:
Homepage Wiki Documents Image Gallery Audio Video Forum Blog Groups News	Site Rules Frequently Asked Questions Register to Participate Did you forget your password? All Threads

All times are GMT +1. The time now is 15:06.