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Ecstasy (MDMA, MDEA, MDA) Documents
Documents about MDMA, MDEA, MDA, XTC, E
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  "Partying" hard: party style, motives for and effects of MDMA use at rave parties (2005) Left click: open entry/Right click: save entry
Substance use and Misuse 2005;40(9-10):1479-502

M ter Bogt TF, Engels RC.

This study examines motives for and consequences of MDMA use at different types of dance parties in the Netherlands (2001 and 2002). Participants were 490 visitors of three different types of rave parties,...

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Submitted by Jatelka Find all entries from this user
30-05-2008
138.73 Kbytes Hits 132
Keywords: mdma mdma-use
  "The Great Unmentionable": Exploring the Pleasures and Benefits of Ecstasy from the Perspectives of Drug Users (2008) Left click: open entry/Right click: save entry
Drugs (Abingdon, England) 2008;15(4):329-349

Hunt G, Evans K

Explores the elements of pleasure in the drug-using experiences of young ecstacy users in the San Fransisco Bay area

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Submitted by Jatelka Find all entries from this user
15-01-2009
307.28 Kbytes Hits 87
Keywords: mdma-use
  3,4-Dihydroxymethamphetamine (HHMA). A Major In Vivo MDMA Metabolite in Humans (2001) Left click: open entry/Right click: save entry
Chemical Research in Toxicology 2001 Sep;14(9):1203-8

Segura M, Ortuño J, Farré M, McLure JA, Pujadas M, Pizarro N, Llebaria A, Joglar J, Roset PN, Segura J, de La Torre R.

There is evidence that some heavy users of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) show signs of...
 
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Submitted by Jatelka Find all entries from this user
30-01-2007
70.61 Kbytes Hits 141
Keywords: mdma
  3,4-Methylenedioxy analogues of amphetamine: defining the risks to humans (1999) Left click: open entry/Right click: save entry
Neuroscience and Biobehavioural Reviews 1999 Mar;23(4):539-53

Hegadoren KM, Baker GB, Bourin M.

The 3,4-methylenedioxy analogues of amphetamine [MDMA ("Ecstasy", "Adam"), MDA ("Love") and MDE ("Eve")] are recreational drugs that produce feelings of euphoria and energy and a desire to...
 
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Submitted by Jatelka Find all entries from this user
02-09-2009
123.74 Kbytes Hits 15
Keywords: mda mde mdma
  3,4-Methylenedioxymethamphetamine (ecstasy) activates skeletal muscle nicotinic acetylcholine receptors (2005) Left click: open entry/Right click: save entry
Journal of Pharmacology and Experimental Therapeutics 2005 Sep;314(3):1267-73

Klingler W, Heffron JJ, Jurkat-Rott K, O'sullivan G, Alt A, Schlesinger F, Bufler J, Lehmann-Horn F

Adverse 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) effects are usually ascribed to neurotransmitter...
 
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Submitted by Jatelka Find all entries from this user
11-08-2008
320.15 Kbytes Hits 32
  3,4-Methylenedioxymethamphetamine (ecstasy) and alcohol interactions in humans: psychomotor performance, subjective effects, and pharmacokinetics (2002) Left click: open entry/Right click: save entry
Journal of Pharmacology and Experimental Therapeutics 2002 Jan;300(1):236-44

Hernández-López C, Farré M, Roset PN, Menoyo E, Pizarro N, Ortuño J, Torrens M, Camí J, de La Torre R

3,4-Methylenedioxymethamphetamine (MDMA) is frequently consumed in association with alcohol. The effect of this...
 
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Submitted by Alfa Find all entries from this user
13-06-2006
153.90 Kbytes Hits 51
Keywords: psychomotor interactions pharmacokinetics mdma alcohol
  3,4-methylenedioxymethamphetamine (ecstasy) inhibits dyskinesia expression and normalizes motor activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates (2003) Left click: open entry/Right click: save entry
Journal of Neuroscience 2003 Oct 8;23(27):9107-15

Iravani MM, Jackson MJ, Kuoppamäki M, Smith LA, Jenner P.

Ecstasy [3,4-methylenedioxymethamphetamine (MDMA)] was shown to prolong the action of L-3,4-dihydroxyphenylalanine (L-DOPA) while suppressing dyskinesia in a single patient with...
 
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Submitted by Jatelka Find all entries from this user
02-09-2009
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Keywords: dyskinesia l-dopa mdma parkinsonism
  3,4-Methylenedioxymethamphetamine (MDMA) abuse may cause oxidative stress and potential free radical damage (2003) Left click: open entry/Right click: save entry
Published in Free Radical Research 2003 May;37(5):491-7.

Authors: Jun F. Zhou; Peng Chen; Ye H. Zhou; Liang Zhang; Huai H. Chen

OBJECTIVE: To investigate whether 3,4-methylenedioxymethamphetamine abuse (MDMA abuse) may cause oxidative stress and potential free radical damage in the bodies...
 
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Submitted by ThirdEyeFloond Find all entries from this user
13-01-2008
96.97 Kbytes Hits 58
Keywords: mdma neurotoxicity
  3,4-Methylenedioxymethamphetamine (MDMA) Administration to Rats Does Not Decrease Levels of the Serotonin Transporter Protein or Alter its Distribution Between Endosomes and the Plasma Membrane (2005) Left click: open entry/Right click: save entry
JPET Fast Forward. Published on June 7, 2005

Xiaoying Wang, Michael H. Baumann, Heng Xu, Marisela Morales and Richard B. Rothman
 
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Submitted by Alfa Find all entries from this user
04-06-2006
315.79 Kbytes Hits 41
Keywords: serotonin mdma
  3,4-Methylenedioxymethamphetamine (MDMA) as a unique model of serotonin receptor function and serotonin-dopamine interactions (2001) Left click: open entry/Right click: save entry
Journal of Pharmacology and Experimental Therepeutics Jun;297(3):846-52

Bankson MG, Cunningham KA

(+)-3,4-Methylenedioxymethamphetamine (MDMA; "ecstasy"; "X"; "E") is a popular recreational amphetamine analog that produces a unique set of effects in humans and animals. MDMA use is often...
 
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Submitted by Jatelka Find all entries from this user
08-08-2006
189.19 Kbytes Hits 35
Keywords: dopamine mdma serotonin
  3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings (2007) Left click: open entry/Right click: save entry
Psychopharmacology (Berl) 2007,189(4):407-424

Baumann MH, Wang X, Rothman RB

RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA) is a widely abused illicit drug. In animals, high-dose administration of MDMA produces deficits in serotonin (5-HT) neurons (e.g., depletion of forebrain 5-HT)...
 
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Submitted by Jatelka Find all entries from this user
13-05-2008
359.74 Kbytes Hits 39
Keywords: mdma neurotoxicity
  3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) and driving impairment (2001) Left click: open entry/Right click: save entry
Journal of Forensic Sciences 2001 Nov;46(6):1426-33

Logan BK, Couper FJ

3,4-Methylenedioxymethamphetamine, or MDMA, is increasing in popularity in the United States as a drug of abuse. It has stimulant and empathogenic mood altering properties with the potential to affect psychomotor skills...
 
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Submitted by Jatelka Find all entries from this user
30-04-2007
2.66 Mbytes Hits 12
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  3,4-Methylenedioxymethamphetamine induces monoamine release, but not toxicity, when administered centrally at a concentration occurring following a peripherally injected neurotoxic dose (2001) Left click: open entry/Right click: save entry
Psychopharmacology 2001 Mar;154(3):251-60

Esteban B, O'Shea E, Camarero J, Sanchez V, Green AR, Colado MI

These data demonstrate that MDMA when injected directly into the brain produces 5-HT release but no neurotoxicity, suggesting that it must be metabolised peripherally in order to...
 
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Submitted by Bajeda Find all entries from this user
01-10-2007
124.21 Kbytes Hits 35
Keywords: 5-hydroxytryptamine neurotoxicity mdma
  5-HTTLPR polymorphism, mood disorders and MDMA use in a 3-year follow-up study. (2010) Left click: open entry/Right click: save entry
Martın-Santos, R., Torrens, M., Poudevida, S., Langohr, K., Cuyás, E., Pacifici, R., et al.
Addiction biology, 15(1), 15–22. (2010)

Abstract
A 3-year longitudinal prospective study was conducted to compare the incidence of substance use disorders (SUD) and non-substance use disorders (NSUD)...

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Submitted by staples Find all entries from this user
01-01-2010
143.32 Kbytes Hits 4
Keywords: cannabis ecstasy mdma
  A behavioural economic analysis of alcohol, amphetamine, cocaine and ecstasy purchases by polysubstance misusers. (2004) Left click: open entry/Right click: save entry
Drug Alcohol Depend. 2004 Oct 5;76(1):93-9

Harry R. Sumnall, Elizabeth Tyler, Graham F. Wagstaff, Jon C. Cole

Behavioural economic models of substance choice describe the relationship between changes in unit price and consumption. As the majority of UK non-dependent substance misusers are...

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Submitted by ThirdEyeFloond Find all entries from this user
16-01-2008
103.98 Kbytes Hits 303
Keywords: alcohol amphetamine mdma poly-drug polysubstance
  A Bitter Pill: Overview of Ecstasy (MDMA, MDA) Related Fatalities (2004) Left click: open entry/Right click: save entry
Psychopharmacology 2004 May;173(3-4):242-8

Schifano F

RATIONALE: The issue of ecstasy-related fatalities has extensively attracted the attention of both the media and the general public, but less so of the scientific literature. OBJECTIVES: The aim of the present review is to focus on the...
 
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Submitted by Jatelka Find all entries from this user
30-04-2007
151.35 Kbytes Hits 120
Keywords: mda mdma
  A clash of policy approaches: The rise (and fall?) of Dutch harm reduction policies towards ecstasy consumption (2005) Left click: open entry/Right click: save entry
International Journal of Drug Policy 16 (2005) 65-72

Uitermark and Cohen

This paper describes the origins and evolution of Dutch harm reduction policies towards ecstasy. It is argued that the national government has allowed and supported local stakeholders to experiment with harm reduction...

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Submitted by Bajeda Find all entries from this user
10-04-2007
201.75 Kbytes Hits 79
Keywords: mdma policy ecstasy harm-reduction
  A Clinical Plan For MDMA in the Treatment of Post Traumatic Stress Disorder: Partnering with The FDA (Doblin, 2002) Left click: open entry/Right click: save entry
Originally published in The Journal of Psychoactive Drugs.

"The article presents the rationale behind MAPS (Multi-Disciplinary Association for Psychedelic Studies) efforts to sponsor research... investigating MDMA's effects in PTSD"
 
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Submitted by Jatelka Find all entries from this user
07-02-2007
132.86 Kbytes Hits 66
Keywords: ptsd treatment mdma
  A Comparative Study on the Acute and Long Term Effects of MDMA and 3,4-dihydroxymethamphetamine (HHMA) on Brain Monoamine Levels After IP or Striatal Administration in Mice (2005) Left click: open entry/Right click: save entry
British Journal of Pharmacology (2005) 144 231-241

Escobedo et al
 
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Submitted by Jatelka Find all entries from this user
01-02-2007
237.51 Kbytes Hits 60
Keywords: monoamine mdma
  A Comparison of the Physiological, Behavioural, Neurochemical and Microglial Effects of Methamphetamine and MDMA in the Mouse (2008) Left click: open entry/Right click: save entry
Neuroscience 2008 Jan 24;151(2):533-43

Fantegrossi WE, Ciullo JR, Wakabayashi KT, De La Garza R 2nd, Traynor JR, Woods JH.

3,4-Methylenedioxymethamphetamine (MDMA) and methamphetamine (METH) are amphetamine analogues with similar persistent neurochemical effects in the mouse which some have...

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Submitted by Jatelka Find all entries from this user
09-01-2008
873.22 Kbytes Hits 64
Keywords: pharmacology neurotoxicity methamphetamine mdma
  A Long-Term Ecstasy Related Change in Visual Perception (2007) Left click: open entry/Right click: save entry
Psychopharmacology 2007 Aug;193(3):437-46

Brown J, Edwards M, McKone E, Ward J.

RATIONALE: The present study provides the first evidence of the long-term consequences of ecstasy use on visual processes thought to reflect serotonergic functions in the occipital lobe....
 
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03-01-2008
223.80 Kbytes Hits 54
Keywords: mdma visual
  A method of conducting thereputic sessions with MDMA (1998) Left click: open entry/Right click: save entry
Journal of Psychoactive Drugs 1998 30(4)

Greer and Tolbert

A method for preparing clients and conducting therapeutic sessions with 3,4-methylenedioxymethamphetamine (MDMA) is described, with emphasis on the need for careful attention to the mental set of therapists and clients and the...
 
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Submitted by Heretic.Ape. Find all entries from this user
19-07-2007
829.37 Kbytes Hits 31
Keywords: therapy mdma
  A Prospective Cohort Study on Sustained Effects of Low-Dose Ecstasy Use on the Brain in New Ecstasy Users (2007) Left click: open entry/Right click: save entry
Neuropsychopharmacology 2007 Feb;32(2):458-70

de Win MM, Reneman L, Jager G, Vlieger EJ, Olabarriaga SD, Lavini C, Bisschops I, Majoie CB, Booij J, den Heeten GJ, van den Brink W

It is debated whether ecstasy use has neurotoxic effects on the human brain and what the effects are of a low...
 
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21-11-2006
232.96 Kbytes Hits 71
Keywords: mdma
  A Review of The Acute Effects of MDMA in Healthy Volunteers (2006) Left click: open entry/Right click: save entry
Journal of Psychopharmacology 2006 Mar;20(2):176-87

Dumont GJ, Verkes RJ.

This review of the literature aims to identify the acute effects of MDMA (ecstasy) in healthy volunteers. The wide range of relevant but methodologically diverse tests was .rst grouped into clusters to allow an...
 
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02-08-2006
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  A role for oxytocin and 5-HT1A receptors in the prosocial effects of 3,4 methylenedioxymethamphetamine (2007) Left click: open entry/Right click: save entry
Neuroscience 2007 May 11;146(2):509-14

Thompson MR, Callaghan PD, Hunt GE, Cornish JL, McGregor IS

The drug 3,4 methylenedioxymethamphetamine (MDMA; ecstasy) has a widely documented ability to increase feelings of love and closeness toward others. The present study investigated whether...
 
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Submitted by Bajeda Find all entries from this user
28-04-2007
901.52 Kbytes Hits 44
Keywords: mdma
  A structured review of reasons for ecstasy use and related behaviours: pointers for future research (2009) Left click: open entry/Right click: save entry
BMC Public Health 2009 Jul 13;9:230

Peters GJ, Kok G.

BACKGROUND: While the health risks of using ecstasy warrant intervention development, a recent meta-analysis of determinants of ecstasy use identified a number of lacunae in the literature. Specifically, no studies were included that...

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Submitted by Jatelka Find all entries from this user
20-08-2009
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  Action of MDMA and it's Metabolites on Arginine Vasopressin Release (2002) Left click: open entry/Right click: save entry
Annals of the New York Academy of Science 2002 Jun;965:399-409

Fallon JK, Shah D, Kicman AT, Hutt AJ, Henry JA, Cowan DA, Forsling M.

3,4-Methylenedioxymethamphetamine (MDMA) has been reported to cause hyponatraemia, which appears to result from inappropriate secretion of the antidiuretic...
 
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01-05-2007
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  Actions of 3,4-methylenedioxymethamphetamine (MDMA) on cerebral dopaminergic, serotonergic and cholinergic neurons (2008) Left click: open entry/Right click: save entry
Pharmacology Chemistry and Behaviour 2008 Aug;90(2):198-207

Gudelsky GA, Yamamoto BK

3,4-Methylenedioxymethamphetamine (MDMA) is an amphetamine derivative and a popular drug of abuse that exhibits mild hallucinogenic and rewarding properties and engenders feelings of connectedness and...
 
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Submitted by Metomni Find all entries from this user
11-08-2008
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Keywords: dopamine mdma methamphetamine serotonin
  Activation of protein kinase C (PKC) by 3,4-methylenedioxymethamphetamine (MDMA) occurs through the stimulation of serotonin receptors and transporter (1997) Left click: open entry/Right click: save entry
Neuropsychopharmacology. 1997 Sep;17(3):117-29

Kramer HK, Poblete JC, Azmitia EC.

This report further characterizes the intermediate metabolic effects of the psychotropic amphetamine derivative, 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy"), on the activity of second...
 
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26-06-2006
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  Acute dose of MDMA (75 mg) impairs spatial memory for location but leaves contextual processing of visuospatial information unaffected (2006) Left click: open entry/Right click: save entry
Psychopharmacology 2006 Mar 1,Published on-line

Kuypers KP, Ramaekers JG

RATIONALE: Research concerning spatial memory in 3,4-methylenedioxymethamphetamine (MDMA) users has presented conflicting results showing either the presence or absence of spatial memory deficits. Two factors may have...
 
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Submitted by Jatelka Find all entries from this user
21-05-2008
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Keywords: memory cognition mdma
  Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on behavioral measures of impulsivity: alone and in combination with alcohol (2006) Left click: open entry/Right click: save entry
Neuropsychopharmacology 2006 May;31(5):1048-55

Ramaekers JG, Kuypers KP.

The use of 3,4-methylenedioxymethamphetamine (MDMA) has frequently been associated with increased levels of impulsivity during abstinence. The effects of MDMA on measures of impulsivity, however, have not yet been...
 
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Submitted by Jatelka Find all entries from this user
24-11-2006
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Keywords: alcohol mdma ethanol
  Acute effects of 3,4-methylenedioxymethamphetamine alone and in combination with ethanol on the immune system in humans (2001) Left click: open entry/Right click: save entry
Journal of Pharmacology and Experimental Therapeutics 2001 Jan;296(1):207-15

Pacifici R, Zuccaro P, Hernandez López C, Pichini S, Di Carlo S, Farré M, Roset PN, Ortuño J, Segura J, Torre RL.

Cell-mediated immune response and release of cytokines after the administration of...
 
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30-04-2007
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Keywords: mdma alcohol ethanol
  Acute MDMA and ethanol interaction effects on psychomotor performance Left click: open entry/Right click: save entry
J. K. Buitelaar,1 J. M. A. van Gerven2 & R. J. Verkes1, 1Unit for Clinical Psychopharmacology and Neuropsychiatry(UCPN), Dept. Psychiatry, , University Medical Centre Nijmegen, The Netherlands 2Centre for Human Drug Research, Leiden, The Netherlands

Introduction: A considerable percentage of...
 
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13-04-2009
127.34 Kbytes Hits 8
  Acute neuropsychological effects of MDMA and ethanol (co-)administration in healthy volunteers (2008) Left click: open entry/Right click: save entry
Psychopharmacology (Berl) e-published February 28 2008

Dumont GJ, Wezenberg E, Valkenberg MM, de Jong CA, Buitelaar JK, van Gerven JM, Verkes RJ

RATIONALE: In Western societies, a considerable percentage of young people expose themselves to 3,4-methylenedioxymethamphetamine (MDMA or...
 
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Submitted by Jatelka Find all entries from this user
20-03-2008
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Keywords: alcohol ecstasy mdma
  Acute pharmacological and neurophysiological effects of MDMA in humans (2002) Left click: open entry/Right click: save entry
Journal of Psychoactive Drugs Volume 34 (2) April-June 2002

Franz Vollenweider et al
 
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Submitted by Alfa Find all entries from this user
04-06-2006
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  Acute Psychological Effects of MDMA are Attenuated by the SSRI Citalopram (2000) Left click: open entry/Right click: save entry 4 *
Neuropsychopharmacology 22;513-521 2000

Liechti et al

3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy") is a recreational drug that has been shown to release serotonin (5-HT) and dopamine (DA) in animals. The effect of MDMA on 5-HT release can be blocked by 5-HT uptake inhibitors such as...
 
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12-08-2006
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  Acute psychomotor effects of MDMA and ethanol (co-) administration over time in healthy volunteers Left click: open entry/Right click: save entry
AbstractIn Western societies, a considerable percentage of young people use 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy'). The use of alcohol (ethanol) in combination with ecstasy is common. The aim of the present study was to assess the acute psychomotor and subjective effects of (co-)...  
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Submitted by Gradient Find all entries from this user
23-04-2009
312.40 Kbytes Hits 11
  Acute Toxic Effects of Club-Drugs (2004) Left click: open entry/Right click: save entry
Journal of Psychoactive Drugs 2004 Sep;36(3):303-13

Gable RS

This article summarizes the short-term physiological toxicity and the adverse behavioral effects of four substances (GHB, ketamine, MDMA, and Rohypnol) that have been used at latenight dance clubs. The two primary data sources...

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12-11-2007
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  ADAM or Evil? Left click: open entry/Right click: save entry

  MDMA history comic strip.  
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Submitted by enquirewithin Find all entries from this user
13-01-2008
2.85 Mbytes Hits 30
  Age-dependent differences in sensitivity and sensitization to cannabinoids and 'club drugs' in male adolescent and adult rats (2008) Left click: open entry/Right click: save entry
Addiction Biology 2008 Sep;13(3-4):277-86

Wiley JL, Evans RL, Grainger DB, Nicholson KL.

Lifelong substance abuse is often initiated during adolescence; yet, most pre-clinical research in this area has been conducted in adult animals. Substantial evidence exists that the brain development...

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24-02-2009
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